This dissertation focusses on research into the personality construct of action vs. state orientation. Derived from the Personality-Systems-Interaction Theory (PSI Theory), state orientation is defined as a low ability to self-regulate emotions and associated with many adverse consequences – especially under stress. Because of the high prevalence of state orientation, it is a very important topic to investigate factors that help state-oriented people to buffer these adverse consequences. Action orientation, in contrast, is defined as a high ability to self-regulate own emotions in a very specific way: through accessing the self. The present dissertation demonstrates this theme in five studies, using a total of N = 1251 participants with a wide age range, encompassing different populations (students, non-student population (people from the coaching and therapy sector), applying different operationalisations to investigate self-access as a mediator or an outcome variable. Furthermore, it is tested whether the popular technique of mindfulness - that is advertised as a potent remedy for bringing people closer to the self -really works for everybody. The findings show that the presumed remedy is rather harmful for state-oriented individuals. Finally, an attempt to ameliorate these alienating effects, the present dissertation attempts to find theory-driven, and easy-to-apply solution how mindfulness exercises can be adapted.

Knowledge acquisition comprises various processes. Each of those has its dedicated research domain. Two examples are the relations between knowledge types and the influences of person-related variables. Furthermore, the transfer of knowledge is another crucial domain in educational research. I investigated these three processes through secondary analyses in this dissertation. Secondary analyses comply with the broadness of each field and yield the possibility of more general interpretations. The dissertation includes three meta-analyses: The first meta-analysis reports findings on the predictive relations between conceptual and procedural knowledge in mathematics in a cross-lagged panel model. The second meta-analysis focuses on the mediating effects of motivational constructs on the relationship between prior knowledge and knowledge after learning. The third meta-analysis deals with the effect of instructional methods in transfer interventions on knowledge transfer in school students. These three studies provide insights into the determinants and processes of knowledge acquisition and transfer. Knowledge types are interrelated; motivation mediates the relation between prior and later knowledge, and interventions influence knowledge transfer. The results are discussed by examining six key insights that build upon the three studies. Additionally, practical implications, as well as methodological and content-related ideas for further research, are provided.

The COVID-19 pandemic has affected schooling worldwide. In many places, schools closed for weeks or months, only part of the student body could be educated at any one time, or students were taught online. Previous research discloses the relevance of schooling for the development of cognitive abilities. We therefore compared the intelligence test performance of 424 German secondary school students in Grades 7 to 9 (42% female) tested after the first six months of the COVID-19 pandemic (i.e., 2020 sample) to the results of two highly comparable student samples tested in 2002 (n = 1506) and 2012 (n = 197). The results revealed substantially and significantly lower intelligence test scores in the 2020 sample than in both the 2002 and 2012 samples. We retested the 2020 sample after another full school year of COVID-19-affected schooling in 2021. We found mean-level changes of typical magnitude, with no signs of catching up to previous cohorts or further declines in cognitive performance. Perceived stress during the pandemic did not affect changes in intelligence test results between the two measurements.

Every action we perform, no matter how simple or complex, has a cognitive representation. It is commonly assumed that these are organized hierarchically. Thus, the representation of a complex action consists of multiple simpler actions. The representation of a simple action, in turn, consists of stimulus, response, and effect features. These are integrated into one representation upon the execution of an action and can be retrieved if a feature is repeated. Depending on whether retrieved features match or only partially match the current action episode, this might benefit or impair the execution of a subsequent action. This pattern of costs and benefits results in binding effects that indicate the strength of common representation between features. Binding effects occur also in more complex actions: Multiple simple actions seem to form representations on a higher level through the integration and retrieval of sequentially given responses, resulting in so-called response-response binding effects. This dissertation aimed to investigate what factors determine whether simple actions form more complex representations. The first line of research (Articles 1-3) focused on dissecting the internal structure of simple actions. Specifically, I investigated whether the spatial relation of stimuli, responses, or effects, that are part of two different simple actions, influenced whether these simple actions are represented as one more complex action. The second line of research (Articles 2, 4, and 5) investigated the role of context on the formation and strength of more complex action representations. Results suggest that spatial separation of responses as well as context might affect the strength of more complex action representations. In sum, findings help to specify assumptions on the structure of complex action representations. However, it may be important to distinguish factors that influence the strength and structure of action representations from factors that terminate action representations.

