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Studienförderung in der Frühen Neuzeit. Das Luzerner Stipendienwesen in den Jahren 1550 bis 1650
(2008)
Anhand von Ratsprotokolle, Korrespondenzen und Testamenten wurde das Luzerner Stipendienwesen hinsichtlich seiner Funktionsweise, Intension und Wirkung untersucht für den Zeitraum 1550 bis 1650.Es stellt sich heraus, dass die Stipendien als obrigkeitliches Instrument der politischen und konfessionellen Stabilisierung des Standes Luzern dienten. Dabei erhielten in erster Linie die Söhne der Ratsherrengeschlechter die Studienförderung. D.h., dass eine Bildungsförderung eher armer Gesellschaftsschichten dem Anliegen der Statussicherung der neuen Luzerner Ratsgeschlechter entgegen stand. Dennoch wurden die obrigkeitlichen Stipendien nicht effektiv genutzt, wobei sie in Verbindung mit den (kirchlich-)privaten Studienstiftungen ein aufeinander aufbauendes Stipendiensystem ausbildeten, das die Grundausbildung und die Hochschulbildung zu mindest für einige Stipendiaten ermöglichte.
Evapotranspiration (ET) is one of the most important variables in hydrological studies. In the ET process, energy exchange and water transfer are involved. ET consists of transpiration and evaporation. The amount of plants transpiration dominates in ET. Especially in the forest regions, the ratio of transpiration to ET is in general 80-90 %. Meteorological variables, vegetation properties, precipitation and soil moisture are critical influence factors for ET generation. The study area is located in the forest area of Nahe catchment (Rhineland-Palatinate, Germany). The Nahe catchment is highly wooded. About 54.6 % of this area is covered by forest, with deciduous forest and coniferous forest are two primary types. A hydrological model, WaSiM-ETH, was employed for a long-term simulation from 1971-2003 in the Nahe catchment. In WaSiM-ETH, the potential evapotranspiration (ETP) was firstly calculated by the Penman-Monteith equation, and subsequently reduced according to the soil water content to obtain the actual evapotranspiration (ETA). The Penman-Monteith equation has been widely used and recommended for ETP estimation. The difficulties in applying this equation are the high demand of ground-measured meteorological data and the determination of surface resistance. A method combined remote sensing images with ground-measured meteorological data was also used to retrieve the ETA. This method is based on the surface properties such as surface albedo, fractional vegetation cover (FVC) and land surface temperature (LST) to obtain the latent heat flux (LE, corresponding to ETA) through the surface energy balance equation. LST is a critical variable for surface energy components estimation. It was retrieved from the TM/ETM+ thermal infrared (TIR) band. Due to the high-quality and cloudy-free requirements for TM/ETM+ data selection as well as the overlapping cycle of TM/ETM+ sensor is 16 days, images on only five dates are available during 1971-2003 (model ran) " May 15, 2000, July 05, 2001, July 19, August 04 and September 21 in 2003. It is found that the climate conditions of 2000, 2001 and 2003 are wet, medium wet and dry, respectively. Therefore, the remote sensing-retrieved observations are noncontinuous in a limited number over time but contain multiple climate conditions. Aerodynamic resistance and surface resistance are two most important parameters in the Penman-Monteith equation. However, for forest area, the aerodynamic resistance is calculated by a function of wind speed in the model. Since transpiration and evaporation are separately calculated by the Penman-Monteith equation in the model, the surface resistance was divided into canopy surface resistance rsc and soil surface resistance rse. rsc is related to the plants transpiration and rse is related to the bare soil evaporation. The interception evaporation was not taken into account due to its negligible contribution to ET rate under a dry-canopy (no rainfall) condition. Based on the remote sensing-retrieved observations, rsc and rse were calibrated in the WaSiM-ETH model for both forest types: for deciduous forest, rsc = 150 sm−1, rse = 250 sm−1; for coniferous forest, rsc = 300 sm−1, rse = 650 sm−1. We also carried out sensitivity analysis on rsc and rse. The appropriate value ranges of rsc and rse were determined as (annual maximum): for deciduous forest, [100,225] sm−1 for rsc and [50,450] sm−1 for rse; for coniferous forest, [225,375] sm−1 for rsc and [350,1200] sm−1 for rse. Due to the features of the observations that are in a limited number but contain multiple climate conditions, the statistical indices for model performance evaluation are required to be sensitive to extreme values. In this study, boxplots were found to well exhibit the model performance at both spatial and temporal scale. Nush-Sutcliffe efficiency (NSE), RMSE-observations standard deviation ratio (RSR), percent bias (PBIAS), mean bias error (MBE), mean variance of error distribution (S2d), index of agreement (d), root mean square error (RMSE) were found as appropriate statistical indices to provide additional evaluation information to the boxplots. The model performance can be judged as satisfactory if NSE > 0.5, RSR ≤ 0.7, PBIAS < -±12, MBE < -±0.45, S2d < 1.11, d > 0.79, RMSE < 0.97. rsc played a more important role than rse in ETP and ETA estimation by the Penman-Monteith equation, which is attributed to the fact that transpiration dominates in ET. The ETP estimation was found the most correlated to the relative humidity (RH), followed by air temperature (T), relative sunshine duration (SSD) and wind speed (WS). Under wet or medium wet climate conditions, ETA estimation was found the most correlated to T, followed by RH, SSD and WS. Under a water-stress condition, there were very small correlations between ETA and each meteorological variable.
