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Internet interventions have gained popularity and the idea is to use them to increase the availability of psychological treatment. Research suggests that internet interventions are effective for a number of psychological disorders with effect sizes comparable to those found in face-to-face treatment. However, when provided as an add-on to treatment as usual, internet interventions do not seem to provide additional benefit. Furthermore, adherence and dropout rates vary greatly between studies, limiting the generalizability of the findings. This underlines the need to further investigate differences between internet interventions, participating patients, and their usage of interventions. A stronger focus on the processes of change seems necessary to better understand the varying findings regarding outcome, adherence and dropout in internet interventions. Thus, the aim of this dissertation was to investigate change processes in internet interventions and the factors that impact treatment response. This could help to identify important variables that should be considered in research on internet interventions as well as in clinical settings that make use of internet interventions.
Study I (Chapter 5) investigated early change patterns in participants of an internet intervention targeting depression. Data from 409 participants were analyzed using Growth Mixture Modeling. Specifically a piecewise model was applied to model change from screening to registration (pretreatment) and early change (registration to week four of treatment). Three early change patterns were identified; two were characterized by improvement and one by deterioration. The patterns were predictive of treatment outcome. The results therefore indicated that early change should be closely monitored in internet interventions, as early change may be an important indicator of treatment outcome.
Study II (Chapter 6) picked up on the idea of analyzing change patterns in internet interventions and extended it by using the Muthen-Roy model to identify change-dropout patterns. A sligthly bigger sample of the dataset from Study I was analyzed (N = 483). Four change-dropout patterns emerged; high risk of dropout was associated with rapid improvement and deterioration. These findings indicate that clinicians should consider how dropout may depend on patient characteristics as well as symptom change, as dropout is associated with both deterioration and a good enough dosage of treatment.
Study III (Chapter 7) compared adherence and outcome in different participant groups and investigated the impact of adherence to treatment components on treatment outcome in an internet intervention targeting anxiety symptoms. 50 outpatient participants waiting for face- to-face treatment and 37 self-referred participants were compared regarding adherence to treatment components and outcome. In addition, outpatient participants were compared to a matched sample of outpatients, who had no access to the internet intervention during the waiting period. Adherence to treatment components was investigated as a predictor of treatment outcome. Results suggested that especially adherence may vary depending on participant group. Also using specific measures of adherence such as adherence to treatment components may be crucial to detect change mechanisms in internet interventions. Fostering adherence to treatment components in participants may increase the effectiveness of internet interventions.
Results of the three studies are discussed and general conclusions are drawn.
Implications for future research as well as their utility for clinical practice and decision- making are presented.
Stress gilt als zentrales Gesundheitsrisiko des 21. Jahrhunderts und wird in der Forschung als multidimensionales Konstrukt auf psychologischer und biologischer Ebene untersucht. Wäh-rend die subjektive Wahrnehmung von Stress nicht mit der biologischen Stressreaktivität zu-sammenhängen muss, ist der negative Einfluss stressassoziierter biologischer Prozesse auf Wohlbefinden und Gesundheit gut belegt. Bereits im Grundschulalter zeigen Kinder eine mit Erwachsenen vergleichbare Stressbelastung und gesundheitliche Folgen, Bewältigungsstrategien sind in diesem Alter allerdings noch nicht vollständig entwickelt. Präventionsprogramme im Grundschulalter sollen Kinder in ihren sich entwickelnden Stressbewältigungsfähigkeiten fördern, wobei sowohl emotionsfokussierte und problemorientierte Ansätze als auch soziale Unterstützung wichtige Faktoren darstellen könnten.
Das einleitende Literatur-Review evaluiert bisherige Stresspräventionsstudien und verdeutlicht, dass zwar die Wirksamkeit und Anwendbarkeit von mehrfaktoriellen Stresspräventionsprogrammen im Rahmen psychometrischer Erhebungen gezeigt werden konnten, biologische Prozesse in der Forschung bisher allerdings nicht erhoben und außer Acht gelassen wurden.
Die empirische Untersuchung in Studie 1 zeigt, dass eine multidimensionale psychobiologische Betrachtungsweise sinnvoll ist, indem sowohl die Psychometrie, als auch psychobiologische Prozesse der Stressreaktion miteinbezogen und die Auswirkungen von Stressprävention auf den verschiedenen Ebenen untersucht wurden. Zwei Kurzinterventionen wurden dazu miteinander verglichen und ihre Wirkung auf psychophysiologischen Ebenen (z.B. Kortisol, α-Amylase und Herzrate) in einem Prä-Post Design geprüft. Eine statistisch signifikante Abnahme psychophysiologischer Stressreaktivität, sowie stressassoziierter psychologischer Symptome verdeutlichte die multidimensionale Wirksamkeit von Stressmanagementtrainings.