Der Beitrag diskutiert das Verhältnis von allgemeiner und beruflicher Bildung mithilfe einer pädagogischen Theorie der Organisation. Allgemeine Erwachsenen- und berufliche Bildung treffen sich darin, Prozess und Ergebnis der wechselseitigen Auseinandersetzung zwischen Organisationen und Individuen zu sein. Organisationen sind nicht nur Kontext von Bildung, sie sind selber gebildet und wirken pädagogisch. Der Beitrag erschließt die Funktion und Eigenlogik der Organisation in ihrem Verhältnis zu den Grundbegriffen der Erziehungswissenschaft. Der Vorschlag ermöglicht es, Lernen, Sozialisation, Erziehung, Bildung und Kompetenz in ihrer Geltung für die ineinander verflochtene Strukturdynamik von Organisation und Subjekt zu differenzieren. Als Alternative zur geläufigen Organisationsvergessenheit der Pädagogik integriert die differenzierende Ordnung dieser Begriffe eine erziehungswissenschaftliche Perspektive auf Individuum und Organisation.

The present dissertation was developed to emphasize the importance of self-regulatory abilities and to derive novel opportunities to empower self-regulation. From the perspective of PSI (Personality Systems Interactions) theory (Kuhl, 2001), interindividual differences in self-regulation (action vs. state orientation) and their underlying mechanisms are examined in detail. Based on these insights, target-oriented interventions are derived, developed, and scientifically evaluated. The present work comprises a total of four studies which, on the one hand, highlight the advantages of a good self-regulation (e.g., enacting difficult intentions under demands; relation with prosocial power motive enactment and well-being). On the other hand, mental contrasting (Oettingen et al., 2001), an established self-regulation method, is examined from a PSI perspective and evaluated as a method to support individuals that struggle with self-regulatory deficits. Further, derived from PSI theory`s assumptions, I developed and evaluated a novel method (affective shifting) that aims to support individuals in overcoming self-regulatory deficits. Thereby affective shifting supports the decisive changes in positive affect for successful intention enactment (Baumann & Scheffer, 2010). The results of the present dissertation show that self-regulated changes between high and low positive affect are crucial for efficient intention enactment and that methods such as mental contrasting and affective shifting can empower self-regulation to support individuals to successfully close the gap between intention and action.

Der vorliegende Text ist als Mantelpapier im Rahmen einer kumulativen Dissertation an der Universität Trier angenommen worden. Er dient der Zusammenfassung, Reflexion und erweiterten theoretischen Betrachtung der empirischen Einzelbeiträge, die alle einen Einzelaspekt des Gesamtgeschehens „Innovationslabor zur Unterstützung unternehmerischen Lernens und der Entwicklung sozialer Dienstleistungsinnovationen“ behandeln. Dabei wird das Innovationslabor grundsätzlich als Personalentwicklungsmaßnahme aufgefasst. In einem gedanklichen Experiment werden die Ergebnisse auf Organisationen der Erwachsenen- und Weiterbildung übertragen. Das Besondere dieses Rahmenpapiers ist die Verbindung eines relationalen Raumverständnisses mit der lerntheoretischen Untermauerung des Gegenstandes „Innovationslabor“ aus der Perspektive der Organisationspädagogik und Erwachsenenbildung. Die Ergebnisse zeigen den Lernraum Labor als abseits des Arbeitslebens, als semi-autonom angebundenen Raum, wo Lernprozesse auf unterschiedlichen Ebenen stattfinden und angestoßen werden. Das Labor wird als heterotoper (Lern-)Raum diskutiert. Neu ist auch der Einbezug einer kritischen Perspektive, die bislang im Diskurs um Innovationslabore fehlte: Das Labor wird als prekärer Lernraum charakterisiert. Somit liegt mit dieser Arbeit nun eine grundlegende Ausarbeitung des Labors als Lernraum vor, die zahlreiche weitere Anschlussmöglichkeiten für Forschung ermöglicht.