Primo ist ein Softwareprodukt der Firma Ex Libris und ermöglicht eine einheitliche Einschlitz-Suche im Bibliothekskatalog, Artikeldatenbanken und anderen Datenquellen wie etwa digitalen Repositorien. An der Universitätsbibliothek Trier wird Primo eingeführt und die Artikeldatenbank Primo Central lizenziert mit dem primären Ziel, Zeitschriftenartikel und Bibliotheksbestand über eine Suchoberfläche zu erschließen. Im Folgenden wird insbesondere auf diese Implementierung eingegangen und einige Beobachtungen aus der Projektphase wiedergegeben. Die Arbeiten an Primo laufen bei uns momentan noch und eine öffentlichernVersion zur Ablösung des Online-Katalogs ist für 2012 geplant. Nach einer kurzen Einführung und Beschreibung der Funktionsweise von Primo werde ich folgende Thesen weiter ausführen: (1) Eine einheitliche Einschlitz-Suche wird aufgrund der Heterogenität derrnMetadatenqualität nur bedingt erreicht. (2) Die Auswertung großer Treffermengen wird mit Primo insbesondere durch diernFacettierungen in einem großen Masse unterstützt. Allerdings suggerieren diernFacettenwerte eine Vollständigkeit, die in dieser Weise nicht gewährleistet wird. Ebenfalls können Facettenwerte abhängig von der Sortierreihenfolge verloren gehen. (3) Die Darstellung der Daten kann man auf vielseitige Weise anpassen, so dass auch lokale Besonderheiten abgebildet werden können. Es wird als Beispiel gezeigt, wie wir die lokalen Signaturen in Primo zur Anzeige gebracht haben.
Dans les écoles fondamentales, le conseil de coopération offre aux élèves la possibilité d’apprendre et d’approfondir les premières étapes de la gestion démocratique. Dans un espace protégé, ils / elles apprennent à s’exprimer sur les thèmes les plus divers, à résoudre les conflits en se concentrant sur les solutions et à prendre des responsabilités. Les supports présentés ici ont pour objectif de vous aider à mettre en place et à mener à bien le conseil de coopération.
Dans les écoles secondaires, le conseil de coopération offre aussi aux élèves un espace pour exprimer leurs demandes et explorer, dans un processus démocratique, les potentiels d’amélioration pour la classe et l’école. Les supports ci-dessous vous aideront à préparer et à mener les réunions de manière autonome.
The main topic of this treatise is the solution of two problems from the general theory of linear partial differential equations with constant coefficients. While surjectivity criteria for linear partial differential operators in spaces of smooth functions over an open subset of euclidean space and distributions were proved by B. Malgrange and L. Hörmander in 1955, respectively 1962, concrete evaluation of these criteria is still a highly non-trivial task. In particular, it is well-known that surjectivity in the space of smooth functions over an open subset of euclidean space does not automatically imply surjectivity in the space of distributions. Though, examples for this fact all live in three or higher dimensions. In 1966, F. Trèves conjectured that in the two dimensional setting surjectivity of a linear partial differential operator on the smooth functions indeed implies surjectivity on the space of distributions. An affirmative solution to this problem is presented in this treatise. The second main result solves the so-called problem of (distributional) parameter dependence for solutions of linear partial differential equations with constant coefficients posed by J. Bonet and P. Domanski in 2006. It is shown that, in dimensions three or higher, this problem in general has a negative solution even for hypoelliptic operators. Moreover, it is proved that the two dimensional case is again an exception, because in this setting the problem of parameter dependence always has a positive solution.
