TY  - JOUR
A1  - Maukel, Lisa-Marie
A1  - Schmeller, Sandra
A1  - Weidner, Gerdi
A1  - Beyersmann, Jan
A1  - Spaderna, Heike
T1  - Psychosocial Risk and Recurrent Hospitalizations
T2  - Journal of cardiovascular development and disease
N2  - Background: Women experience higher rates of adverse events and first rehospitalization after left ventricular assist device (LVAD) implantation compared with men. This study investigated the role of sex and preimplant psychosocial risk in recurrent hospitalizations. Methods: Data from 20,123 INTERMACS patients (21.3% women) were analyzed. Cumulative transition rates (e.g., home to hospitalization) were estimated and Andersen–Gill models, adjusted for covariates, examined the association between sex, preimplant psychosocial risk, and cumulative transition hazards for rehospitalization. State occupation probabilities, the mean number of hospitalizations, and the cumulative average length of hospital stay were calculated and stratified by sex and psychosocial risk. Results: Psychosocial risk preimplant was more prevalent in men than in women (21.4% vs. 17.5%, p < 0.001). The interaction of female sex and psychosocial risk increased rehospitalization hazards, independently of covariates [HRadj 1.11, 95% CI (1.01–1.22), p = 0.036]. One-year postimplant, women with vs. without psychosocial risk had 2.2 vs. 1.8 hospitalizations, while men experienced 1.8 vs. 1.7 hospitalizations, respectively. Women with vs. without psychosocial risk spent 20 vs.16 days hospitalized, and men 15 vs. 14 days (all p < 0.001). Conclusions: Preimplant psychosocial risk independently contributed to recurrent hospitalizations post-LVAD, particularly affecting women. The early identification and management of these factors may reduce rehospitalizations and improve clinical outcomes.
KW  - heart failure
KW  - clinical outcomes
KW  - rehospitalization
KW  - women
KW  - LVAD
KW  - psychosocial risk
Y1  - 2025
UR  - https://ubt.opus.hbz-nrw.de/frontdoor/index/index/docId/2925
UR  - https://nbn-resolving.org/urn:nbn:de:hbz:385-1-29251
VL  - 2025
IS  - 12 / 6
PB  - MDPI
CY  - Basel
ER  -