The search for health information is becoming increasingly important in everyday life, as well as socially and scientifically relevant Previous studies have mainly focused on the design and communication of information. However, the view of the seeker as well as individual differences in skills and abilities has been a neglected topic so far. A psychological perspective on the process of searching for health information would provide important starting points for promoting the general dissemination of relevant information and thus improving health behaviour and health status. Within the present dissertation, the process of seeking health information was thus divided into sequential stages to identify relevant personality traits and skills. Accordignly, three studies are presented that focus on one stage of the process respectively and empirically test potential crucial traits and skills: Study I investigates possible determinants of an intention for a comprehensive search for health information. Building an intention is considered as the basic step of the search process. Motivational dispositions and self-regulatory skills were related to each other in a structural equation model and empirically tested based on theoretical investigations. Model fit showed an overall good fit and specific direct and indirect effects from approach and avoidance motivation on the intention to seek comprehensively could be found, which supports the theoretical assumptions. The results show that as early as the formation of intention, the psychological perspective reveals influential personality traits and skills. Study II deals with the subsequent step, the selection of information sources. The preference for basic characteristics of information sources (i.e., accessibility, expertise, and interaction) is related to health information literacy as a collective term for relevant skills and intelligence as a personality trait. Furthermore, the study considers the influence of possible over- or underestimation of these characteristics. The results show not only a different predictive contribution of health literacy and intelligence, but also the relevance of subjective and objective measurement. Finally, Study III deals with the selection and evaluation of the health information previously found. The phenomenon of selective exposure is analysed, as this can be considered problematic in the health context. For this purpose, an experimental design was implemented in which a varying health threat was suggested to the participants. Relevant information was presented and the selective choice of this information was assessed. Health literacy was tested as a moderator in a function of the induced threat and perceived vulnerability, triggering defence motives on the degree of bias. Findings show the importance of the consideration of the defence motives, which could cause a bias in the form of selective exposure. Furthermore, health literacy even seems to amplify this effect. Results of the three studies are synthesized, discussed and general conclusions are drawn and implications for further research are determined.

The present work explores how theories of motivation can be used to enhance video game research. Currently, Flow-Theory and Self-Determination Theory are the most common approaches in the field of Human-Computer Interaction. The dissertation provides an in-depth look into Motive Disposition Theory and how to utilize it to explain interindividual differences in motivation. Different players have different preferences and make different choices when playing games, and not every player experiences the same outcomes when playing the same game. I provide a short overview of the current state of the research on motivation to play video games. Next, Motive Disposition Theory is applied in the context of digital games in four different research papers, featuring seven studies, totaling 1197 participants. The constructs of explicit and implicit motives are explained in detail while focusing on the two social motives (i.e., affiliation and power). As dependent variables, behaviour, preferences, choices, and experiences are used in different game environments (i.e., Minecraft, League of Legends, and Pokémon). The four papers are followed by a general discussion about the seven studies and Motive Disposition Theory in general. Finally, a short overview is provided about other theories of motivation and how they could be used to further our understanding of the motivation to play digital games in the future. This thesis proposes that 1) Motive Disposition Theory represents a valuable approach to understand individual motivations within the context of digital games; 2) there is a variety of motivational theories that can and should be utilized by researchers in the field of Human-Computer Interaction to broaden the currently one-sided perspective on human motivation; 3) researchers should aim to align their choice of motivational theory with their research goals by choosing the theory that best describes the phenomenon in question and by carefully adjusting each study design to the theoretical assumptions of that theory.