COVID-19 was a harsh reminder that diseases are an aspect of human existence and mortality. It was also a live experiment in the formation and alteration of disease-related attitudes. Not only are these attitudes relevant to an individual’s self-protective behavior, but they also seem to be associated with social and political attitudes more broadly. One of these attitudes is Social Darwinism, which holds that a pandemic benefits society by enabling nature “to weed out the weak”. In two countries (N = 300, N = 533), we introduce and provide evidence for the reliability, validity, and usefulness of the Disease-Related Social Darwinism (DRSD) Short Scale measuring this concept. Results indicate that DRSD is meaningful related to other central political attitudes like Social Dominance Orientation, Authoritarianism and neoliberalism. Importantly, the scale significantly predicted people’s protective behavior during the Pandemic over and above general social Darwinism. Moreover, it significantly predicted conservative attitudes, even after controlling for Social Dominance Orientation.
Striving for sustainable development by combating climate change and creating a more social world is one of the most pressing issues of our time. Growing legal requirements and customer expectations require also Mittelstand firms to address sustainability issues such as climate change. This dissertation contributes to a better understanding of sustainability in the Mittelstand context by examining different Mittelstand actors and the three dimensions of sustainability - social, economic, and environmental sustainability - in four quantitative studies. The first two studies focus on the social relevance and economic performance of hidden champions, a niche market leading subgroup of Mittelstand firms. At the regional level, the impact of 1,645 hidden champions located in Germany on various dimensions of regional development is examined. A higher concentration of hidden champions has a positive effect on regional employment, median income, and patents. At the firm level, analyses of a panel dataset of 4,677 German manufacturing firms, including 617 hidden champions, show that the latter have a higher return on assets than other Mittelstand firms. The following two chapters deal with environmental strategies and thus contribute to the exploration of the environmental dimension of sustainability. First, the consideration of climate aspects in investment decisions is compared using survey data from 468 European venture capital and private equity investors. While private equity firms respond to external stakeholders and portfolio performance and pursue an active ownership strategy, venture capital firms are motivated by product differentiation and make impact investments. Finally, based on survey data from 443 medium-sized manufacturing firms in Germany, 54% of which are family-owned, the impact of stakeholder pressures on their decarbonization strategies is analyzed. A distinction is made between symbolic (compensation of CO₂-emissions) and substantive decarbonization strategies (reduction of CO₂-emissions). Stakeholder pressures lead to a proactive pursuit of decarbonization strategies, with internal and external stakeholders varying in their influence on symbolic and substantial decarbonization strategies, and the relationship influenced by family ownership.
Monatelange Wartezeiten auf einen ambulanten Psychotherapieplatz sind der Regelfall im deutschen Gesundheitssystem. Die Veränderung der Symptombelastung der Patienten in der Wartezeit ist bislang allerdings kaum empirisch untersucht worden. In der vorliegenden Arbeit wurden an einer Stichprobe ambulanter Psychotherapiepatienten die Ausprägungen und Veränderungen der allgemeinen psychischen Symptombelastung während der durchschnittlich sechsmonatigen Wartezeit auf den Psychotherapieplatz untersucht. Zudem wurde überprüft, mit welchen Merkmalen die Symptombelastungen zum Zeitpunkt der Anmeldung zur Therapie und zum Zeitpunkt des Erstgesprächs sowie ihre Veränderungen in der Wartezeit zusammenhängen. Die dabei untersuchten Persönlichkeitsmerkmale wurden aus theoretischen Rahmenmodellen abgeleitet. Hierzu gehören die aktionale Entwicklungspsychologie, das handlungstheoretische Partialmodell der Persönlichkeit mit der darin eingeordneten Vertrauens-Trias und das Androgynie-Modell der psychischen Gesundheit. Nach einem direkten Veränderungskriterium zeigten 48 % der Patienten in der Wartezeit keine bedeutsame Veränderung, 29 % eine Verbesserung und 23 % eine Verschlechterung. Durch die bei der Anmeldung erfassten Persönlichkeitsmerkmale konnten Verbesserungen, Verschlechterungen und gleichbleibende Symptombelastungen in der Wartezeit anhand einer multinomialen logistischen Regressionsanalyse für 60 % der Patienten korrekt vorausgesagt werden. Eine traditionelle normative Geschlechtsrollen-Orientierung stellt einen negativen Prädiktor für eine Verbesserung dar. Soziales Vertrauen konnte Verschlechterungen negativ vorhersagen. Bei Hoffnungslosigkeit handelt es sich um einen marginal negativen Prädiktor für eine Verbesserung. Ein hoch ausgeprägtes Selbstkonzept eigener Fähigkeiten ist ein positiver Prädiktor für eine Verschlechterung. Hinsichtlich der soziodemografischen und störungsbezogenen Merkmale konnten das Alter, das Geschlecht und die Anzahl der Diagnosen die Veränderungen der Symptombelastung in der Wartezeit zu 54 % korrekt vorhersagen. Das Alter ist ein positiver Prädiktor für eine Verschlechterung. Weibliches Geschlecht und die Anzahl an Diagnosen sind negative Prädiktoren für eine Verbesserung. Darüber hinaus wurden differenzierte Zusammenhänge zwischen den Persönlichkeitsmerkmalen und der Symptombelastung exploratorisch untersucht.
