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Psychosocial Risk and Health Behaviors as Predictors of Clinical Events in Patients Wait-Listed for a New Heart: Results from 7 Years of Follow-Up

  • We examined the long-term relationship of psychosocial risk and health behaviors on clinical events in patients awaiting heart transplantation (HTx). Psychosocial characteristics (e.g., depression), health behaviors (e.g., dietary habits, smoking), medical factors (e.g., creatinine), and demographics (e.g., age, sex) were collected at the time of listing in 318 patients (82% male, mean age = 53 years) enrolled in the Waiting for a New Heart Study. Clinical events were death/delisting due to deterioration, high-urgency status transplantation (HU-HTx), elective transplantation, and delisting due to clinical improvement. Within 7 years of follow-up, 92 patients died or were delisted due to deterioration, 121 received HU-HTx, 43 received elective transplantation, and 39 were delisted due to improvement. Adjusting for demographic and medical characteristics, the results indicated that frequent consumption of healthy foods (i.e., foods high in unsaturated fats) and being physically active increased the likelihood of delisting due improvement, while smoking and depressive symptoms were related to death/delisting due to clinical deterioration while awaiting HTx. In conclusion, psychosocial and behavioral characteristics are clearly associated with clinical outcomes in this population. Interventions that target psychosocial risk, smoking, dietary habits, and physical activity may be beneficial for patients with advanced heart failure waiting for a cardiac transplant.

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Metadaten
Author:Kathleen Gali, Gerdi Weidner, Jacqueline Mathilde Albertine Smits, Jan Beyersmann, Heike Spaderna-Klein
URN:urn:nbn:de:hbz:385-1-18717
DOI:https://doi.org/10.3390/life11121438
Parent Title (English):Life
Publisher:MDPI
Place of publication:Basel
Document Type:Article
Language:English
Date of completion:2021/12/20
Date of publication:2021/12/20
Publishing institution:Universität Trier
Contributing corporation:The publication was funded by the Open Access Fund of Universität Trier and the German Research Foundation (DFG)
Release Date:2022/05/17
Tag:advanced heart failure; depression; heart transplant; physical activity; smoking
GND Keyword:Auswirkung; Gesundheitsverhalten; Herztransplantation; Längsschnittuntersuchung; Psychosoziale Situation; Wartezeit
Volume (for the year ...):2021
Issue / no.:Band 11, Heft 12 (2021)
Number of pages:14
Institutes:Fachbereich 1 / Pflegewissenschaft
Licence (German):License LogoCC BY: Creative-Commons-Lizenz 4.0 International

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