Studie 2 wurde im Rahmen der Covid-19-Pandemie entworfen. Die in Studie 1 trainierten Kinder wurden mittels Online-Fragebogenerhebung mit einer Kontrollgruppe hinsichtlich ihrer Stressbelastung verglichen. Die Ergebnisse zeigten eine geringere Belastung und vermehrte günstige Bewältigungsstrategien trainierter Kinder im Vergleich zur Kontrollgruppe.
Diese Ergebnisse heben die Relevanz einer multidimensionalen Betrachtung kindlichen Stresses hervor. Es wurde gezeigt, dass Stresspräventionsprogramme auf den unterschiedlichen Ebenen der Stressreaktion wirken und sogar in gesamtgesellschaftlichen Krisensituationen stresspro-tektiv wirken können. Zukünftige Studien sollten Stresspräventionen im Grundschulalter psychophysiologisch evaluieren und deren Wirkung in Längsschnittstudien beurteilen, um das Verständnis der zugrundeliegenden Mechanismen zu verbessern.
Evidence points to autonomy as having a place next to affiliation, achievement, and power as one of the basic implicit motives; however, there is still some research that needs to be conducted to support this notion.
The research in this dissertation aimed to address this issue. I have specifically focused on two issues that help solidify the foundation of work that has already been conducted on the implicit autonomy motive, and will also be a foundation for future studies. The first issue is measurement. Implicit motives should be measured using causally valid instruments (McClelland, 1980). The second issue addresses the function of motives. Implicit motives orient, select, and energize behavior (McClelland, 1980). If autonomy is an implicit motive, then we need a valid instrument to measure it and we also need to show that it orients, selects, and energizes behavior.
In the following dissertation, I address these two issues in a series of ten studies. Firstly, I present studies that examine the causal validity of the Operant Motive Test (OMT; Kuhl, 2013) for the implicit affiliation and power motives using established methods. Secondly, I developed and empirically tested pictures to specifically assess the implicit autonomy motive and examined their causal validity. Thereafter, I present two studies that investigated the orienting and energizing effects of the implicit autonomy motive. The results of the studies solidified the foundation of the OMT and how it measures nAutonomy. Furthermore, this dissertation demonstrates that nAutonomy fulfills the criteria for two of the main functions of implicit motives. Taken together, the findings of this dissertation provide further support for autonomy as an implicit motive and a foundation for intriguing future studies.
There is no longer any doubt about the general effectiveness of psychotherapy. However, up to 40% of patients do not respond to treatment. Despite efforts to develop new treatments, overall effectiveness has not improved. Consequently, practice-oriented research has emerged to make research results more relevant to practitioners. Within this context, patient-focused research (PFR) focuses on the question of whether a particular treatment works for a specific patient. Finally, PFR gave rise to the precision mental health research movement that is trying to tailor treatments to individual patients by making data-driven and algorithm-based predictions. These predictions are intended to support therapists in their clinical decisions, such as the selection of treatment strategies and adaptation of treatment. The present work summarizes three studies that aim to generate different prediction models for treatment personalization that can be applied to practice. The goal of Study I was to develop a model for dropout prediction using data assessed prior to the first session (N = 2543). The usefulness of various machine learning (ML) algorithms and ensembles was assessed. The best model was an ensemble utilizing random forest and nearest neighbor modeling. It significantly outperformed generalized linear modeling, correctly identifying 63.4% of all cases and uncovering seven key predictors. The findings illustrated the potential of ML to enhance dropout predictions, but also highlighted that not all ML algorithms are equally suitable for this purpose. Study II utilized Study I’s findings to enhance the prediction of dropout rates. Data from the initial two sessions and observer ratings of therapist interventions and skills were employed to develop a model using an elastic net (EN) algorithm. The findings demonstrated that the model was significantly more effective at predicting dropout when using observer ratings with a Cohen’s d of up to .65 and more effective than the model in Study I, despite the smaller sample (N = 259). These results indicated that generating models could be improved by employing various data sources, which provide better foundations for model development. Finally, Study III generated a model to predict therapy outcome after a sudden gain (SG) in order to identify crucial predictors of the upward spiral. EN was used to generate the model using data from 794 cases that experienced a SG. A control group of the same size was also used to quantify and relativize the identified predictors by their general influence on therapy outcomes. The results indicated that there are seven key predictors that have varying effect sizes on therapy outcome, with Cohen's d ranging from 1.08 to 12.48. The findings suggested that a directive approach is more likely to lead to better outcomes after an SG, and that alliance ruptures can be effectively compensated for. However, these effects
were reversed in the control group. The results of the three studies are discussed regarding their usefulness to support clinical decision-making and their implications for the implementation of precision mental health.