Synergieeffekte und Kollaboration bei e-Learning-Anwendungen in selbstorganisierenden Computernetzen
(2009)
In den letzten Jahren haben sich mehrere neue Netzklassen im Bereich der Verteilten Systeme etabliert. Diese können unter Ausnutzung von Selbstorganisationsprinzipien und verschiedener kollaborativer Aspekte viele der netzinhärenten Probleme wie Skalierbarkeit, Latenz- und Lastverteilungsbetrachtungen sowie Konsistenzwahrung entschärfen. Gleichzeitig kann die Nutzung entsprechender Prinzipien zu positiven Synergieeffekten führen, die von den verschiedenen auf diesen Netzen aufsetzten Applikationsdomänen genutzt werden können. Von besonderer Bedeutung sind diese Aspekte für die beiden neuartigen Netzklassen der Multi-Hop Adhoc-Netze (MANETs) und der globalen virtuellen Umgebungen (MMVEs). Beiden Netzklassen ist gemeinsam, dass sie aufgrund der erwähnten Problemstellungen nicht mit traditionellen verteilten Architekturen, wie zentralistischen und monolithischen Systemen, umgesetzt werden können. Hier muss ein Paradigmenwechsel hin zu dezentralen, selbstorganisierenden Systemstrukturen erfolgen, um den angesprochenen Herausforderungen zu begegnen. Die erste in dieser Arbeit untersuchte Netzklasse der MANETs zeichnet sich dadurch aus, dass sie Nutzern erlaubt, immer und überall auf Ihre Daten zugreifen zu können und mit der vor Ort vorhandenen Infrastruktur transparent zu kommunizieren. Dabei erfolgen die Daten-zugriffe vermehrt über immer kleiner werdende mobile Endgeräte, die sowohl aufgrund ihrer inhärenten Mobilität als auch ihrer eingeschränkten Ressourcen daran angepasste Netzstrukturen erfordern. Die neuartige Netzklasse der MMVEs dagegen soll Dateninhalte in einem dreidimensionalen Rahmen und damit nativ und intuitiver als die vorherrschende zweidimensionale Darstellung, wie z.B. im Internet, präsentieren. Der Datenzugriff erfolgt hier meist über eine virtuelle Benutzerrepräsentation " einen Avatar. MMVEs basieren zwar im Vergleich zu MANETs in der Regel auf physisch verlässlichen Netzen, benötigen aber aufgrund der massiven Verteilung und der großen Nutzerzahlen neue Netzwerkarchitekturen. Die Anwendungsdomäne e-Learning eignet sich in diesem Zusammenhang besonders gut für wissenschaftliche Untersuchungen, da hier eine ähnliche Entwicklung beobachtbar ist, wie bei den eingangs erwähnten Netzklassen. Genauso wie mobile Endgeräte immer kleiner und ubiquitär verfügbar werden und das Internet praktisch an jedem Ort der Welt mit hoher Bandbreite nutzbar ist, finden e-Learning Inhalte immer mehr Einzug in das tägliche Leben. Während sie früher nur eine vernachlässigbare Ergänzung zu etablierten Schulungsformen darstellten, die mehr oder weniger invasiv und starr zentral administriert wurde, steigt Ihre Bedeutung besonders im Zusammenhang mit neuen Zugangsformen täglich. Besonders das Bedürfnis an Schulen oder Universitäten sowie bei der innerbetrieblichen Aus- und Weiterbildung, immer