Social innovation became a widely discussed topic in politics, research funding programs, and business development. Recent European and US economic and science policies have set aside significant funds to generate and foster social innovation. In view of current challenges such as digitization, Work 4.0, inclusion or migrant integration, the question of how organizations can be empowered to develop new and innovative approaches and service models to social challenges is becoming increasingly urgent. This especially applies to organizations in the fields of education and social services. In education, implementing new ideas and concepts is usually discussed as educational reform, which mostly addresses changes in policy agendas with consequences for national and international education systems. The concept of social innovation however has a different starting point: the source of new ideas and services are identified new, emergent needs in society or re-conceptualized. Such need-based perspectives might bring new impulses to the field of education. Therefore, this paper identifies important existing strands of social innovation research, which need to be considered in the emerging academic discourse on social innovation in education. Looking at social innovation through an education research lens reveals the close relation between learning, creativity, and innovation. Individuals, teams, and even organizations learn, engage in creative problem solving to create new and innovative products and services. From an organizational education perspective, the questions arise, how social innovation emerges and even more important, how the process of developing social innovation can be supported. After a brief introduction in the concept of social innovation, the paper discusses therefore the sites, where social innovation emerges, social innovators, approaches to foster social innovation as well as promoting and hindering factors for social innovation.

This intervention study explored the effects of a newly developed intergenerational encounter program on cross-generational age stereotyping (CGAS). Based on a biographical-narrative approach, participants (secondary school students and nursing home residents) were invited to share ideas about existential questions of life (e.g., about one’s core experiences, future plans, and personal values). Therefore, the dyadic Life Story Interview (LSI) had been translated into a group format (the Life Story Encounter Program, LSEP), consisting of 10 90-min sessions. Analyses verified that LSEP participants of both generations showed more favorable CGAS immediately after, but also 3 months after the program end. Such change in CGAS was absent in a control group (no LSEP participation). The LSEP-driven short- and long-term effects on CGAS could be partially explained by two program benefits, the feeling of comfort with and the experience of learning from the other generation.

In der Vorrede zur ersten Auflage von Die Welt als Wille und Vorstellung legt Arthur Schopenhauer dem Leser seines Werkes seine Absicht nahe, welche in der Mitteilung eines „einzigen Gedankens“ besteht. Doch dieser mitzuteilende Gedanke wird an keiner Stelle des Werkes explizit und direkt als solchen von Schopenhauer ausgesprochen und genannt. Dies gibt bis heute in der Schopenhauer-Forschung Anlass zu kontroversen Auseinandersetzungen: Wie lautet Schopenhauers „einziger Gedanke“? Wo befindet er sich konkret? Und ist er überhaupt mitteilbar? Trotz zahlreicher Forschungsarbeiten zur Thematik des „einzigen Gedankens“ wurde bisher der Einfluss der indischen Philosophie, genauer des Oupnek’hat, vernachlässigt, obwohl genauestens nachgewiesen und nachgezeichnet werden kann, mit welchen Quellen sich Schopenhauer zum Zeitpunkt der Entstehung seiner Philosophie intensiv beschäftigt hat. Auch verweist er selbst immer wieder auf bestimmte Stellen aus dem Oupnek’hat und zitiert Passagen an ganz wesentlichen Stellen in seinem Werk. Um den „einzigen Gedanken“ im Werk Schopenhauers erfassen zu können, reicht es nicht aus, nur vom Hauptwerk selbst auszugehen, sondern es müssen ebenfalls die Jahre und Schriften während der Entstehung seiner Philosophie bis zum Hauptwerk berücksichtigt werden, und damit verbunden auch die Quellen, die Schopenhauer beeinflusst haben, wozu insbesondere das Oupnek’hat samt seinen eigenen Randnotizen gehört.