With the advent of highthroughput sequencing (HTS), profiling immunoglobulin (IG) repertoires has become an essential part of immunological research. The dissection of IG repertoires promises to transform our understanding of the adaptive immune system dynamics. Advances in sequencing technology now also allow the use of the Ion Torrent Personal Genome Machine (PGM) to cover the full length of IG mRNA transcripts. The applications of this benchtop scale HTS platform range from identification of new therapeutic antibodies to the deconvolution of malignant B cell tumors. In the context of this thesis, the usability of the PGM is assessed to investigate the IG heavy chain (IGH) repertoires of animal models. First, an innovate bioinformatics approach is presented to identify antigendriven IGH sequences from bulk sequenced bone marrow samples of transgenic humanized rats, expressing a human IG repertoire (OmniRatTM). We show, that these rats mount a convergent IGH CDR3 response towards measles virus hemagglutinin protein and tetanus toxoid, with high similarity to human counterparts. In the future, databases could contain all IGH CDR3 sequences with known specificity to mine IG repertoire datasets for past antigen exposures, ultimately reconstructing the immunological history of an individual. Second, a unique molecular identifier (UID) based HTS approach and network property analysis is used to characterize the CLLlike CD5+ B cell expansion of A20BKO mice overexpressing a natural short splice variant of the CYLD gene (A20BKOsCYLDBOE). We could determine, that in these mice, overexpression of sCYLD leads to unmutated subvariant of CLL (UCLL). Furthermore, we found that this short splice variant is also seen in human CLL patients highlighting it as important target for future investigations. Third, the UID based HTS approach is improved by adapting it to the PGM sequencing technology and applying a custommade data processing pipeline including the ImMunoGeneTics (IMGT) database error detection. Like this, we were able to obtain correct IGH sequences with over 99.5% confidence and correct CDR3 sequences with over 99.9% confidence. Taken together, the results, protocols and sample processing strategies described in this thesis will improve the usability of animal models and the Ion Torrent PGM HTS platform in the field if IG repertoire research.
Knowledge acquisition comprises various processes. Each of those has its dedicated research domain. Two examples are the relations between knowledge types and the influences of person-related variables. Furthermore, the transfer of knowledge is another crucial domain in educational research. I investigated these three processes through secondary analyses in this dissertation. Secondary analyses comply with the broadness of each field and yield the possibility of more general interpretations. The dissertation includes three meta-analyses: The first meta-analysis reports findings on the predictive relations between conceptual and procedural knowledge in mathematics in a cross-lagged panel model. The second meta-analysis focuses on the mediating effects of motivational constructs on the relationship between prior knowledge and knowledge after learning. The third meta-analysis deals with the effect of instructional methods in transfer interventions on knowledge transfer in school students. These three studies provide insights into the determinants and processes of knowledge acquisition and transfer. Knowledge types are interrelated; motivation mediates the relation between prior and later knowledge, and interventions influence knowledge transfer. The results are discussed by examining six key insights that build upon the three studies. Additionally, practical implications, as well as methodological and content-related ideas for further research, are provided.
In light of an alarming increase of sick leave and early retirement because of mental diseases, the public, political and scientific interest in an effective protection of psychological health within organizational context has been increasing for years. More and more the focus is especially on executives who influence the mental health of their employees by leadership behavior within interactions and by designing work tasks and working pro-cesses. In this regard classical and modern, explicit health-oriented leadership approaches provide valuable insights but also neglect the important influence of leadership situation on health-oriented leadership. This situation reduces the explanatory and predictive potential of available health-oriented leadership concepts.
In article 1 a conceptual framework model called Systemic Salutogenic Interaction Model (SSIM) is developed and justified that is based on findings of evidence-based leadership research but also integrates systemic concepts and key elements of the theory of saluto-genesis. The SSIM distinguishes between two levels: Within the primary system of salutogenic interaction salutogenic leadership and employees behavior for the first time are conceptualized as recipocal influence factors that influence each other (level 1). The organizational context is explicitly taken into account as significant factor outside the primary system that effects the behavior of both interaction partners mediated via cognitive pro-cesses (level 2). Due to this focus on interactions und context factors for the first time leadership situation becomes an explicit component of a health-oriented leadership concept.