und überall verteilt, nativ und transparent auf entsprechende Lehr- und Lerninhalte zugreifen zu können, steigt mit dem wachsenden und teilweise rein wirtschaftlich bedingten Bedarf nach einer qualitativ hohen, kontinuierlichen gesellschafts- und technikdurchdringenden Grund- und Weiterbildung. Die geforderte Transparenz und Ubiquität kann für die angesprochene Anwendungsdomäne dadurch erreicht werden, dass spezielle, auf die neuartigen verteilten Netzstrukturen abgestimmte, Applikationen entwickelt werden, die die netzinhärenten Selbstorganisations-prinzipien explizit ausnutzen. Eine wichtige Fragestellung in diesem Zusammenhang ist, welche Auswirkungen ein solcher Paradigmenwechsel auf die Qualität der Wissens-vermittlung und der Inhalte hat. Erste Evaluationen mit prototypischen Applikationen haben gezeigt, dass dieser Wechsel problemlos möglich ist. Dabei spiegeln auftretende Synergie-effekte die Abbildung auf soziale Netze wieder, die beiden Aspekten inhärent zugrunde liegt und einen Mehrwert erzeugen, der die dabei auftretenden technischen Herausforderungen und Probleme relativiert. Entsprechende Effekte lassen sich sogar noch weiter verstärken, indem kollaborative Aspekte sowohl auf Applikationsebene als auch in den darunter liegenden Basisstrukturen ausgenutzt werden. Die vorliegende Arbeit soll diese Annahmen durch adäquate Beispiele aus beiden Bereichen (MANETs und MMVEs) aus verschiedenen Perspektiven beleuchten und anhand von beispielhaften Anwendungen und darauf aufbauende Evaluationen den Synergiegewinn von e-Learning Applikationen und mögliche kollaborative Aspekte in diesem Umfeld aufzeigen.
Systemische Resilienz
(2019)
In dem Gebiet der Informationsextraktion angesiedelt kombiniert diese Arbeit mehrere Verfahren aus dem Bereich des maschinellen Lernens. Sie stellt einen neuen Algorithmus vor, der teil-überwachtes Lernen mit aktivem Lernen verknüpft. Ausgangsbasis ist die Analyse der Daten, indem sie in mehrere Sichten aufgeteilt werden. Hier werden die Eingaben verschiedener Personen unterteilt. Jeweils getrennt voneinander erzeugt der Algorithmus mittels Klassifizierern Modelle, die aus den individuellen Auszeichnungen der Personen aufgebaut werden. Um die dafür benötigte Datenmenge zu erhalten wird Crowdsourcing genutzt, dass es ermöglicht eine große Anzahl an Personen zu erreichen. Die Personen erhalten die Aufgabe, Texte zu annotieren. Einerseits wird dies initial für einen historischen Textkorpus vorgenommen. Dabei wird aufgeführt, welche Schritte notwendig sind, um die Annotationsaufgabe in Crowdsourcing-Portalen zur Bearbeitung anzubieten und durchzuführen. Andererseits wird ein aktueller Datensatz von Kurznachrichten genutzt. Der Algorithmus wird auf diese Beispieldatensätze angewandt. Durch Experimente wird die Ermittlung der optimalen Parameterauswahl durchgeführt. Außerdem werden die Ergebnisse mit den Resultaten bisheriger Algorithmen verglichen.
