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The dissertation deals with methods to improve design-based and model-assisted estimation techniques for surveys in a finite population framework. The focus is on the development of the statistical methodology as well as their implementation by means of tailor-made numerical optimization strategies. In that regard, the developed methods aim at computing statistics for several potentially conflicting variables of interest at aggregated and disaggregated levels of the population on the basis of one single survey. The work can be divided into two main research questions, which are briefly explained in the following sections.
First, an optimal multivariate allocation method is developed taking into account several stratification levels. This approach results in a multi-objective optimization problem due to the simultaneous consideration of several variables of interest. In preparation for the numerical solution, several scalarization and standardization techniques are presented, which represent the different preferences of potential users. In addition, it is shown that by solving the problem scalarized with a weighted sum for all combinations of weights, the entire Pareto frontier of the original problem can be generated. By exploiting the special structure of the problem, the scalarized problems can be efficiently solved by a semismooth Newton method. In order to apply this numerical method to other scalarization techniques as well, an alternative approach is suggested, which traces the problem back to the weighted sum case. To address regional estimation quality requirements at multiple stratification levels, the potential use of upper bounds for regional variances is integrated into the method. In addition to restrictions on regional estimates, the method enables the consideration of box-constraints for the stratum-specific sample sizes, allowing minimum and maximum stratum-specific sampling fractions to be defined.
In addition to the allocation method, a generalized calibration method is developed, which is supposed to achieve coherent and efficient estimates at different stratification levels. The developed calibration method takes into account a very large number of benchmarks at different stratification levels, which may be obtained from different sources such as registers, paradata or other surveys using different estimation techniques. In order to incorporate the heterogeneous quality and the multitude of benchmarks, a relaxation of selected benchmarks is proposed. In that regard, predefined tolerances are assigned to problematic benchmarks at low aggregation levels in order to avoid an exact fulfillment. In addition, the generalized calibration method allows the use of box-constraints for the correction weights in order to avoid an extremely high variation of the weights. Furthermore, a variance estimation by means of a rescaling bootstrap is presented.
Both developed methods are analyzed and compared with existing methods in extensive simulation studies on the basis of a realistic synthetic data set of all households in Germany. Due to the similar requirements and objectives, both methods can be successively applied to a single survey in order to combine their efficiency advantages. In addition, both methods can be solved in a time-efficient manner using very comparable optimization approaches. These are based on transformations of the optimality conditions. The dimension of the resulting system of equations is ultimately independent of the dimension of the original problem, which enables the application even for very large problem instances.
Gegenstand der Dissertation ist die Geschichte und Manifestation des Nationaltheaters in Japan, der Transfer einer europäischen Kulturinstitution nach und deren Umsetzungsprozess in Japan, welcher mit der Modernisierung Japans ab Mitte des 19. Jahrhunderts begann und erst hundert Jahre später mit der Eröffnung des ersten Nationaltheaters 1966 endete. Dazu werden theaterhistorische Entwicklungen, Veränderungen in der Theaterproduktion und -architektur in Bezug auf die Genese eines japanischen Nationaltheaters beleuchtet. Das Ergebnis zeigt, dass sich die Institution Nationaltheater in seiner japanischen kulturellen Translation bzw. Manifestation wesentlich von den vom Land selbst als Model anvisierten Pendants in Europa in Inhalt, Organisations- und Produktionsstruktur unterscheidet. Kulturell übersetzt wurde allein die Hülle der europäischen Institution. Das erste Nationaltheater in Japan manifestiert sich als eine von der Regierung im Rahmen des Denkmalschutzgesetztes initiierte und bestimmte, spezifisch japanische Variante eines Nationaltheaters, die unter dem Management von staatlichen Angestellten und Beamten den Erhalt traditioneller Künste in dafür ausgerichteten Bühnen zur Aufgabe hat. Nationaltheaterensemble gibt es nicht, die Produktionen werden mit Schauspielern kommerzieller Theaterunternehmen realisiert. Der lange Prozess dieser Genese liegt in der nicht vorhandenen Theaterförderung seitens der Regierung und der eher zurückhaltenden Haltung der Theaterwelt gegenüber einem staatlich betriebenen Theater begründet. Das Hüllen-Konzept des ersten Nationaltheaters diente, genau wie dessen Management durch Beamte, als Prototyp für die fünf weiteren bis 2004 eröffneten Nationaltheater in Japan, welche als Spartentheater der spezifisch japanischen Vielfalt an Theaterformen, auch in ihrer Bühnenarchitektur Rechnung tragen.
Optimal Control of Partial Integro-Differential Equations and Analysis of the Gaussian Kernel
(2018)
An important field of applied mathematics is the simulation of complex financial, mechanical, chemical, physical or medical processes with mathematical models. In addition to the pure modeling of the processes, the simultaneous optimization of an objective function by changing the model parameters is often the actual goal. Models in fields such as finance, biology or medicine benefit from this optimization step.
While many processes can be modeled using an ordinary differential equation (ODE), partial differential equations (PDEs) are needed to optimize heat conduction and flow characteristics, spreading of tumor cells in tissue as well as option prices. A partial integro-differential equation (PIDE) is a parital differential equation involving an integral operator, e.g., the convolution of the unknown function with a given kernel function. PIDEs occur for example in models that simulate adhesive forces between cells or option prices with jumps.
In each of the two parts of this thesis, a certain PIDE is the main object of interest. In the first part, we study a semilinear PIDE-constrained optimal control problem with the aim to derive necessary optimality conditions. In the second, we analyze a linear PIDE that includes the convolution of the unknown function with the Gaussian kernel.
Wie erleben Schüler*innen die vorhandenen demokratischen Mitgestaltungsmöglichkeiten im Unterricht? Welche Bereitschaft, den Entwicklungsprozess mitzutragen, gibt es in der Schulgemeinschaft? Welche Widerstände gilt es zu beachten und wo liegen bisher ungenutzte Potentiale und Ideen für die Innovation von Schule und Unterricht?
„Wie cool wäre es, wenn wir Schüler einen eigenen TV-Sender hätten?“, schwärmt Sophie. „Vielleicht lieber ein Webchannel, damit man unsere Berichte von überall sehen kann,“ ruft Max. „Auf jeden Fall sollte es um Themen gehen, die uns Schülern wichtig sind“, sind sich die beiden einig. Gemeinsam grübeln sie: Ist das rechtlich überhaupt möglich? Wer kann uns dabei helfen?...
Schule entwickeln – ohne feste Tagesordnung, ohne starres Rednerpodium mit festgelegten Beiträgen und alle Mitglieder der Schulgemeinschaft können frei entscheiden, was sie wann tun möchten und werden mit ihren Ideen und Anliegen gehört. Klingt das sowohl interessant, als auch ein wenig verrückt? Open Space als Werkzeug zur demokratischen Schulentwicklung macht es möglich.
External capital plays an important role in financing entrepreneurial ventures, due to limited internal capital sources. An important external capital provider for entrepreneurial ventures are venture capitalists (VCs). VCs worldwide are often confronted with thousands of proposals of entrepreneurial ventures per year and must choose among all of these companies in which to invest. Not only do VCs finance companies at their early stages, but they also finance entrepreneurial companies in their later stages, when companies have secured their first market success. That is why this dissertation focuses on the decision-making behavior of VCs when investing in later-stage ventures. This dissertation uses both qualitative as well as quantitative research methods in order to provide answer to how the decision-making behavior of VCs that invest in later-stage ventures can be described.
Based on qualitative interviews with 19 investment professionals, the first insight gained is that for different stages of venture development, different decision criteria are applied. This is attributed to different risks and goals of ventures at different stages, as well as the different types of information available. These decision criteria in the context of later-stage ventures contrast with results from studies that focus on early-stage ventures. Later-stage ventures possess meaningful information on financials (revenue growth and profitability), the established business model, and existing external investors that is not available for early-stage ventures and therefore constitute new decision criteria for this specific context.
Following this identification of the most relevant decision criteria for investors in the context of later-stage ventures, a conjoint study with 749 participants was carried out to understand the relative importance of decision criteria. The results showed that investors attribute the highest importance to 1) revenue growth, (2) value-added of products/services for customers, and (3) management team track record, demonstrating differences when compared to decision-making studies in the context of early-stage ventures.