First of all, article 2 focusses on the systematic analysis of the relative importance health related leadership aspects. For this purpose the TIMP-inventory was developed that records three distinct core-factors of salutogenic leadership (trust, incident management and pressure) which explain more variance of the Work-SoC construct than established general approaches and health-related leadership concepts.
In article 3 the results of a cross-sectional multilevel analysis indicate that the perceived leadership situation significantly explains variance of salutogenic leadership between teams. For the first time, this shows a significant correlation between specific aspects of leadership situation und salutogenic leadership behavior.
Within the frame of a quasi-experimental study (article 4), for the first time, a correlation is shown between salutogenic target-setting processes on executive’s side and the Work-SoC of team members. These results support an essential effect mechanism that is postulated in the SSIM. Furthermore these findings indicate that the SSIM can profitably be used within the context of salutogenic coachings, underlining its practical benefit.
Taken together the empirical findings of this dissertation support the assumption that the new SSIM approach significantly expands the explanatory und predictive potential of the health-oriented leadership concepts so far available. The results also raise a number of new, interesting questions for future research. Furthermore the SSIM broadens the perspective regarding the strategic orientation of human resource and organizational devel-opment. Especially out of the SSIM important guiding principles and innovative concepts for a target-oriented diagnostic und effective interventions can be derived. Thus this dissertation lays the foundation for a coherent, holistic oriented salutogenic leadership research und practice.
Academic achievement is a central outcome in educational research, both in and outside higher education, has direct effects on individual’s professional and financial prospects and a high individual and public return on investment. Theories comprise cognitive as well as non-cognitive influences on achievement. Two examples frequently investigated in empirical research are knowledge (as a cognitive determinant) and stress (as a non-cognitive determinant) of achievement. However, knowledge and stress are not stable, what raises questions as to how temporal dynamics in knowledge on the one hand and stress on the other contribute to achievement. To study these contributions in the present doctoral dissertation, I used meta-analysis, latent profile transition analysis, and latent state-trait analysis. The results support the idea of knowledge acquisition as a cumulative and long-term process that forms the basis for academic achievement and conceptual change as an important mechanism for the acquisition of knowledge in higher education. Moreover, the findings suggest that students’ stress experiences in higher education are subject to stable, trait-like influences, as well as situational and/or interactional, state-like influences which are differentially related to achievement and health. The results imply that investigating the causal networks between knowledge, stress, and academic achievement is a promising strategy for better understanding academic achievement in higher education. For this purpose, future studies should use longitudinal designs, randomized controlled trials, and meta-analytical techniques. Potential practical applications include taking account of students’ prior knowledge in higher education teaching and decreasing stress among higher education students.
Ein positiver Zusammenhang von Leistungsmotivation, Flow und Wohlbefinden ist in Einzelpfaden gut belegt. Befunde, welche alle drei Variablen miteinander in Beziehung setzen, stehen in der Bildungsfor-schung noch aus. Ziel dieser Arbeit ist es, den Einfluss einzelner Dimensionen von Leistungsmotivation & Flow auf das subjektive Wohlempfinden von Schüler/innen, unter Berücksichtigung etwaiger Media-tionseffekte durch Flow zu untersuchen. Die Grundlage der Daten bildet der erste Messzeitpunkt einer motivationsbezogenen Interventionsstudie.
Erhoben wurden die Daten im Rahmen einer prospektiven randomisierten Längsschnittstudie im Kon-trollgruppendesign (N=742; 46,2% weibl.), welche mit Schüler/innen von sieben rheinland-pfälzischen Schulen durchgeführt wurde. Leistungsmotivation, Wohlbefinden und Flow wurden mit folgenden In-strumenten erfasst: Petermann & Winkel (2007a&b): Fragebogen zur Leistungsmotivation; Flow-Skala (in Anlehnung an Rheinberg et al., 2003); Flourishing-Skala (in Anlehnung an Diener et al., 2009). Ausge-wertet wurden die Daten mittels Mediatoranalysen per multipler Regression mit SPSS.
Die Ergebnisse multipler Regressionsanalysen konnten sowohl in der Primar-, als auch Sekundarstufe direkte Effekte einzelner Leistungsmotivationsskalen auf das subjektive Wohlbefinden belegen. Zudem wurden in den Jahrgansstufen 2&3,4&5,7&9 der Zusammenhang zwischen Leistungsmotivation und Wohlbefinden durch Flow-Erleben mediiert. In der Jahrgangsstufe 11 konnte kein Mediationseffekt gefunden werden.