Evidence points to autonomy as having a place next to affiliation, achievement, and power as one of the basic implicit motives; however, there is still some research that needs to be conducted to support this notion. The research in this dissertation aimed to address this issue. I have specifically focused on two issues that help solidify the foundation of work that has already been conducted on the implicit autonomy motive, and will also be a foundation for future studies. The first issue is measurement. Implicit motives should be measured using causally valid instruments (McClelland, 1980). The second issue addresses the function of motives. Implicit motives orient, select, and energize behavior (McClelland, 1980). If autonomy is an implicit motive, then we need a valid instrument to measure it and we also need to show that it orients, selects, and energizes behavior. In the following dissertation, I address these two issues in a series of ten studies. Firstly, I present studies that examine the causal validity of the Operant Motive Test (OMT; Kuhl, 2013) for the implicit affiliation and power motives using established methods. Secondly, I developed and empirically tested pictures to specifically assess the implicit autonomy motive and examined their causal validity. Thereafter, I present two studies that investigated the orienting and energizing effects of the implicit autonomy motive. The results of the studies solidified the foundation of the OMT and how it measures nAutonomy. Furthermore, this dissertation demonstrates that nAutonomy fulfills the criteria for two of the main functions of implicit motives. Taken together, the findings of this dissertation provide further support for autonomy as an implicit motive and a foundation for intriguing future studies.

In order to investigate the psychobiological consequences of acute stress under laboratory conditions, a wide range of methods for socially evaluative stress induction have been developed. The present dissertation is concerned with evaluating a virtual reality (VR)-based adaptation of one of the most widely used of those methods, the Trier Social Stress Test (TSST). In the three empirical studies collected in this dissertation, we aimed to examine the efficacy and possible areas of application of the adaptation of this well-established psychosocial stressor in a virtual environment. We found that the TSST-VR reliably incites the activation of the major stress effector systems in the human body, albeit in a slightly less pronounced way than the original paradigm. Moreover, the experience of presence is discussed as one potential factor of influence in the origin of the psychophysiological stress response. Lastly, we present a use scenario for the TSST-VR in which we employed the method to investigate the effects of acute stress on emotion recognition performance. We conclude that, due to its advantages concerning versatility, standardization and economic administration, the paradigm harbors enormous potential not only for psychobiological research, but other applications such as clinical practice as well. Future studies should further explore the underlying effect mechanisms of stress in the virtual realm and the implementation of VR-based paradigms in different fields of application.

Internet interventions have gained popularity and the idea is to use them to increase the availability of psychological treatment. Research suggests that internet interventions are effective for a number of psychological disorders with effect sizes comparable to those found in face-to-face treatment. However, when provided as an add-on to treatment as usual, internet interventions do not seem to provide additional benefit. Furthermore, adherence and dropout rates vary greatly between studies, limiting the generalizability of the findings. This underlines the need to further investigate differences between internet interventions, participating patients, and their usage of interventions. A stronger focus on the processes of change seems necessary to better understand the varying findings regarding outcome, adherence and dropout in internet interventions. Thus, the aim of this dissertation was to investigate change processes in internet interventions and the factors that impact treatment response. This could help to identify important variables that should be considered in research on internet interventions as well as in clinical settings that make use of internet interventions. Study I (Chapter 5) investigated early change patterns in participants of an internet intervention targeting depression. Data from 409 participants were analyzed using Growth Mixture Modeling. Specifically a piecewise model was applied to model change from screening to registration (pretreatment) and early change (registration to week four of treatment). Three early change patterns were identified; two were characterized by improvement and one by deterioration. The patterns were predictive of treatment outcome. The results therefore indicated that early change should be closely monitored in internet interventions, as early change may be an important indicator of treatment outcome. Study II (Chapter 6) picked up on the idea of analyzing change patterns in internet interventions and extended it by using the Muthen-Roy model to identify change-dropout patterns. A sligthly bigger sample of the dataset from Study I was analyzed (N = 483). Four change-dropout patterns emerged; high risk of dropout was associated with rapid improvement and deterioration. These findings indicate that clinicians should consider how dropout may depend on patient characteristics as well as symptom change, as dropout is associated with both deterioration and a good enough dosage of treatment. Study III (Chapter 7) compared adherence and outcome in different participant groups and investigated the impact of adherence to treatment components on treatment outcome in an internet intervention targeting anxiety symptoms. 50 outpatient participants waiting for face- to-face treatment and 37 self-referred participants were compared regarding adherence to treatment components and outcome. In addition, outpatient participants were compared to a matched sample of outpatients, who had no access to the internet intervention during the waiting period. Adherence to treatment components was investigated as a predictor of treatment outcome. Results suggested that especially adherence may vary depending on participant group. Also using specific measures of adherence such as adherence to treatment components may be crucial to detect change mechanisms in internet interventions. Fostering adherence to treatment components in participants may increase the effectiveness of internet interventions. Results of the three studies are discussed and general conclusions are drawn. Implications for future research as well as their utility for clinical practice and decision- making are presented.