Not only do the characteristics of a venture influence the decision to invest, additional indirect factors, such as individual characteristics or characteristics of the investment firm, can influence individual decisions. Relying on cognitive theory, this study investigated the influence of various individual characteristics on screening decisions and found that both investment experience and entrepreneurial experience have an influence on individual decision-making behavior. This study also examined whether goals, incentive structures, resources, and governance of the investment firm influence decision making in the context of later-stage ventures. This study particularly investigated two distinct types of investment firms, family offices and corporate venture capital funds (CVC), which have unique structures, goals, and incentive systems. Additional quantitative analysis showed that family offices put less focus on high-growth firms and whether reputable investors are present. They tend to focus more on the profitability of a later-stage venture in the initial screening. The analysis showed that CVCs place greater importance on product and business model characteristics than other investors. CVCs also favor later-stage ventures with lower revenue growth rates, indicating a preference for less risky investments. The results provide various insights for theory and practice.
Sample surveys are a widely used and cost effective tool to gain information about a population under consideration. Nowadays, there is an increasing demand not only for information on the population level but also on the level of subpopulations. For some of these subpopulations of interest, however, very small subsample sizes might occur such that the application of traditional estimation methods is not expedient. In order to provide reliable information also for those so called small areas, small area estimation (SAE) methods combine auxiliary information and the sample data via a statistical model.
The present thesis deals, among other aspects, with the development of highly flexible and close to reality small area models. For this purpose, the penalized spline method is adequately modified which allows to determine the model parameters via the solution of an unconstrained optimization problem. Due to this optimization framework, the incorporation of shape constraints into the modeling process is achieved in terms of additional linear inequality constraints on the optimization problem. This results in small area estimators that allow for both the utilization of the penalized spline method as a highly flexible modeling technique and the incorporation of arbitrary shape constraints on the underlying P-spline function.
In order to incorporate multiple covariates, a tensor product approach is employed to extend the penalized spline method to multiple input variables. This leads to high-dimensional optimization problems for which naive solution algorithms yield an unjustifiable complexity in terms of runtime and in terms of memory requirements. By exploiting the underlying tensor nature, the present thesis provides adequate computationally efficient solution algorithms for the considered optimization problems and the related memory efficient, i.e. matrix-free, implementations. The crucial point thereby is the (repetitive) application of a matrix-free conjugated gradient method, whose runtime is drastically reduced by a matrx-free multigrid preconditioner.
Die Vermittlung des Grauens
(2018)
Im Rahmen meiner zweiteiligen Dissertation „Die Vermittlung des Grauens“ untersuchte ich das Einsatzpotential von Multimedia-Technologien an museal aufbereiteten Originalschauplätzen des Opfergedenkens in Frankreich und Deutschland. Vordergründig stand die Klärung der Frage, ob die heute verfügbaren technischen Hilfsmittel die traditionelle Vermittlungsarbeit sinnvoll ergänzen können. Die Forts Douaumont und Vaux in Verdun und die Alte Synagoge Essen schienen mir aufgrund ihrer stark divergierenden Musealisierungen für eine dahingehende Analyse besonders geeignet. Vor Ort widmete ich mich zum einen dem Prozess der „Vergegenwärtigung der Vergangenheit am nahezu originalbelassenen Erinnerungsort durch Multimediaguides“ und begab mich ebenso auf „Spurensuche in der Alten Synagoge Essen“, da die Neukonzeptionierung der Stätte sämtliche Erinnerungen an das örtliche Geschehen im Nationalsozialismus überzeichnet hat. Diese Umstände wirken sich dementsprechend auch unterschiedlich auf die Authentizität des jeweiligen Ortes aus, worauf das dortige Konzept reagieren und für einen angemessenen Ausgleich sorgen muss. Um die Aussagekraft demgemäß zu fördern, bieten sich heutzutage insbesondere Technologien wie Audio- und Multimediaguides an, deren Potential anhand der genannten Objekte überprüft wurde. Neben diese mittlerweile schon traditionellen Maßnahmen, traten im Laufe der Zeit weitere Präsentationsmöglichkeiten wie die Touchscreen-, Virtual oder Augmented Reality-Technologien, der QR-Code, die Nahbereichskommunikation NFC und die sogenannten Museums-Apps, die ebenso zur Sprache kamen. Dieser Umstand trägt sich nicht zuletzt dadurch, dass bei der musealen Vermittlungsarbeit das Zusammenwirken von formalen Bildungsträgern und informellen Lernorten immer mehr an Bedeutung gewinnt. Die große Herausforderung hierbei ist die altersgerechte Darbietung der Inhalte.
This study examines to what extent a banking crisis and the ensuing potential liquidity shortage affect corporate cash holdings. Specifically, how do firms adjust their liquidity management prior to and during a banking crisis when they are restricted in their financing options? These restrictions might not result from firm-specific characteristics but also incorporate the effects of certain regulatory requirements. I analyse the real effects of indicators of a potential crisis and the occurrence of a crisis event on corporate cash holdings for both unregulated and regulated firms from 31 different countries. In contrast to existing studies, I perform this analysis on the basis of a long observation period (1997 to 2014 respectively 2003 to 2014) using multiple crisis indicators (early warning signals) and multiple crisis events. For regulated firms, this study makes use of a unique sample of country-specific regulatory information, which is collected by hand for 15 countries and converted into an ordinal scale based on the severity of the regulation. Regulated firms are selected from a single industry: Real Estate Investment Trusts. These firms invest in real estate properties and let these properties to third parties. Real Estate Investment Trusts that comply with the aforementioned regulations are exempt from income taxation and are punished for a breach, which makes this industry particularly interesting for the analysis of capital structure decisions.
The results for regulated and unregulated firms are mostly inconclusive. I find no convincing evidence that the degree of regulation affects the level of cash holdings for regulated firms before and during a banking crisis. For unregulated firms, I find strong evidence that financially constrained firms have higher cash holdings than unconstrained firms. Further, there is no real evidence that either financially constrained firms or unconstrained firms increase their cash holdings when observing an early warning signal. In case of a banking crisis, the results differ for univariate tests and in panel regressions. In the univariate setting, I find evidence that both types of firms hold higher levels of cash during a banking crisis. In panel regressions, the effect is only evident for financially unconstrained firms from the US, and when controlling for financial stress, it is also apparent for financially constrained US firms. For firms from Europe, the results are predominantly inconclusive. For banking crises that are preceded by an early warning signal, there is only evidence for an increase in cash holdings for unconstrained US firms when controlling for financial stress.
In the present study a non-motion-stabilized scanning Doppler lidar was operated on board of RV Polarstern in the Arctic (June 2014) and Antarctic (December 2015– January 2016). This is the first time that such a system measured on an icebreaker in the Antarctic. A method for a motion correction of the data in the post-processing is presented.
The wind calculation is based on vertical azimuth display (VAD) scans with eight directions that pass a quality control. Additionally a method for an empirical signal-tonoise ratio (SNR) threshold is presented, which can be calculated for individual measurement set-ups. Lidar wind profiles are compared to total of about 120 radiosonde profiles and also to wind measurements of the ship.
The performance of the lidar measurements in comparison with radio soundings generally shows small root mean square deviation (bias) for wind speed of around 1ms-1(0.1ms-1) and for wind direction of around 10 (1). The post-processing of the non-motion-stabilized data shows comparably high quality to studies with motion-stabilized systems.
Two case studies show that a flexible change in SNR threshold can be beneficial for special situations. Further the studies reveal that short-lived low-level jets in the atmospheric boundary layer can be captured by lidar measurements with a high temporal resolution in contrast to routine radio soundings. The present study shows that a non-motionstabilized Doppler lidar can be operated successfully on an
icebreaker. It presents a processing chain including quality control tests and error quantification, which is useful for further measurement campaigns.
Salivary alpha-amylase (sAA) influences the perception of taste and texture, features both relevant in acquiring food liking and, with time, food preference. However, no studies have yet investigated the relationship between basal activity levels of sAA and food preference. We collected saliva from 57 volunteers (63% women) who we assessed in terms of their preference for different food items. These items were grouped into four categories according to their nutritional properties: high in starch, high in sugar, high glycaemic index, and high glycaemic load. Anthropometric markers of cardiovascular risk were also calculated. Our findings suggest that sAA influences food
preference and body composition in women. Regression analysis showed that basal sAA activity is inversely associated with subjective but not self-reported behavioural preference for foods high in sugar. Additionally, sAA and subjective preference are associated with anthropometric markers of cardiovascular risk. We believe that this pilot study points to this enzyme as an interesting candidate to consider among the physiological factors that modulate eating behaviour.