Die Ergebnisse bestätigen vorliegende Korrelationsstudien und identifizieren Flow als einen zentralen Mediator zwischen der Leistungsmotivation und dem Wohlbefinden bei Schüler/innen. Die Reflexion dieser Befunde eröffnet großes Potential für die weitere Ausarbeitung und Implementierung Flow-förderlicher Interaktionen in der Schule.
The present dissertation was developed to emphasize the importance of self-regulatory abilities and to derive novel opportunities to empower self-regulation. From the perspective of PSI (Personality Systems Interactions) theory (Kuhl, 2001), interindividual differences in self-regulation (action vs. state orientation) and their underlying mechanisms are examined in detail. Based on these insights, target-oriented interventions are derived, developed, and scientifically evaluated. The present work comprises a total of four studies which, on the one hand, highlight the advantages of a good self-regulation (e.g., enacting difficult intentions under demands; relation with prosocial power motive enactment and well-being). On the other hand, mental contrasting (Oettingen et al., 2001), an established self-regulation method, is examined from a PSI perspective and evaluated as a method to support individuals that struggle with self-regulatory deficits. Further, derived from PSI theory`s assumptions, I developed and evaluated a novel method (affective shifting) that aims to support individuals in overcoming self-regulatory deficits. Thereby affective shifting supports the decisive changes in positive affect for successful intention enactment (Baumann & Scheffer, 2010). The results of the present dissertation show that self-regulated changes between high and low positive affect are crucial for efficient intention enactment and that methods such as mental contrasting and affective shifting can empower self-regulation to support individuals to successfully close the gap between intention and action.
When humans encounter attitude objects (e.g., other people, objects, or constructs), they evaluate them. Often, these evaluations are based on attitudes. Whereas most research focuses on univalent (i.e., only positive or only negative) attitude formation, little research exists on ambivalent (i.e., simultaneously positive and negative) attitude formation. Following a general introduction into ambivalence, I present three original manuscripts investigating ambivalent attitude formation. The first manuscript addresses ambivalent attitude formation from previously univalent attitudes. The results indicate that responding to a univalent attitude object incongruently leads to ambivalence measured via mouse tracking but not ambivalence measured via self-report. The second manuscript addresses whether the same number of positive and negative statements presented block-wise in an impression formation task leads to ambivalence. The third manuscript also used an impression formation task and addresses the question of whether randomly presenting the same number of positive and negative statements leads to ambivalence. Additionally, the effect of block size of the same valent statements is investigated. The results of the last two manuscripts indicate that presenting all statements of one valence and then all statements of the opposite valence leads to ambivalence measured via self-report and mouse tracking. Finally, I discuss implications for attitude theory and research as well as future research directions.
Early life adversity (ELA) poses a high risk for developing major health problems in adulthood including cardiovascular and infectious diseases and mental illness. However, the fact that ELA-associated disorders first become manifest many years after exposure raises questions about the mechanisms underlying their etiology. This thesis focuses on the impact of ELA on startle reflexivity, physiological stress reactivity and immunology in adulthood.
The first experiment investigated the impact of parental divorce on affective processing. A special block design of the affective startle modulation paradigm revealed blunted startle responsiveness during presentation of aversive stimuli in participants with experience of parental divorce. Nurture context potentiated startle in these participants suggesting that visual cues of childhood-related content activates protective behavioral responses. The findings provide evidence for the view that parental divorce leads to altered processing of affective context information in early adulthood.
A second investigation was conducted to examine the link between aging of the immune system and long-term consequences of ELA. In a cohort of healthy young adults, who were institutionalized early in life and subsequently adopted, higher levels of T cell senescence were observed compared to parent-reared controls. Furthermore, the results suggest that ELA increases the risk of cytomegalovirus infection in early childhood, thereby mediating the effect of ELA on T cell-specific immunosenescence.
The third study addresses the effect of ELA on stress reactivity. An extended version of the Cold Pressor Test combined with a cognitive challenging task revealed blunted endocrine response in adults with a history of adoption while cardiovascular stress reactivity was similar to control participants. This pattern of response separation may best be explained by selective enhancement of central feedback-sensitivity to glucocorticoids resulting from ELA, in spite of preserved cardiovascular/autonomic stress reactivity.