Die publikationsbasierte Dissertation untersucht die Bedeutung sozialer Bewegungen für die Entwicklung der Sozialen Arbeit am Ende des 19. und den ersten Jahrzehnten des 20. Jahrhunderts als Profession und Disziplin in den USA und in Deutschland. Dabei wird die entstehende Soziale Arbeit als ‚Formbildung‘ sozialer Bewegungen verstanden und gefragt, wie sich die Bewegungen in die sich etablierende und institutionalisierende Profession und Wissenschaft Soziale Arbeit einschreiben, welche Anliegen dabei verfolgt werden und wie dadurch Wissen in der Sozialen Arbeit auch über nationalstaatliche Grenzen hinweg zirkuliert. Die Untersuchung konzentriert sich auf Prozesse der Pädagogisierung, also unterschiedliche ‚Formbildungen des Pädagogischen‘, die die Bewegungsanliegen zum Thema von Aufklärung, (Selbst)Bildung und Pädagogik machen, und auf solche der Verwissenschaftlichung, die sich auf den Aufbau einer Wissensgrundlage zur Bearbeitung von sozialen Problemen richten und dabei alternative Formen der Wissensproduktion ausbilden. Diese Prozesse werden in drei Teilstudien – zur Charity Organization Movement und der Settlement House Movement in den USA sowie der bürgerlichen Frauenbewegung in Deutschland – in sieben Einzelbeiträgen näher untersucht. Im Mittelpunkt stehen dabei die Handlungsmethoden und das Praxisverständnis sowie Forschungskonzepte und –projekte exemplarisch ausgewählter sozialbewegter Initiativen der Sozialen Arbeit. Dabei werden unter anderem nicht-intendierte Effekte untersucht, die zum Beispiel in Konservierungen normativer Vorstellungen und Ideologien in als demokratisierend angelegten Ansätzen, aber auch in ‚differenzverstärkenden‘ Effekten bestehen können.

A huge number of clinical studies and meta-analyses have shown that psychotherapy is effective on average. However, not every patient profits from psychotherapy and some patients even deteriorate in treatment. Due to this result and the restricted generalization of clinical studies to clinical practice, a more patient-focused research strategy has emerged. The question whether a particular treatment works for an individual case is the focus of this paradigm. The use of repeated assessments and the feedback of this information to therapists is a major ingredient of patient-focused research. Improving patient outcomes and reducing dropout rates by the use of psychometric feedback seems to be a promising path. Therapists seem to differ in the degree to which they make use of and profit from such feedback systems. This dissertation aims to better understand therapist differences in the context of patient-focused research and the impact of therapists on psychotherapy. Three different studies are included, which focus on different aspects within the field: Study I (Chapter 5) investigated how therapists use psychometric feedback in their work with patients and how much therapists differ in their usage. Data from 72 therapists treating 648 patients were analyzed. It could be shown that therapists used the psychometric feedback for most of their patients. Substantial variance in the use of feedback (between 27% and 52%) was attributable to therapists. Therapists were more likely to use feedback when they reported being satisfied with the graphical information they received. The results therefore indicated that not only patient characteristics or treatment progress affected the use of feedback. Study II (Chapter 6) picked up on the idea of analyzing systematic differences in therapists and applied it to the criterion of premature treatment termination (dropout). To answer the question whether therapist effects occur in terms of patients’ dropout rates, data from 707 patients treated by 66 therapists were investigated. It was shown that approximately six percent of variance in dropout rates could be attributed to therapists, even when initial impairment was controlled for. Other predictors of dropout were initial impairment, sex, education, personality styles, and treatment expectations. Study III (Chapter 7) extends the dissertation by investigating the impact of a transfer from one therapist to another within ongoing treatments. Data from 124 patients who agreed to and experienced a transfer during their treatment were analyzed. A significant drop in patient-rated as well as therapist-rated alliance levels could be observed after a transfer. On average, there seemed to be no difficulties establishing a good therapeutic alliance with the new therapist, although differences between patients were observed. There was no increase in symptom severity due to therapy transfer. Various predictors of alliance and symptom development after transfer were investigated. Impacts on clinical practice were discussed. Results of the three studies are discussed and general conclusions are drawn. Implications for future research as well as their utility for clinical practice and decision-making are presented.