Possibilités et opportunités d’une organisation démocratique du système scolaire luxembourgeois
(2018)
« Aujourd’hui, le socialisme et la démocratie ne sont plus de simples questions réservées aux partis politiques, ce sont des questions vitales. L’école et les enseignants devront s’en saisir (...) et donner au peuple de demain, par un enseignement solide, mais surtout par une éducation formatrice, les moyens de remplir sa mission principale : régner ensemble. » – ein luxemburger Schulfreund, 1920
« Lorsque l’on réfléchit aux perspectives du développement scolaire, notre action doit être guidée par la vision d’une école démocratique, d’une école vivante dans un État démocratique ainsi que par la conception de l’être humain à laquelle elle est associée. Dans ses processus de conception et dans sa vie quotidienne, l’école de demain doit elle-même être une mise en pratique de la démocratie. » (Hartmut Wenzel)
Comment les élèves vivent-ils les possibilités actuelles de participation démocratique dans l’enseignement ? La communauté scolaire est-elle prête à porter le processus de développement ? Quelles résistances faut-il prendre en compte et où se trouvent les potentiels et les idées inexploités pour innover dans l’école et dans l’enseignement ?
« Ce serait vraiment cool si les élèves avaient leur propre chaîne de télévision, non ? », s’extasie Sophie. « Peut-être plutôt une web TV, pour qu’on puisse voir nos reportages de partout dans le monde », s’exclame Max. « En tout cas, il faut que ça parle de sujets qui sont importants pour les élèves » : sur ce point, les deux collégiens sont d’accord. Ensemble, ils se creusent les méninges : pour commencer, est-ce possible juridiquement ? Qui peut nous aider ?
Développer l’école – sans ordre du jour fixe, sans tribune ni interventions programmées. Tous les membres de la communauté scolaire peuvent décider librement ce qu’ils veulent faire et quand ils veulent le faire. Leurs idées et leurs souhaits sont écoutés. Tout cela vous semble à la fois intéressant et un peu fou ? Grâce à la méthode du forum ouvert, outil de développement scolaire démocratique, c’est possible.
Academic achievement is a central outcome in educational research, both in and outside higher education, has direct effects on individual’s professional and financial prospects and a high individual and public return on investment. Theories comprise cognitive as well as non-cognitive influences on achievement. Two examples frequently investigated in empirical research are knowledge (as a cognitive determinant) and stress (as a non-cognitive determinant) of achievement. However, knowledge and stress are not stable, what raises questions as to how temporal dynamics in knowledge on the one hand and stress on the other contribute to achievement. To study these contributions in the present doctoral dissertation, I used meta-analysis, latent profile transition analysis, and latent state-trait analysis. The results support the idea of knowledge acquisition as a cumulative and long-term process that forms the basis for academic achievement and conceptual change as an important mechanism for the acquisition of knowledge in higher education. Moreover, the findings suggest that students’ stress experiences in higher education are subject to stable, trait-like influences, as well as situational and/or interactional, state-like influences which are differentially related to achievement and health. The results imply that investigating the causal networks between knowledge, stress, and academic achievement is a promising strategy for better understanding academic achievement in higher education. For this purpose, future studies should use longitudinal designs, randomized controlled trials, and meta-analytical techniques. Potential practical applications include taking account of students’ prior knowledge in higher education teaching and decreasing stress among higher education students.
Die vorliegende Arbeit befasst sich mit einer komplexen Fragestellung: Wie geschieht der dynamische Umbau der sprachlichen Strukturen unter der Wirkung der innersprachlichen und außersprachlichen Parameter. Im Fokus der Forschung steht der Mechanismus des Werdens der Sprachstruktur, der hier als ein einziger Modus des Daseins der Sprache betrachtet wird. Als Material der Untersuchung dient die Operationalisierung der Bestandteile der verbalen Wortbildungsprozesse in der deutschen Sprache. Die Auswahl des verbalen Teils des Vokabulars ist dadurch bedingt, dass diese Wortart ein Zentralelement ist, das die ganze Sprachmaterie konsolidiert. Als einer der Schlüsselparameter gilt dabei der Frequenzfaktor, der bisher keinen einheitlichen Status in der Sprachtheorie bekommen hat. Die Suche nach dem Ursprung der Macht dieses Faktors führt unumgänglich über die Grenzen des Sprachsystems hinaus. Die Beobachtungen über das Verhalten des Frequenzfaktors in den Prozessen und Strukturen unterschiedlichster Natur lassen behaupten, dass wir es hier mit einem sehr komplexen Phänomen zu tun haben, das ein Bestandteil des allgemeinen kognitiven Anpassungsmechanismus des Menschen zur Umwelt ist. Als solcher ist er auch ein unveräußerlicher Aspekt der Semiose, des Sprachzeichens.
Early life adversity (ELA) poses a high risk for developing major health problems in adulthood including cardiovascular and infectious diseases and mental illness. However, the fact that ELA-associated disorders first become manifest many years after exposure raises questions about the mechanisms underlying their etiology. This thesis focuses on the impact of ELA on startle reflexivity, physiological stress reactivity and immunology in adulthood.
The first experiment investigated the impact of parental divorce on affective processing. A special block design of the affective startle modulation paradigm revealed blunted startle responsiveness during presentation of aversive stimuli in participants with experience of parental divorce. Nurture context potentiated startle in these participants suggesting that visual cues of childhood-related content activates protective behavioral responses. The findings provide evidence for the view that parental divorce leads to altered processing of affective context information in early adulthood.
A second investigation was conducted to examine the link between aging of the immune system and long-term consequences of ELA. In a cohort of healthy young adults, who were institutionalized early in life and subsequently adopted, higher levels of T cell senescence were observed compared to parent-reared controls. Furthermore, the results suggest that ELA increases the risk of cytomegalovirus infection in early childhood, thereby mediating the effect of ELA on T cell-specific immunosenescence.
The third study addresses the effect of ELA on stress reactivity. An extended version of the Cold Pressor Test combined with a cognitive challenging task revealed blunted endocrine response in adults with a history of adoption while cardiovascular stress reactivity was similar to control participants. This pattern of response separation may best be explained by selective enhancement of central feedback-sensitivity to glucocorticoids resulting from ELA, in spite of preserved cardiovascular/autonomic stress reactivity.
Reptiles belong to a taxonomic group characterized by increasing worldwide population declines. However, it has not been until comparatively recent years that public interest in these taxa has increased, and conservation measures are starting to show results. While many factors contribute to these declines, environmental pollution, especially in form of pesticides, has seen a strong increase in the last few decades, and is nowadays considered a main driver for reptile diversity loss. In light of the above, and given that reptiles are extremely underrepresented in ecotoxicological studies regarding the effects of plant protection products, this thesis aims at studying the impacts of pesticide exposure in reptiles, by using the Common wall lizard (Podarcis muralis) as model species. In a first approach, I evaluated the risk of pesticide exposure for reptile species within the European Union, as a means to detect species with above average exposure probabilities and to detect especially sensitive reptile orders. While helpful to detect species at risk, a risk evaluation is only the first step towards addressing this problem. It is thus indispensable to identify effects of pesticide exposure in wildlife. For this, the use of enzymatic biomarkers has become a popular method to study sub-individual responses, and gain information regarding the mode of action of chemicals. However, current methodologies are very invasive. Thus, in a second step, I explored the use of buccal swabs as a minimally invasive method to detect changes in enzymatic biomarker activity in reptiles, as an indicator for pesticide uptake and effects at the sub-individual level. Finally, the last part of this thesis focuses on field data regarding pesticide exposure and its effects on reptile wildlife. Here, a method to determine pesticide residues in food items of the Common wall lizard was established, as a means to generate data for future dietary risk assessments. Subsequently, a field study was conducted with the aim to describe actual effects of pesticide exposure on reptile populations at different levels.
A basic assumption of standard small area models is that the statistic of interest can be modelled through a linear mixed model with common model parameters for all areas in the study. The model can then be used to stabilize estimation. In some applications, however, there may be different subgroups of areas, with specific relationships between the response variable and auxiliary information. In this case, using a distinct model for each subgroup would be more appropriate than employing one model for all observations. If no suitable natural clustering variable exists, finite mixture regression models may represent a solution that „lets the data decide“ how to partition areas into subgroups. In this framework, a set of two or more different models is specified, and the estimation of subgroup-specific model parameters is performed simultaneously to estimating subgroup identity, or the probability of subgroup identity, for each area. Finite mixture models thus offer a fexible approach to accounting for unobserved heterogeneity. Therefore, in this thesis, finite mixtures of small area models are proposed to account for the existence of latent subgroups of areas in small area estimation. More specifically, it is assumed that the statistic of interest is appropriately modelled by a mixture of K linear mixed models. Both mixtures of standard unit-level and standard area-level models are considered as special cases. The estimation of mixing proportions, area-specific probabilities of subgroup identity and the K sets of model parameters via the EM algorithm for mixtures of mixed models is described. Eventually, a finite mixture small area estimator is formulated as a weighted mean of predictions from model 1 to K, with weights given by the area-specific probabilities of subgroup identity.