Why they rebel peacefully: On the violence-reducing effects of a positive attitude towards democracy
Under the impression of Europe’s drift into Nazism and Stalinism in the first half of the 20th century, social psychological research has focused strongly on dangers inherent in people’s attachment to a political system. The dissertation at hand contributes to a more differentiated perspective by examining violence-reducing aspects of political system attachment in four consecutive steps: First, it highlights attachment to a social group as a resource for violence prevention on an intergroup level. The results suggest that group attachment fosters self-control, a well-known protective factor against violence. Second, it demonstrates violence-reducing influences of attachment on a societal level. The findings indicate that attachment to a democracy facilitate peaceful and prevent violent protest tendencies. Third, it introduces the concept of political loyalty, defined as a positive attitude towards democracy, in order to clarify the different approaches of political system attachment. A set of three studies show the reliability and validity of a newly developed political loyalty questionnaire that distinguishes between affective and cognitive aspects. Finally, the dissertation differentiates former findings with regard to protest tendencies using the concept of political loyalty. A set of two experiments show that affective rather than cognitive aspects of political loyalty instigate peaceful protest tendencies and prevent violent ones. Implications of this dissertation for political engagement and peacebuilding as well as avenues for future research are discussed.
Im Rahmen psychologischer Wissenschaftskommunikation werden Plain Language Summaries (PLS, Kerwer et al., 2021) zunehmend bedeutsamer. Es handelt sich hierbei um
zugängliche, überblicksartige Zusammenfassungen, welche das Verständnis von Lai:innen
potenziell unterstützen und ihr Vertrauen in wissenschaftliche Forschung fördern können.
Dies erscheint speziell vor dem Hintergrund der Replikationskrise (Wingen et al., 2019) sowie Fehlinformationen in Online-Kontexten (Swire-Thompson & Lazer, 2020) relevant. Die
positiven Auswirkungen zweier Effekte auf Vertrauen sowie ihre mögliche Interaktion fanden im Kontext von PLS bisher kaum Berücksichtigung: Zum einen die einfache Darstellung von Informationen (Easiness-Effekt, Scharrer et al., 2012), zum anderen ein möglichst wissenschaftlicher Stil (Scientificness-Effekt, Thomm & Bromme, 2012). Diese Dissertation hat zum Ziel, im Kontext psychologischer PLS genauere Bestandteile beider Effekte zu identifizieren und den Einfluss von Einfachheit und Wissenschaftlichkeit auf Vertrauen zu beleuchten. Dazu werden drei Artikel zu präregistrierten Online-Studien mit deutschsprachigen Stichproben vorgestellt.
Im ersten Artikel wurden in zwei Studien verschiedene Textelemente psychologischer PLS systematisch variiert. Es konnte ein signifikanter Einfluss von Fachtermini, Informationen zur
Operationalisierung, Statistiken und dem Grad an Strukturierung auf die von Lai:innen berichtete Einfachheit der PLS beobachtet werden. Darauf aufbauend wurden im zweiten Artikel vier PLS, die von Peer-Review-Arbeiten abgeleitet wurden, in ihrer Einfachheit und
Wissenschaftlichkeit variiert und Lai:innen zu ihrem Vertrauen in die Texte und Autor:innen befragt. Hier ergab sich zunächst nur ein positiver Einfluss von Wissenschaftlichkeit auf
Vertrauen, während der Easiness-Effekt entgegen der Hypothesen ausblieb. Exploratorische Analysen legten jedoch einen positiven Einfluss der von Lai:innen subjektiv wahrgenommenen Einfachheit auf ihr Vertrauen sowie eine signifikante Interaktion mit der
wahrgenommenen Wissenschaftlichkeit nahe. Diese Befunde lassen eine vermittelnde Rolle der subjektiven Wahrnehmung von Lai:innen für beide Effekte vermuten. Im letzten Artikel
wurde diese Hypothese über Mediationsanalysen geprüft. Erneut wurden zwei PLS
präsentiert und sowohl die Wissenschaftlichkeit des Textes als auch die der Autor:in manipuliert. Der Einfluss höherer Wissenschaftlichkeit auf Vertrauen wurde durch die
subjektiv von Lai:innen wahrgenommene Wissenschaftlichkeit mediiert. Zudem konnten
dimensionsübergreifende Mediationseffekte beobachtet werden.
Damit trägt diese Arbeit über bestehende Forschung hinaus zur Klärung von Rahmenbedingungen des Easiness- und Scientificness-Effektes bei. Theoretische
Implikationen zur zukünftigen Definition von Einfachheit und Wissenschaftlichkeit, sowie
praktische Konsequenzen hinsichtlich unterschiedlicher Zielgruppen von
Wissenschaftskommunikation und dem Einfluss von PLS auf die Entscheidungsbildung von
Lai:innen werden diskutiert.