Academic achievement is a central outcome in educational research, both in and outside higher education, has direct effects on individual’s professional and financial prospects and a high individual and public return on investment. Theories comprise cognitive as well as non-cognitive influences on achievement. Two examples frequently investigated in empirical research are knowledge (as a cognitive determinant) and stress (as a non-cognitive determinant) of achievement. However, knowledge and stress are not stable, what raises questions as to how temporal dynamics in knowledge on the one hand and stress on the other contribute to achievement. To study these contributions in the present doctoral dissertation, I used meta-analysis, latent profile transition analysis, and latent state-trait analysis. The results support the idea of knowledge acquisition as a cumulative and long-term process that forms the basis for academic achievement and conceptual change as an important mechanism for the acquisition of knowledge in higher education. Moreover, the findings suggest that students’ stress experiences in higher education are subject to stable, trait-like influences, as well as situational and/or interactional, state-like influences which are differentially related to achievement and health. The results imply that investigating the causal networks between knowledge, stress, and academic achievement is a promising strategy for better understanding academic achievement in higher education. For this purpose, future studies should use longitudinal designs, randomized controlled trials, and meta-analytical techniques. Potential practical applications include taking account of students’ prior knowledge in higher education teaching and decreasing stress among higher education students.

Early life adversity (ELA) poses a high risk for developing major health problems in adulthood including cardiovascular and infectious diseases and mental illness. However, the fact that ELA-associated disorders first become manifest many years after exposure raises questions about the mechanisms underlying their etiology. This thesis focuses on the impact of ELA on startle reflexivity, physiological stress reactivity and immunology in adulthood. The first experiment investigated the impact of parental divorce on affective processing. A special block design of the affective startle modulation paradigm revealed blunted startle responsiveness during presentation of aversive stimuli in participants with experience of parental divorce. Nurture context potentiated startle in these participants suggesting that visual cues of childhood-related content activates protective behavioral responses. The findings provide evidence for the view that parental divorce leads to altered processing of affective context information in early adulthood. A second investigation was conducted to examine the link between aging of the immune system and long-term consequences of ELA. In a cohort of healthy young adults, who were institutionalized early in life and subsequently adopted, higher levels of T cell senescence were observed compared to parent-reared controls. Furthermore, the results suggest that ELA increases the risk of cytomegalovirus infection in early childhood, thereby mediating the effect of ELA on T cell-specific immunosenescence. The third study addresses the effect of ELA on stress reactivity. An extended version of the Cold Pressor Test combined with a cognitive challenging task revealed blunted endocrine response in adults with a history of adoption while cardiovascular stress reactivity was similar to control participants. This pattern of response separation may best be explained by selective enhancement of central feedback-sensitivity to glucocorticoids resulting from ELA, in spite of preserved cardiovascular/autonomic stress reactivity.