Die vorliegende Dissertation befasst sich mit der Bildung der Modelle der Komposita in der englischen Sprache.Um eine linguistische Theorie richtig zu bilden, stellen wir 7 Hypothesen auf, die auf umfangreiches englisches Sprachmaterial basieren. Wir schaffen den Regelkreis, der die Möglichkeiten für weitere Untersuchungen in diesem Bereich gibt. In unserem Fall ist diese Untersuchung ein begrenzter Bereich, der als die Bereicherung des Regelkreises von Köhler (2005) gilt (synergetisch-linguistische Modellierung).
Stiftungsunternehmen sind Unternehmen, die sich ganz oder teilweise im Eigentum einer gemeinnützigen oder privaten Stiftung befinden. Die Anzahl an Stiftungsunternehmen in Deutschland ist in den letzten Jahren deutlich gestiegen. Bekannte deutsche Unternehmen wie Aldi, Bosch, Bertelsmann, LIDL oder Würth befinden sich im Eigentum von Stiftungen. Einige von ihnen, wie beispielsweise Fresenius, ZF Friedrichshafen oder Zeiss, sind sogar an der Börse notiert. Die Mehrzahl der Stiftungsunternehmen entsteht dadurch, dass Unternehmensgründer oder Unternehmerfamilien ihr Unternehmen in eine Stiftung einbringen, anstatt es zu vererben oder zu verkaufen.
Die Motive hierfür sind vielfältig und können familiäre Gründe (z. B. Kinderlosigkeit, Vermeidung von Familienstreit), unternehmensbezogene Gründe (z. B. Möglichkeit der langfristigen Planung durch stabile Eigentümerstruktur) und steuerliche Gründe (Vermeidung oder Reduzierung der Erbschaftssteuer) haben oder sind durch die Person des Gründers motiviert (Möglichkeit, das Unternehmen auch nach dem eigenen Tod über die Stiftung noch weiterhin zu prägen). Aufgrund der Tatsache, dass Stiftungsunternehmen zumeist aus Familienunternehmen hervorgehen, wird in der Forschung häufig nicht zwischen Familien- und Stiftungsunternehmen differenziert. Aus diesem Grund werden in dieser Dissertation zu Beginn anhand des Drei-Kreis-Modells für Familienunternehmen die Unterschiede zwischen Stiftungs- und Familienunternehmen dargestellt. Die Ergebnisse zeigen, dass nur eine sehr geringe Anzahl von Stiftungsunternehmen eine große Ähnlichkeit zu klassischen Familienunternehmen aufweist. Die meisten Stiftungsunternehmen unterscheiden sich zum Teil sehr stark von Familienunternehmen. Diese Ergebnisse verdeutlichen, dass Stiftungsunternehmen als separates Forschungsfeld betrachtet werden sollten.
Da innerhalb der Gruppe der Stiftungsunternehmen ebenfalls eine starke Heterogenität herrscht, werden im Anschluss Performanceunterschiede innerhalb der Gruppe der Stiftungsunternehmen untersucht. Hierzu wurden die Daten von 142 deutschen Stiftungsunternehmen für die Jahre 2006-2016 erhoben und mittels einer lineareren Regression ausgewertet. Die Ergebnisse zeigen, dass zwischen den verschiedenen Typen signifikante Unterschiede herrschen. Unternehmen, die von einer gemeinnützigen Stiftung gehalten werden, weisen eine signifikant schlechtere Performance auf, als Unternehmen die eine private Stiftung als Shareholder haben.
Im nächsten Schritt wird die Gruppe der börsennotierten Stiftungsunternehmen untersucht. Mittels einer Ereignisstudie wird getestet, wie sich die Stiftung als Eigentümer eines börsennotierten Unternehmens auf den Shareholder Value auswirkt. Die Ergebnisse zeigen, dass eine Anteilsverringerung einer Stiftung einen positiven Einfluss auf den Shareholder Value hat. Stiftungen werden vom Kapitalmarkt dementsprechend negativ bewertet. Aufgrund der divergierenden Ziele von Stiftung und Unternehmen birgt die Verbindung zwischen Stiftung und Unternehmen potentielle Konflikte und Herausforderungen für die beteiligten Personen. Mittels eines qualitativen explorativen Ansatzes, wird basierend auf Interviews, ein Modell entwickelt, welches die potentiellen Konflikte in Stiftungsunternehmen anhand des Beispiels der Doppelstiftung aufzeigt.
Im letzten Schritt werden Handlungsempfehlungen in Form eines Entwurfs für einen Corporate Governance Kodex erarbeitet, die (potentiellen) Stifterinnen und Stiftern helfen sollen, mögliche Konflikte entweder zu vermeiden oder bereits bestehende Probleme zu lösen.
Die Ergebnisse dieser Dissertation sind relevant für Theorie und Praxis. Aus theoretischer Sicht liegt der Wert dieser Untersuchungen darin, dass Forscher künftig besser zwischen Stiftungs- und Familienunternehmen unterscheiden können. Zudem bringt diese Arbeit den aktuellen Forschungsstand zum Thema Stiftungsunternehmen weiter. Außerdem bietet diese Dissertation insbesondere potentiellen Stiftern einen Überblick über die verschiedenen Ausgestaltungsmöglichkeiten und die Vor- und Nachteile, die diese Konstruktionen mit sich bringen. Die Handlungsempfehlungen ermöglichen es Stiftern, vorab potentielle Gefahren erkennen zu können und diese zu umgehen.
Acute social and physical stress interact to influence social behavior: the role of social anxiety
(2018)
Stress is proven to have detrimental effects on physical and mental health. Due to different tasks and study designs, the direct consequences of acute stress have been found to be wide-reaching: while some studies report prosocial effects, others report increases in antisocial behavior, still others report no effect. To control for specific effects of different stressors and to consider the role of social anxiety in stress-related social behavior, we investigated the effects of social versus physical stress on behavior in male participants possessing different levels of social anxiety. In a randomized, controlled two by two design we investigated the impact of social and physical stress on behavior in healthy young men. We found significant influences on various subjective increases in stress by physical and social stress, but no interaction effect. Cortisol was significantly increased by physical stress, and the heart rate was modulated by physical and social stress as well as their combination. Social anxiety modulated the subjective stress response but not the cortisol or heart rate response. With respect to behavior, our results show that social and physical stress interacted to modulate trust, trustworthiness, and sharing. While social stress and physical stress alone reduced prosocial behavior, a combination of the two stressor modalities could restore prosociality. Social stress alone reduced nonsocial risk behavior regardless of physical stress. Social anxiety was associated with higher subjective stress responses and higher levels of trust. As a consequence, future studies will need to investigate further various stressors and clarify their effects on social behavior in health and social anxiety disorders.
The changing views on the evolutionary relationships of extant Salamandridae (Amphibia: Urodela)
(2018)
The phylogenetic relationships among members of the family Salamandridae have been repeatedly investigated over the last 90 years, with changing character and taxon sampling. We review the changing composition and the phylogenetic position of salamandrid genera and species groups and add a new phylogeny based exclusively on sequences of nuclear genes. Salamandrina often changed its position depending on the characters used. It was included several times in a clade together with the primitive newts (Echinotriton, Pleurodeles, Tylototriton) due to their seemingly ancestral morphology. The latter were often inferred as a monophyletic clade. Respective monophyly was almost consistently established in all molecular studies for true salamanders (Chioglossa, Lyciasalamandra, Mertensiella, Salamandra), modern Asian newts (Cynops, Laotriton, Pachytriton, Paramesotriton) and modern New World newts (Notophthalmus, Taricha). Reciprocal non-monophyly has been established through molecular studies for the European mountain newts (Calotriton, Euproctus) and the modern European newts (Ichthyosaura, Lissotriton, Neurergus, Ommatotriton, Triturus) since Calotriton was identified as the sister lineage of Triturus. In pre-molecular studies, their respective monophyly had almost always been assumed, mainly because a complex courtship behaviour shared by their respective members. Our nuclear tree is nearly identical to a mito-genomic tree, with all but one node being highly supported. The major difference concerns the position of Calotriton, which is no longer nested within the modern European newts. This has implications for the evolution of courtship behaviour of European newts. Within modern European newts, Ichthyosaura and Lissotriton changed their position compared to the mito-genomic tree. Previous molecular trees based on seemingly large nuclear data sets, but analysed together with mitochondrial data, did not reveal monophyly of modern European newts since taxon sampling and nuclear gene coverage was too poor to obtain conclusive results. We therefore conclude that mitochondrial and nuclear data should be analysed on their own.