Auf der Grundlage einer Fragebogenstudie wurden unterschiedliche Elemente eines förderlichen Umgangs mit Gesundheitsinformationen betrachtet und ihre Zusammenhänge mit personspezifischen Merkmalen analysiert. Als zentrale Aspekte der Informationsprozesse wurden die drei Elemente Gesundheitsinformationskompetenz, Gesundheitsinteresse und gesundheitsspezifische Informationsgewohnheiten konzeptuell voneinander getrennt. Auf der Basis des bisherigen Forschungsstands wurde zunächst ein theoretisches Modell des Umgangs mit Gesundheitsinformationen entwickelt, das die Bedeutung der Kompetenz und des Interesses für gesundheitsbezogene Informationsgewohnheiten hervorhebt, individuelle Ausprägungen dieser drei Elemente mit soziodemografischen Faktoren, Persönlichkeitseigenschaften, Überzeugungen und dem Gesundheitszustand in Beziehung setzt sowie Verbindungen zu gesundheitsrelevanten Verhaltensweisen beschreibt. Dieses Modell wurde anschließend an einer Stichprobe von 352 Berufsschülerinnen und -schülern aus drei Berufsbereichen (Wirtschaft/Verwaltung, Technik und Gesundheit) empirisch überprüft. Über multiple Regressionsanalysen wurden bedeutsame Prädiktoren für die drei Hauptelemente Kompetenz, Interesse und Informationsgewohnheiten identifiziert, über logistische Regressionen und Korrelationen ihre Zusammenhänge mit dem Gesundheitsverhalten überprüft. Darüber hinaus wurden lineare Strukturgleichungsmodelle zur Vorhersage des Informationsverhaltens entwickelt. Die Ergebnisse bestätigen die konzeptionelle Trennung der drei Faktoren, die jeweils mit unterschiedlichen Prädiktoren verbunden waren. Auf der Basis der Befunde werden Ansatzpunkte für die weitere Forschung und die Förderung eines kompetenten Umgangs mit Gesundheitsinformationen diskutiert.
Die publikationsbasierte Dissertation untersucht die Bedeutung sozialer Bewegungen für die Entwicklung der Sozialen Arbeit am Ende des 19. und den ersten Jahrzehnten des 20. Jahrhunderts als Profession und Disziplin in den USA und in Deutschland. Dabei wird die entstehende Soziale Arbeit als ‚Formbildung‘ sozialer Bewegungen verstanden und gefragt, wie sich die Bewegungen in die sich etablierende und institutionalisierende Profession und Wissenschaft Soziale Arbeit einschreiben, welche Anliegen dabei verfolgt werden und wie dadurch Wissen in der Sozialen Arbeit auch über nationalstaatliche Grenzen hinweg zirkuliert.
Die Untersuchung konzentriert sich auf Prozesse der Pädagogisierung, also unterschiedliche ‚Formbildungen des Pädagogischen‘, die die Bewegungsanliegen zum Thema von Aufklärung, (Selbst)Bildung und Pädagogik machen, und auf solche der Verwissenschaftlichung, die sich auf den Aufbau einer Wissensgrundlage zur Bearbeitung von sozialen Problemen richten und dabei alternative Formen der Wissensproduktion ausbilden. Diese Prozesse werden in drei Teilstudien – zur Charity Organization Movement und der Settlement House Movement in den USA sowie der bürgerlichen Frauenbewegung in Deutschland – in sieben Einzelbeiträgen näher untersucht. Im Mittelpunkt stehen dabei die Handlungsmethoden und das Praxisverständnis sowie Forschungskonzepte und –projekte exemplarisch ausgewählter sozialbewegter Initiativen der Sozialen Arbeit. Dabei werden unter anderem nicht-intendierte Effekte untersucht, die zum Beispiel in Konservierungen normativer Vorstellungen und Ideologien in als demokratisierend angelegten Ansätzen, aber auch in ‚differenzverstärkenden‘ Effekten bestehen können.