Formulations of macrocyclic lactone anthelmintics such as moxidectin are regularly administered to sheep to combat parasites. A disadvantage of these pharmaceuticals are their side effects on non-target organisms when entering the environment. Little is known about anthelmintic effects on plant reproduction and whether the effects depend on environmental factors. For ecological and methodological reasons, we aimed at testing whether temperature affects the efficacy of a common moxidectin-based formulation on seed germination. We carried out a germination experiment including three typical species of temperate European grasslands (Centaurea jacea, Galium mollugo, Plantago lanceolata). We applied three temperature regimes (15/5, 20/10, 30/20°C), and a four-level dilution series (1:100–1:800) of formulated moxidectin (i.e., Cydectin oral drench). These solutions represent seed-anthelmintic contacts in the digestive tract of sheep shortly after deworming. In addition, a control was carried out with purified water only. We regularly counted emerging seedlings and calculated final germination percentage, mean germination time and synchrony of germination. Formulated moxidectin significantly reduced percentage, speed and synchrony of germination. A 1:100 dilution of the formulation reduced germination percentage by a quarter and increased mean germination time by six days compared to the control. Temperature moderated effects of the anthelmintic drug on germination in all response variables and all species, but in different patterns and magnitudes (significant anthelmintic x temperature x species interactions). In all response variables, the two more extreme temperature regimes (15/5, 30/20°C) led to the strongest effects of formulated moxidectin. With respect to germination percentage, G. mollugo was more sensitive to formulated moxidectin at the warmest temperature regime, whereas P. lanceolata showed the highest sensitivity at the coldest regime. This study shows that it is important to consider temperature dependencies of the effects of pharmaceuticals on seed germination when conducting standardised germination experiments.
The temporal stability of psychological test scores is one prerequisite for their practical usability. This is especially true for intelligence test scores. In educational contexts, high stakes decisions with long-term consequences, such as placement in special education programs, are often based on intelligence test results. There are four different types of temporal stability: mean-level change, individual-level change, differential continuity, and ipsative continuity. We present statistical methods for investigating each type of stability. Where necessary, the methods were adapted for the specific challenges posed by intelligence research (e.g., controlling for general intelligence in lower order test scores). We provide step-by-step guidance for the application of the statistical methods and apply them to a real data set of 114 gifted students tested twice with a test-retest interval of 6 months.
• Four different types of stability need to be investigated for a full picture of temporal stability in psychological research
• Selection and adaption of the methods for the use in intelligence research
• Complete protocol of the implementation
Climate fluctuations and the pyroclastic depositions from volcanic activity both influence ecosystem functioning and biogeochemical cycling in terrestrial and marine environments globally. These controlling factors are crucial for the evolution and fate of the pristine but fragile fjord ecosystem in the Magellanic moorlands (~53°S) of southernmost Patagonia, which is considered a critical hotspot for organic carbon burial and marine bioproductivity. At this active continental margin in the core zone of the southern westerly wind belt (SWW), frequent Plinian eruptions and the extremely variable, hyper-humid climate should have efficiently shaped ecosystem functioning and land-to-fjord mass transfer throughout the Late Holocene. However, a better understanding of the complex process network defining the biogeochemical cycling at this land-to-fjord continuum principally requires a detailed knowledge of substrate weathering and pedogenesis in the context of the extreme climate. Yet, research on soils, the ubiquitous presence of tephra and the associated chemical weathering, secondary mineral (trans)formation and organic matter (OM) turnover processes is rare in this remote region. This complicates an accurate reconstruction of the ecosystem´s potentially sensitive response to past environmental impacts, including the dynamics of Late Holocene land-to-fjord fluxes as a function of volcanic activity and strong hydroclimate variability.
Against this background, this PhD thesis aims to disentangle the controlling factors that modulate the terrigenous element mobilization and export mechanisms in the hyper-humid Patagonian Andes and assesses their significance for fjord primary productivity over the past 4.5 kyrs BP. For the first time, distinct biogeochemical characteristics of the regional weathering system serve as major criterion in paleoenvironmental reconstruction in the area. This approach includes broad-scale mineralogical and geochemical analyses of basement lithologies, four soil profiles, volcanic ash deposits, the non-karst stalagmite MA1 and two lacustrine sediment cores. In order to pay special attention to the possibly important temporal variations of pedosphere-atmosphere interaction and ecological consequences initiated by volcanic eruptions, the novel data were evaluated together with previously published reconstructions of paleoclimate and paleoenvironmental conditions.