Species can show strong variation of local abundance across their ranges. Recent analyses suggested that variation in abundance can be related to environmental suitability, as the highest abundances are often observed in populations living in the most suitable areas. However, there is limited information on the mechanisms through which variation in environmental suitability determines abundance. We analysed populations of the microendemic salamander Hydromantes flavus, and tested several hypotheses on potential relationships linking environmental suitability to population parameters. For multiple populations across the whole species range, we assessed suitability using species distribution models, and measured density, activity level, food intake and body condition index. In high-suitability sites, the density of salamanders was up to 30-times higher than in the least suitable ones. Variation in activity levels and population performance can explain such variation of abundance. In high-suitability sites, salamanders were active close to the surface, and showed a low frequency of empty stomachs. Furthermore, when taking into account seasonal variation, body condition was better in the most suitable sites. Our results show that the strong relationship between environmental suitability and population abundance can be mediated by the variation of parameters strongly linked to individual performance and fitness.
Das Ideal einer lebendigen Demokratie mit engagierten Bürger/innen lässt nach Wegen suchen, um die Partizipationsbereitschaft nachkommender Generationen zu fördern. Ausgehend von der Prämisse, dass das Wohlbefinden einen zentralen Motivator darstellt, der sich auch bei jungen Menschen mithilfe der Konzepte der Positiven Psychologie gezielt fördern lässt (Brohm & Endres, 2015), nähert sich der vorliegende Beitrag den beiden folgenden Forschungsfragen: Erstens, lässt sich ein Zusammenhang zwischen dem Wohlbefinden Jugendlicher und ihrer politischen Partizipationsbereitschaft respektive ihrem politischen Interesse empirisch nachweisen? Zweitens, in welchen Kontexten und in welchem Maße erleben Jugendliche Wohlbefinden in der Auseinandersetzung mit politischen Themen, Akteur/innen und Prozessen?
Da bisherige bundesweite und regionale Studien zu den Themen Jugend, Politik und politisch-gesellschaftlicher Teilhabe nur in bedingtem Maße Rückschlüsse auf die fünf Elemente des Wohlbefindens nach Seligman (2012) zuließen, wurde im Vorfeld des vorliegenden Beitrags eine schriftliche Befragung von 100 Jugendlichen aus dem saarländischen Landkreis Saarlouis durchgeführt.
Die Befragten charakterisieren sich mehrheitlich als allgemein aufgeschlossen und interessiert, doch es gelingt der Politik und ihren Mittler/innen nur eingeschränkt, dieses Potenzial in aktive politische Teilhabe zu übersetzen. Unter anderem persönliche Kontakte zu politisch Engagierten und eigene Erfahrungen in politischen Verbänden erweisen sich indes als positiv und korrelieren mit dem politischen Interesse und der Offenheit der Jugendlichen gegenüber politischer Partizipation.
Das Working Paper beleuchtet den Themenbereich‚ Mobilität und Verkehr und arbeitet Herausforderungen für die Raumentwicklung der Großregion ab. Insbesondere legt es einen Fokus auf die Territoriale Verteilung der grenzüberschreitenden Arbeitnehmerströme und deren Abhängigkeit vom Auto innerhalb der Großregion sowie den Einfluss von EU Politik auf Herausforderungen des grenzüberschreitenden Verkehrs.
Surveys are commonly tailored to produce estimates of aggregate statistics with a desired level of precision. This may lead to very small sample sizes for subpopulations of interest, defined geographically or by content, which are not incorporated into the survey design. We refer to subpopulations where the sample size is too small to provide direct estimates with adequate precision as small areas or small domains. Despite the small sample sizes, reliable small area estimates are needed for economic and political decision making. Hence, model-based estimation techniques are used which increase the effective sample size by borrowing strength from other areas to provide accurate information for small areas. The paragraph above introduced small area estimation as a field of survey statistics where two conflicting philosophies of statistical inference meet: the design-based and the model-based approach. While the first approach is well suited for the precise estimation of aggregate statistics, the latter approach furnishes reliable small area estimates. In most applications, estimates for both large and small domains based on the same sample are needed. This poses a challenge to the survey planner, as the sampling design has to reflect different and potentially conflicting requirements simultaneously. In order to enable efficient design-based estimates for large domains, the sampling design should incorporate information related to the variables of interest. This may be achieved using stratification or sampling with unequal probabilities. Many model-based small area techniques require an ignorable sampling design such that after conditioning on the covariates the variable of interest does not contain further information about the sample membership. If this condition is not fulfilled, biased model-based estimates may result, as the model which holds for the sample is different from the one valid for the population. Hence, an optimisation of the sampling design without investigating the implications for model-based approaches will not be sufficient. Analogously, disregarding the design altogether and focussing only on the model is prone to failure as well. Instead, a profound knowledge of the interplay between the sample design and statistical modelling is a prerequisite for implementing an effective small area estimation strategy. In this work, we concentrate on two approaches to address this conflict. Our first approach takes the sampling design as given and can be used after the sample has been collected. It amounts to incorporate the survey design into the small area model to avoid biases stemming from informative sampling. Thus, once a model is validated for the sample, we know that it holds for the population as well. We derive such a procedure under a lognormal mixed model, which is a popular choice when the support of the dependent variable is limited to positive values. Besides, we propose a three pillar strategy to select the additional variable accounting for the design, based on a graphical examination of the relationship, a comparison of the predictive accuracy of the choices and a check regarding the normality assumptions.rnrnOur second approach to deal with the conflict is based on the notion that the design should allow applying a wide variety of analyses using the sample data. Thus, if the use of model-based estimation strategies can be anticipated before the sample is drawn, this should be reflected in the design. The same applies for the estimation of national statistics using design-based approaches. Therefore, we propose to construct the design such that the sampling mechanism is non-informative but allows for precise design-based estimates at an aggregate level.
Die Untersuchung verbindet Methoden der Korpuslinguistik und des close readings, um an einem repräsentativen Einzeltext mittlerer Länge das Verhältnis der syntaktischen und metrischen Ebene im mittelhochdeutschen Reimpaarvers zu untersuchen. Herausgearbeitet werden regelmäßig wiederkehrende Muster, die beide Ebenen stets gleich aufeinander abbilden. Diese Regelmäßigkeiten lassen sich aus den Lautstrukturen des mhd. Wortschatzes, den syntaktischen Bauplänen der Phrasen und Sätze, schließlich den Erfordernissen des metrischen Schemas erklären. Der häufig zur Erklärung herangezogene Reimzwang erweist sich bei näherer Betrachtung als eher sekundärer Einfluss auf die syntaktische Struktur. Neben typischen „Normalfällen“ bei denen sich statistisch häufige Betonungsmuster der Wörter, in üblichen, einfachen Satzstellungsmustern in immer gleicher Weise problemlos in den Reimpaarvers integrieren lassen, können auch wiederkehrende Abweichungsvarianten erklärt und beschrieben werden. Die festgestellten Regularitäten sind nur zu einem kleinen Teil und in wenigen Fällen deterministisch, es lässt sich jedoch, um die statistischen Auffälligkeiten zu begründen, zeigen, welche Vorteile sich aus bestimmten Varianten ergeben und welche Schwierigkeiten bei anderen entstehen, wie sich eine Variante durch eine andere ersetzen lässt. Beschrieben wird so der Gestaltungsraum des Dichters und die von ihm gewählten Lösungen. Indirekt ergibt sich zugleich ein Negativbild der Syntax, die den Zwängen des metrischen Schemas nicht unterworfen ist.