Heterogenität ist Teil des (Schul-)Alltags, was sich in den Lerngruppen widerspiegelt, die Lehrkräfte in der Schule vorfinden. Unterschiedlichen Bedürfnissen auf Seiten der Schüler/-innenschaft soll – und das ist in zahlreichen der Öffentlichkeit zugänglichen Dokumenten, wie Schulgesetzen, Schulordnungen und Standards für die Lehrerbildung festgeschrieben – in Form von Differenzierung begegnet werden. Innerhalb dieser Dissertation wird untersucht, wie Binnendifferenzierung auf Mikroebene in der Schulpraxis implementiert wird. Dabei werden die Einsatzhäufigkeit binnendifferenzierender Maßnahmen und Kontextvariablen von Binnendifferenzierung untersucht. Anhand einer Stichprobe von N = 295 Lehrkräften verschiedener Schulformen, die die Fächer Deutsch und/oder Englisch unterrichten, wurde u.a. gezeigt, dass Binnendifferenzierung allgemein nicht (sehr) häufig eingesetzt wird, dass manche Maßnahmen häufiger Einsatz finden als andere, dass an Gymnasien Binnendifferenzierung nicht so häufig eingesetzt wird, wie an anderen Schulformen und dass die Einsatzhäufigkeit bedingende Kontextfaktoren bspw. kollegiale Zusammenarbeit bei der Unterrichtsplanung und -durchführung, die wahrgenommene Qualität der Lehramtsausbildung hinsichtlich des Umgangs mit Heterogenität und die Bereitschaft zur Implementation von Binnendifferenzierung sind und auch Einstellungen zu Binnendifferenzierung und (Lehrer/-innen)Selbstwirksamkeitserwartungen in Zusammenhang mit dem Maßnahmeneinsatz stehen. Die durchgeführte Post-hoc Analyse zeigte bzgl. Einsatzhäufigkeit weiterhin Zusammenhänge zwischen der Persönlichkeit der Lehrkräfte und der Schulform, an der diese unterrichten. Die Ergebnisse entstammen der Schulpraxis und liefern deshalb praktische Implikationen, wie bspw. Hinweise zur Steigerung der Qualität der Lehramtsausbildung, die neben zukünftigen Forschungsansätzen im Rahmen dieser Arbeit expliziert werden.
Hypothalamic-pituitary-adrenal (HPA) axis-related genetic variants influence the stress response
(2019)
The physiological stress system includes the hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic-adrenal-medullary system (SAM). Parameters representing these systems such as cortisol, blood pressure or heart rate define the physiological reaction in response to a stressor. The main objective of the studies described in this thesis was to understand the role of the HPA-related genetic factors in these two systems. Genetic factors represent one of the components causing individual variations in physiological stress parameters. Five genes involved in the functioning of the HPA axis regarding stress responses are examined in this thesis. They are: corticotropin-releasing hormone (CRH), the glucocorticoid receptor (GR), the mineralocorticoid receptor (MR), the 5-hydroxytryptamine-transporter-linked polymorphic region (5-HTTLPR) in the serotonin transporter (5-HTT) and the brain-derived neurotrophic factor (BDNF) gene. Two hundred thirty-two healthy participants were genotyped. The influence of genetic factors on physiological parameters, such as post-awakening cortisol and blood pressure was assessed, as well as the influence of genetic factors on stress reactivity in response to a socially evaluated cold pressor test (SeCPT). Three studies tested the HPA-related genes each on three different levels. The first study examined the influences of genotypes and haplotypes of these five genes on physiological as well as psychological stress indicators (Chapter 2). The second study examined the effects of GR variants (genotypes and haplotypes) and promoter methylation level on both the SAM system and the HPA axis stress reactivity (Chapter 3). The third study comprised the characterization of CRH promoter haplotypes in an in-vitro study and the association of the CRH promoter with stress indicators in vivo (Chapter 4).
The present work explores how theories of motivation can be used to enhance video game research. Currently, Flow-Theory and Self-Determination Theory are the most common approaches in the field of Human-Computer Interaction. The dissertation provides an in-depth look into Motive Disposition Theory and how to utilize it to explain interindividual differences in motivation. Different players have different preferences and make different choices when playing games, and not every player experiences the same outcomes when playing the same game. I provide a short overview of the current state of the research on motivation to play video games. Next, Motive Disposition Theory is applied in the context of digital games in four different research papers, featuring seven studies, totaling 1197 participants. The constructs of explicit and implicit motives are explained in detail while focusing on the two social motives (i.e., affiliation and power). As dependent variables, behaviour, preferences, choices, and experiences are used in different game environments (i.e., Minecraft, League of Legends, and Pokémon). The four papers are followed by a general discussion about the seven studies and Motive Disposition Theory in general. Finally, a short overview is provided about other theories of motivation and how they could be used to further our understanding of the motivation to play digital games in the future. This thesis proposes that 1) Motive Disposition Theory represents a valuable approach to understand individual motivations within the context of digital games; 2) there is a variety of motivational theories that can and should be utilized by researchers in the field of Human-Computer Interaction to broaden the currently one-sided perspective on human motivation; 3) researchers should aim to align their choice of motivational theory with their research goals by choosing the theory that best describes the phenomenon in question and by carefully adjusting each study design to the theoretical assumptions of that theory.