The devastative high-tephra loading of a single eruption from Mt. Burney volcano (MB2 at 4.216 kyrs BP) sustainably transformed this vulnerable fjord ecosystem, while acidic peaty Andosols developed from ~2.5 kyrs BP onwards after the recovery from millennium-scale acidification. The special setting is dominated by most variable redox-pH conditions, profound volcanic ash weathering and intense OM turnover processes, which are closely linked and ultimately regulated by SWW-induced water-level fluctuations. Constant nutrient supply though sea spray deposition represents a further important control on peat accumulation and OM turnover dynamics. These extreme environmental conditions constrain the biogeochemical framework for an extended land-to-fjord export of leachates comprising various organic and inorganic colloids (i.e., Al-humus complexes and Fe-(hydr)oxides). Such tephra- and/or Andosol-sourced flux contains high proportions of terrigenous organic carbon (OCterr) and mobilized essential (micro)nutrients, e.g., bio-available Fe, that are beneficial for fjord bioproductivity. It can be assumed that this supply of bio-available Fe produced by specific Fe-(hydr)oxide (trans)formation processes from tephra components may outlast more than 6 kyrs and surpasses the contribution from basement rock weathering and glacial meltwaters. However, the land-to-fjord exports of OCterr and bio-available Fe occur mostly asynchronous and are determined by the frequency and duration of redox cycles in soils or are initiated by SWW-induced extreme weather events.
The verification of (crypto)tephra layers embedded stalagmite MA1 enabled the accurate dating of three smaller Late Holocene eruptions from Mt. Burney (MB3 at 2.291 kyrs BP and MB4 at 0.853 kyrs BP) and Aguilera (A1 at 2.978 kyrs BP) volcanoes. Irrespective of the improvement of the regional tephrochronology, the obtained precise 230Th/U-ages allowed constraints on the ecological consequences caused by these Plinian eruptions. The deposition of these thin tephra layers should have entailed a very beneficial short-term stimulation of fjord bioproductivity with bio-available Fe and other (micro)nutrients, which affected the entire area between 52°S and 53°S 30´, respectively. For such beneficial effects, the thickness of tephra deposited to this highly vulnerable peatland ecosystem should be below a threshold of 1 cm.
The Late Holocene element mobilization and land-to-fjord transport was mainly controlled by (i) volcanic activity and tephra thickness, (ii) SWW-induced and southern hemispheric climate variability and (iii) the current state of the ecosystem. The influence of cascading climate and environmental impacts on OCterr and Fe-(hydr)oxide fluxes to can be categorized by four individual, in part overlapping scenarios. These different scenarios take into account the previously specified fundamental biogeochemical mechanisms and define frequently recurring patterns of ecosystem feedbacks governing the land-to-fjord mass transfer in the hyper-humid Patagonian Andes on the centennial-scale. This PhD thesis provides first evidence for a primarily tephra-sourced, continuous and long-lasting (micro)nutrient fertilization for phytoplankton growth in South Patagonian fjords, which is ultimately modulated by variations in SWW-intensity. It highlights the climate sensitivity of such critical land-to-fjord element transport and particularly emphasizes the important but so far underappreciated significance of volcanic ash inputs for biogeochemical cycles at active continental margins.
Das Working Paper beleuchtet den Themenbereich Beschäftigung und wirtschaftliche Entwicklung und arbeitet Herausforderungen für die Raumentwicklung der Großregion ab. Insbesondere legt es einen Fokus auf die Industriegeschichte sowie die Beschäftigung und grenzüberschreitende Arbeit in der Großregion.
Das Working Paper beleuchtet den Themenbereich‚Demografie und Migration und arbeitet Herausforderungen für die Raumentwicklung der Großregion ab. Insbesondere legt es einen Fokus auf die grenzüberschreitende Wohnmobilität an den Grenzen des Großherzogtums; die Bevölkerungsalterung und die Sicherung der Daseinsvorsorge im Gesundheitsbereich in ländlichen Gebieten.
Mit diesem Territorial Science Echo werden wesentliche Facetten von Governance beleuchtet, die sich für die künftige Entwicklung der Großregion als relevant erweisen können. Es wird insbesondere dargestellt, wie thematische Kooperationen und Konflikte zur der Etablierung von Governance Strukturen beitragen. Das Paper setzt sich mit den Themen Governance im Allgemeinen, Partizipation und Wohnen sowie den Außenbeziehungen der Großregion auseinander, formuliert wesentliche Herausforderungen und Empfehlungen, und ist somit als Anregung im fachlichen Diskurs um die weitere Gestaltung des Raumentwicklungskonzeptes der Großregion zu verstehen.
Das Working Paper beleuchtet den Themenbereich‚ Mobilität und Verkehr und arbeitet Herausforderungen für die Raumentwicklung der Großregion ab. Insbesondere legt es einen Fokus auf die Territoriale Verteilung der grenzüberschreitenden Arbeitnehmerströme und deren Abhängigkeit vom Auto innerhalb der Großregion sowie den Einfluss von EU Politik auf Herausforderungen des grenzüberschreitenden Verkehrs.