Given a compact set K in R^d, the theory of extension operators examines the question, under which conditions on K, the linear and continuous restriction operators r_n:E^n(R^d)→E^n(K),f↦(∂^α f|_K)_{|α|≤n}, n in N_0 and r:E(R^d)→E(K),f↦(∂^α f|_K)_{α in N_0^d}, have a linear and continuous right inverse. This inverse is called extension operator and this problem is known as Whitney's extension problem, named after Hassler Whitney. In this context, E^n(K) respectively E(K) denote spaces of Whitney jets of order n respectively of infinite order. With E^n(R^d) and E(R^d), we denote the spaces of n-times respectively infinitely often continuously partially differentiable functions on R^d. Whitney already solved the question for finite order completely. He showed that it is always possible to construct a linear and continuous right inverse E_n for r_n. This work is concerned with the question of how the existence of a linear and continuous right inverse of r, fulfilling certain continuity estimates, can be characterized by properties of K. On E(K), we introduce a full real scale of generalized Whitney seminorms (|·|_{s,K})_{s≥0}, where |·|_{s,K} coincides with the classical Whitney seminorms for s in N_0. We equip also E(R^d) with a family (|·|_{s,L})_{s≥0} of those seminorms, where L shall be a a compact set with K in L-°. This family of seminorms on E(R^d) suffices to characterize the continuity properties of an extension operator E, since we can without loss of generality assume that E(E(K)) in D^s(L).
In Chapter 2, we introduce basic concepts and summarize the classical results of Whitney and Stein.
In Chapter 3, we modify the classical construction of Whitney's operators E_n and show that |E_n(·)|_{s,L}≤C|·|_{s,K} for s in[n,n+1).
In Chapter 4, we generalize a result of Frerick, Jordá and Wengenroth and show that LMI(1) for K implies the existence of an extension operator E without loss of derivatives, i.e. we have it fulfils |E(·)|_{s,L}≤C|·|_{s,K} for all s≥0. We show that a large class of self similar sets, which includes the Cantor set and the Sierpinski triangle, admits an extensions operator without loss of derivatives.
In Chapter 5 we generalize a result of Frerick, Jordá and Wengenroth and show that WLMI(r) for r≥1 implies the existence of a tame linear extension operator E having a homogeneous loss of derivatives, such that |E(·)|_{s,L}≤C|·|_{(r+ε)s,K} for all s≥0 and all ε>0.
In the last chapter we characterize the existence of an extension operator having an arbitrary loss of derivatives by the existence of measures on K.
The main socio-ecological pressures in five wetlands in the Greater Accra Region were first identified and then summarized by reviewing the relevant literature. As a second step, fieldwork in the region was carried out in 2016 to further examine the pressures identified in the literature. Most research on the wetlands in Ghana was published around the year 2000. Yet, similar socio-ecological pressures persist today. Based on both, fieldwork observations and the literature review, these pressures were ranked using the IUCN pressures system analysis framework. It is suggested that further research needs to proceed with uncovering how trade-offs between ecosystem and quality of life can be defined.
Der vorliegende Artikel beschreibt die klimatische Situation des Naturparks Saar-Hunsrück. Neben der Einordnung der Region in die großskalige klimatische Zirkulation werden die wesentlichen Klimaelemente beschrieben. Da sich die Klimaelemente mit zunehmender Höhe verändern, bestimmt im unteren Saartal, im Saar-Nahe-Bergland und Hunsrück mit Osburger Hochwald, Schwarzwälder Hochwald und Idarwald die Höhenlage entscheidend die räumliche Struktur der einzelnen Klimaelemente. Die Niederschlagsverteilung zeigt deutlich den Luveffekt in den westlichen Teilen des Naturparks und die Abnahme der Niederschlagshöhen in nordöstlicher Richtung. Die räumlichen Muster der mittleren und maximalen Lufttemperatur folgen der Topographie, während Minimalwerte der Temperatur ein weniger differenziertes Bild zeigen. In den tiefer gelegenen Regionen des Naturparks treten 4-7 Hitzetage in langjährigen Mittel auf, in den Hochlagen des Hunsrücks werden nur noch 1-3 Tage / Jahr beobachtet. Oberhalb der 600 m-Höhenlinie ergeben sich im Mittel 110-130 Frosttage im Jahr, im südwestlichen Teil des Naturparks geht die Zahl auf 50 Tage / Jahr zurück. Die mittlere Anzahl der Tage mit Schneedecke liegt, bezogen auf das Areal des Naturparks, insgesamt zwischen 10 und 90 Tagen pro Jahr. Ihre Veränderung infolge des regionalen Klimawandels zeigt eine Abnahme zwischen 3-15 Tagen pro Jahr zwischen den Zeiträumen 1961-1990 und 1981-2010. Die aktuelle Sonnenscheindauer beträgt im westlichen Teil des Naturparks im Mittel 1500-1600 Sonnenscheinstunden pro Jahr, im südöstlichen Teil werden bis 1600 Stunden pro Jahr erreicht.
Kartenschätze aus Italien
(2018)
Die Entdeckungen der Neuzeit sowie verbesserte Druckverfahren führten ab dem 16. Jahrhundert zu einem enormen Aufschwung der Kartographie. Gerade in Italien entstanden blühende kartographische Zentren mit exzellentem Ruf, die innerhalb kurzer Zeit große Fortschritte hinsichtlich Genauigkeit und Übersichtlichkeit machten. Aus dem der Universitätsbibliothek Trier vermachten Nachlass des Kartensammlers Fritz Hellwig werden drei repräsentative Beispiele vorgestellt.
Die A4-Strategie versucht, eine Antwort auf die Frage zu geben, ob es in der modernen Medienlandschaft optimale und effiziente Kommunikationsstrategien gibt, deren Erfolg nicht von der Höhe des Budgets abhängig ist und die gleichzeitig eine hohe Kundenbindung bewirken und eine effiziente Auswahl der Kommunikationsinstrumente sichert. Dies ist gerade für KMUs von besonderer Bedeutung, die sich in einem komplexen und globalisierten Marktumfeld bewegen. Die Marketingkommunikation ist nicht nur ein unvermeidliches Werkzeug, um die Verkaufszahlen zu steigern. Sie bedarf heutzutage auch einer durchdachten Strategie. Denn es wird erst eine erfolgreiche Interaktion zwischen diesen Partnern (Unternehmen und Kunden) stattfinden, wenn sowohl ein optimaler Unternehmenswert als auch ein Kundenwert generiert wird. Die A4-Strategie hilft zugleich dabei, Antworten auf die für eine optimale Marketingkommunikation relevante Fragen zu finden: Wer kann einkaufen? Wer kauft tatsächlich ein? Was sind die relevanten Informationen über den, der tatsächlich einkauft? Anhand der Antworten auf diese Frage wird ermittelt, wo und wie die potentielle Kundschaft besser akquiriert und wo und wie die bestehende Kundschaft optimal betreut werden kann. Dieses Konzept bietet eine strukturierte Herangehensweise und Vorgehensweise, um eine Kommunikationsstrategie je nach Situation zu entwickeln. Sie ist somit keine fertige Lösung, sondern schafft sie Rahmen für ein methodisches Entscheidungsprozess. Sie hilft zudem situationsadäquat Entscheidungen zu treffen und Handlungen vorzunehmen, die diese Entscheidungen konsequent umzusetzen.
Early life adversity (ELA) is associated with a higher risk for diseases in adulthood. Changes in the immune system have been proposed to underlie this association. Although higher levels of inflammation and immunosenescence have been reported, data on cell-specific immune effects are largely absent. In addition, stress systems and health behaviors are altered in ELA, which may contribute to the generation of the "ELA immune phenotype". In this thesis, we have investigated the ELA immune phenotype on a cellular level and whether this is an indirect consequence of changes in behavior or stress reactivity. To address these questions the EpiPath cohort was established, consisting of 115 young adults with or without ELA. ELA participants had experienced separation from their parents in early childhood and were subsequently adopted, which is a standard model for ELA, whereas control participants grew up with their biological parents. At a first visit, blood samples were taken for analysis of epigenetic markers and immune parameters. A selection of the cohort underwent a standardized laboratory stress test (SLST). Endocrine, immune, and cardiovascular parameters were assessed at several time points before and after stress. At a second visit, participants underwent structural clinical interviews and filled out psychological questionnaires. We observed a higher number of activated T cells in ELA, measured by HLA-DR and CD25 expression. Neither cortisol levels nor health-risk behaviors explained the observed group differences. Besides a trend towards higher numbers of CCR4+CXCR3-CCR6+ CD4 T cells in ELA, relative numbers of immune cell subsets in circulation were similar between groups. No difference was observed in telomere length or in methylation levels of age-related CpGs in whole blood. However, we found a higher expression of senescence markers (CD57) on T cells in ELA. In addition, these cells had an increased cytolytic potential. A mediation analysis demonstrated that cytomegalovirus infection " an important driving force of immunosenescence " largely accounted for elevated CD57 expression. The psychological investigations revealed that after adoption, family conditions appeared to have been similar to the controls. However, PhD thesis MMC Elwenspoek 18 ELA participants scored higher on a depression index, chronic stress, and lower on self-esteem. Psychological, endocrine, and cardiovascular parameters significantly responded to the SLST, but were largely similar between the two groups. Only in a smaller subset of groups matched for gender, BMI, and age, the cortisol response seemed to be blunted in ELA participants. Although we found small differences in the methylation level of the GR promoter, GR sensitivity and mRNA expression levels GR as well as expression of the GR target genes FKBP5 and GILZ were similar between groups. Taken together, our data suggest an elevated state of immune activation in ELA, in which particularly T cells are affected. Furthermore, we found higher levels of T cells immunosenescence in ELA. Our data suggest that ELA may increase the risk of cytomegalovirus infection in early childhood, thereby mediating the effect of ELA on T cell specific immunosenescence. Importantly, we found no evidence of HPA dysregulation in participants exposed to ELA in the EpiPath cohort. Thus, the observed immune phenotype does not seem to be secondary to alterations in the stress system or health-risk behaviors, but rather a primary effect of early life programming on immune cells. Longitudinal studies will be necessary to further dissect cause from effect in the development of the ELA immune phenotype.
There are large health, societal, and economic costs associated with attrition from psychological services. The recently emerged, innovative statistical tool of complex network analysis was used in the present proof-of-concept study to improve the prediction of attrition. Fifty-eight patients undergoing psychological treatment for mood or anxiety disorders were assessed using Ecological Momentary Assessments four times a day for two weeks before treatment (3,248 measurements). Multilevel vector autoregressive models were employed to compute dynamic symptom networks. Intake variables and network parameters (centrality measures) were used as predictors for dropout using machine-learning algorithms. Networks for patients differed significantly between completers and dropouts. Among intake variables, initial impairment and sex predicted dropout explaining 6% of the variance. The network analysis identified four additional predictors: Expected force of being excited, outstrength of experiencing social support, betweenness of feeling nervous, and instrength of being active. The final model with the two intake and four network variables explained 32% of variance in dropout and identified 47 out of 58 patients correctly. The findings indicate that patients" dynamic network structures may improve the prediction of dropout. When implemented in routine care, such prediction models could identify patients at risk for attrition and inform personalized treatment recommendations.
Das Working Paper beleuchtet den Themenbereich Energie und arbeitet Herausforderungen für die Raumentwicklung der Großregion ab. Es diskutiert den Begriff der Energiewende und legt einen Fokus auf Energiesysteme und –träger, insbesondere den Ausbau der Windkraft und Energiegewinnung aus Biomasse im Zusammenhang mit der Entwicklung fossil-atomarer Energiequellen in Deutschland und Frankreich.
Die räumliche Entwicklung von Städten und Regionen wird durch Trends wie Klimawandel, demographische Veränderungen und Strukturwandel beeinflusst, welche nicht an Verwaltungsgrenzen aufhören, sondern die Entwicklung großflächiger Gebiete bestimmen. Außerdem weisen Grenzräume häufig funktionale und thematische Verflechtungen auf, die über die nationalen Grenzen hinweg bestehen. Damit verbunden sind ein regelmäßiger Austausch und Abhängigkeiten zwischen Grenzräumen und deren Bewohnern. Daher ist die Koordination der grenzüberschreitenden Raumentwicklung entscheidend für eine zukunftsorientierte und nachhaltige räumliche Entwicklung. Aufgrund seiner hohen Bedeutung wird dieses Thema von europäischen Wissenschaftlern in der ersten Ausgabe der Themenhefte Borders in Perspective aus verschiedenen Perspektiven beleuchtet.
This thesis considers the general task of computing a partition of a set of given objects such that each set of the partition has a cardinality of at least a fixed number k. Among such kinds of partitions, which we call k-clusters, the objective is to find the k-cluster which minimises a certain cost derived from a given pairwise difference between objects which end up the same set. As a first step, this thesis introduces a general problem, denoted by (||.||,f)-k-cluster, which models the task to find a k-cluster of minimum cost given by an objective function computed with respect to specific choices for the cost functions f and ||.||. In particular this thesis considers three different choices for f and also three different choices for ||.|| which results in a total of nine different variants of the general problem. Especially with the idea to use the concept of parameterised approximation, we first investigate the role of the lower bound on the cluster cardinalities and find that k is not a suitable parameter, due to remaining NP-hardness even for the restriction to the constant 3. The reductions presented to show this hardness yield the even stronger result which states that polynomial time approximations with some constant performance ratio for any of the nine variants of (||.||,f)-k-cluster require a restriction to instances for which the pairwise distance on the objects satisfies the triangle inequality. For this restriction to what we informally refer to as metric instances, constant-factor approximation algorithms for eight of the nine variants of (||.||,f)-k-cluster are presented. While two of these algorithms yield the provably best approximation ratio (assuming P!=NP), others can only guarantee a performance which depends on the lower bound k. With the positive effect of the triangle inequality and applications to facility location in mind, we discuss the further restriction to the setting where the given objects are points in the Euclidean metric space. Considering the effect of computational hardness caused by high dimensionality of the input for other related problems (curse of dimensionality) we check if this is also the source of intractability for (||.||,f)-k-cluster. Remaining NP-hardness for restriction to small constant dimensionality however disproves this theory. We then use parameterisation to develop approximation algorithms for (||.||,f)-k-cluster without restriction to metric instances. In particular, we discuss structural parameters which reflect how much the given input differs from a metric. This idea results in parameterised approximation algorithms with parameters such as the number of conflicts (our name for pairs of objects for which the triangle inequality is violated) or the number of conflict vertices (objects involved in a conflict). The performance ratios of these parameterised approximations are in most cases identical to those of the approximations for metric instances. This shows that for most variants of (||.||,f)-k-cluster efficient and reasonable solutions are also possible for non-metric instances.
Die Dissertation untersucht vergleichend deutsch-japanische fotografische Kriegspropaganda des Zweiten Weltkrieges anhand der zu jener Zeit auflagenstärksten illustrierten Zeitschriften "Illustrierter Beobachter" auf deutscher und "Shashin Shūhō" (Fotografische Wochenzeitung) auf japanischer Seite. Unter Rückgriff auf die ikonographisch-ikonologische Methode des Kunsthistorikers Erwin Panofsky bei gleichzeitiger Bezugnahme auf das Bildverständnis Charles Sanders Peirces werden Muster der bildlichen Darstellung von Kindern und Jugendlichen analysiert, um hierdurch Rückschlüsse zu ziehen auf Gemeinsamkeiten und Unterschiede in der Ausgestaltung der Bildpropaganda beider Länder unmittelbar vor und im Zweiten Weltkrieg (1939-1945), auf allgemeine Tendenzen in der Gestaltung von Propaganda im selben Zeitraum, auf die Organisation und Funktion von Propaganda in radikalnationalistischen Staaten. Gleichzeitig wird durch Einbeziehung der Rezipientensicht die Frage nach Mehrdeutigkeit und, hiermit einhergehend, Wirkungsweise und Wirkungsgrad der Propaganda gestellt. Schwerpunkt der Untersuchung bilden sämtliche publizierten Ausgaben der zweiten Jahreshälften 1938 und 1943.
Das Working Paper beleuchtet den Themenbereich Beschäftigung und wirtschaftliche Entwicklung und arbeitet Herausforderungen für die Raumentwicklung der Großregion ab. Insbesondere legt es einen Fokus auf die Industriegeschichte sowie die Beschäftigung und grenzüberschreitende Arbeit in der Großregion.
Das Working Paper beleuchtet den Themenbereich‚Demografie und Migration und arbeitet Herausforderungen für die Raumentwicklung der Großregion ab. Insbesondere legt es einen Fokus auf die grenzüberschreitende Wohnmobilität an den Grenzen des Großherzogtums; die Bevölkerungsalterung und die Sicherung der Daseinsvorsorge im Gesundheitsbereich in ländlichen Gebieten.
At any given moment, our senses are assaulted with a flood of information from the environment around us. We need to pick our way through all this information in order to be able to effectively respond to that what is relevant to us. In most cases we are usually able to select information relevant to our intentions from what is not relevant. However, what happens to the information that is not relevant to us? Is this irrelevant information completely ignored so that it does not affect our actions? The literature suggests that even though we mayrnignore an irrelevant stimulus, it may still interfere with our actions. One of the ways in which irrelevant stimuli can affect actions is by retrieving a response with which it was associated. An irrelevant stimulus that is presented in close temporal contiguity with a relevant stimulus can be associated with the response made to the relevant stimulus " an observation termed distractor-response binding (Rothermund, Wentura, & De Houwer, 2005). The studies presented in this work take a closer look at such distractor-response bindings, and therncircumstances in which they occur. Specifically, the study reported in chapter 6 examined whether only an exact repetition of the distractor can retrieve the response with which it was associated, or whether even similar distractors may cause retrieval. The results suggested that even repeating a similar distractor caused retrieval, albeit less than an exact repetition. In chapter 7, the existence of bindings between a distractor and a response were tested beyond arnperceptual level, to see whether they exist at an (abstract) conceptual level. Similar to perceptual repetition, distractor-based retrieval of the response was observed for the repetition of concepts. The study reported in chapter 8 of this work examined the influence of attention on the feature-response binding of irrelevant features. The results pointed towards a stronger binding effects when attention was directed towards the irrelevant feature compared to whenrnit was not. The study in chapter 9 presented here looked at the processes underlying distractor-based retrieval and distractor inhibition. The data suggest that motor processes underlie distractor-based retrieval and cognitive process underlie distractor inhibition. Finally, the findings of all four studies are also discussed in the context of learning.
We will consider discrete dynamical systems (X,T) which consist of a state space X and a linear operator T acting on X. Given a state x in X at time zero, its state at time n is determined by the n-th iteration T^n(x). We are interested in the long-term behaviour of this system, that means we want to know how the sequence (T^n (x))_(n in N) behaves for increasing n and x in X. In the first chapter, we will sum up the relevant definitions and results of linear dynamics. In particular, in topological dynamics the notions of hypercyclic, frequently hypercyclic and mixing operators will be presented. In the setting of measurable dynamics, the most important definitions will be those of weakly and strongly mixing operators. If U is an open set in the (extended) complex plane containing 0, we can define the Taylor shift operator on the space H(U) of functions f holomorphic in U as Tf(z) = (f(z)- f(0))/z if z is not equal to 0 and otherwise Tf(0) = f'(0). In the second chapter, we will start examining the Taylor shift on H(U) endowed with the topology of locally uniform convergence. Depending on the choice of U, we will study whether or not the Taylor shift is weakly or strongly mixing in the Gaussian sense. Next, we will consider Banach spaces of functions holomorphic on the unit disc D. The first section of this chapter will sum up the basic properties of Bergman and Hardy spaces in order to analyse the dynamical behaviour of the Taylor shift on these Banach spaces in the next part. In the third section, we study the space of Cauchy transforms of complex Borel measures on the unit circle first endowed with the quotient norm of the total variation and then with a weak-* topology. While the Taylor shift is not even hypercyclic in the first case, we show that it is mixing for the latter case. In Chapter 4, we will first introduce Bergman spaces A^p(U) for general open sets and provide approximation results which will be needed in the next chapter where we examine the Taylor shift on these spaces on its dynamical properties. In particular, for 1<=p<2 we will find sufficient conditions for the Taylor shift to be weakly mixing or strongly mixing in the Gaussian sense. For p>=2, we consider specific Cauchy transforms in order to determine open sets U such that the Taylor shift is mixing on A^p(U). In both sections, we will illustrate the results with appropriate examples. Finally, we apply our results to universal Taylor series. The results of Chapter 5 about the Taylor shift allow us to consider the behaviour of the partial sums of the Taylor expansion of functions in general Bergman spaces outside its disc of convergence.
The forward effect of testing refers to the finding that retrieval practice of previously studied information increases retention of subsequently studied other information. It has recently been hypothesized that the forward effect (partly) reflects the result of a reset-of-encoding (ROE) process. The proposal is that encoding efficacy decreases with an increase in study material, but testing of previously studied information resets the encoding process and makes the encoding of the subsequently studied information as effective as the encoding of the previously studied information. The goal of the present study was to verify the ROE hypothesis on an item level basis. An experiment is reported that examined the effects of testing in comparison to restudy on items’ serial position curves. Participants studied three lists of items in each condition. In the testing condition, participants were tested immediately on non-target lists 1 and 2, whereas in the restudy condition, they restudied lists 1 and 2. In both conditions, participants were tested immediately on target list 3. Influences of condition and items’ serial learning position on list 3 recall were analyzed. The results showed the forward effect of testing and furthermore that this effect varies with items’ serial list position. Early target list items at list primacy positions showed a larger enhancement effect than middle and late target list items at non-primacy positions. The results are consistent with the ROE hypothesis on an item level basis. The generalizability of the ROE hypothesis across different experimental tasks, like the list-method directed-forgetting task, is discussed.
The implicit power motive is one of the most researched motives in motivational psychology—at least in adults. Children have rarely been subject to investigation and there are virtually no results on behavioral and affective correlates of the implicit power motive in children. As behavior and affect are important components of conceptual validation, the empirical data in this dissertation focused on identifying three correlates, namely resource control behavior (study 1), power stress (study 2), and persuasive behavior (study 3). In each study, the implicit power motive was measured via the Picture Story Exercise, using an adapted version for children. Children across samples were between 4 and 11 years old.
Results from study 1 and 2 showed that children’s power-related behavior corresponded with evidence from adult samples: children with a high implicit power motive secure attractive resources and show negative reactions to a thwarted attempt to exert influence. Study 3 contradicted existing evidence with adults in that children’s persuasive behavior was not associated with nonverbal, but with verbal strategies of persuasion. Despite this inconsistency, these results are, together with the validation of a child-friendly Picture Story Exercise version, an important step into further investigating and confirming the concept of the implicit power motive and how to measure it in children.
Fostering positive and realistic self-concepts of individuals is a major goal in education worldwide (Trautwein & Möller, 2016). Individuals spend most of their childhood and adolescence in school. Thus, schools are important contexts for individuals to develop positive self-perceptions such as self-concepts. In order to enhance positive self-concepts in educational settings and in general, it is indispensable to have a comprehensive knowledge about the development and structure of self-concepts and their determinants. To date, extensive empirical and theoretical work on antecedents and change processes of self-concept has been conducted. However, several research gaps still exist, and several of these are the focus of the present dissertation. Specifically, these research gaps encompass (a) the development of multiple self-concepts from multiple perspectives regarding stability and change, (b) the direction of longitudinal interplay between self-concept facets over the entire time period from childhood to late adolescence, and (c) the evidence that a recently developed structural model of academic self-concept (nested Marsh/Shavelson model [Brunner et al., 2010]) fits the data in elementary school students, (d) the investigation of structural changes in academic self-concept profile formation within this model, (e) the investigation of dimensional comparison processes as determinants of academic self-concept profile formation in elementary school students within the internal/external frame of reference model (I/E model; Marsh, 1986), (f) the test of moderating variables for dimensional comparison processes in elementary school, (g) the test of the key assumptions of the I/E model that effects of dimensional comparisons depend to a large degree on the existence of achievement differences between subjects, and (h) the generalizability of the findings regarding the I/E model over different statistical analytic methods. Thus, the aim of the present dissertation is to contribute to close these gaps with three studies. Thereby, data from German students enrolled in elementary school to secondary school education were gathered in three projects comprising the developmental time span from childhood to adolescence (ages 6 to 20). Three vital self-concept areas in childhood and adolescence were in-vestigated: general self-concept (i.e., self-esteem), academic self-concepts (general, math, reading, writing, native language), and social self-concepts (of acceptance and assertion). In all studies, data were analyzed within a latent variable framework. Findings are discussed with respect to the research aims of acquiring more comprehensive knowledge on the structure and development of significant self-concept in childhood and adolescence and their determinants. In addition, theoretical and practical implications derived from the findings of the present studies are outlined. Strengths and limitations of the present dissertation are discussed. Finally, an outlook for future research on self-concepts is given.
“Sozialismus und Demokratie sind heute nicht mehr bloße Parteifragen, es sind Lebensfragen. Schule und Lehrer kommen an ihnen nicht vorbei (…), durch gediegenen Unterricht, vor allem aber durch charakterbildende Erziehung das Volk von morgen zu seiner großen Aufgabe des Mitherrschens zu befähigen.” – ein luxemburger Schulfreund, 1920