Das Working Paper beleuchtet den Themenbereich Energie und arbeitet Herausforderungen für die Raumentwicklung der Großregion ab. Es diskutiert den Begriff der Energiewende und legt einen Fokus auf Energiesysteme und –träger, insbesondere den Ausbau der Windkraft und Energiegewinnung aus Biomasse im Zusammenhang mit der Entwicklung fossil-atomarer Energiequellen in Deutschland und Frankreich.
Cinema programming, the composition of films to make a specific "show," remains a neglected way to research the relation between audiences and film form. As a mode of exhibition " advertised, promoted, and circulating in the public sphere even before an audience is gathered " the program can be seen as an active social relation between cinema managers and their audiences. Changes in the composition of film programs, in my case the years before the First World War in Mannheim, Germany, are thus not taken as part of a teleological evolution of film form, but instead reveal emerging practices of cinema-going, a changing relation among showmen, distributors, audiences, and the city they are all part of. The category of "the audience" becomes a compliment to narrative, economic and technical influences. Selecting the city of Mannheim further allows me to draw upon the pioneering German sociological study of cinema audiences, conducted there by Emilie Altenloh in 1911 and 1912. Thus, I am able to compare her survey data to the film programs that were actually advertised and offered to the public at the time, and also include knowledge of the social history of the city, to approximate a description of the historical audiences she studied. Here I follow the findings of Miriam Hansen and Heide Schlüpmann, who both stress the importance of the female audience in Imperial Germany. I account for a reciprocal relation between female spectators and the film industry- local programming practice to describe the transitional period from the short film programme of the "cinema of attractions" to the dominance of the long feature film, i.e. from 1906-1918. Looking closely at the advertised programmes of Mannheim I show that almost all of the first multiple-reel feature films deal with women- topics, i.e. with the fate and fortune of women, concluding that the presence of women in the audience helped established the long feature as central to the institutionalized cinema program. The film program and the specific feature films represented female identity on the screen, responding to the perceived wishes and needs of the women who gathered as audiences. Taking this "program analysis" approach, because it provides a synopsis of the social relation between audience, industry, and film form, is a valuable tool for comparing the social place of film comparatively, across many films, and potentially across regions, countries, and cultures.
The benefits of prosocial power motivation in leadership: Action orientation fosters a win-win
(2023)
Power motivation is considered a key component of successful leadership. Based on its dualistic nature, the need for power (nPower) can be expressed in a dominant or a prosocial manner. Whereas dominant motivation is associated with antisocial behaviors, prosocial motivation is characterized by more benevolent actions (e.g., helping, guiding). Prosocial enactment of the power motive has been linked to a wide range of beneficial outcomes, yet less has been investigated what determines a prosocial enactment of the power motive. According to Personality Systems Interactions (PSI) theory, action orientation (i.e., the ability to self-regulate affect) promotes prosocial enactment of the implicit power motive and initial findings within student samples verify this assumption. In the present study, we verified the role of action orientation as an antecedent for prosocial power enactment in a leadership sample (N = 383). Additionally, we found that leaders personally benefited from a prosocial enactment strategy. Results show that action orientation through prosocial power motivation leads to reduced power-related anxiety and, in turn, to greater leader well-being. The integration of motivation and self-regulation research reveals why leaders enact their power motive in a certain way and helps to understand how to establish a win-win situation for both followers and leaders.
The present thesis is devoted to a construction which defies generalisations about the prototypical English noun phrase (NP) to such an extent that it has been termed the Big Mess Construction (Berman 1974). As illustrated by the examples in (1) and (2), the NPs under study involve premodifying adjective phrases (APs) which precede the determiner (always realised in the form of the indefinite article a(n)) rather than following it.
(1) NoS had not been hijacked – that was too strong a word. (BNC: CHU 1766)
(2) He was prepared for a battle if the porter turned out to be as difficult a customer as his wife. (BNC: CJX 1755)
Previous research on the construction is largely limited to contributions from the realms of theoretical syntax and a number of cursory accounts in reference grammars. No comprehensive investigation of its realisations and uses has as yet been conducted. My thesis fills this gap by means of an exhaustive analysis of the construction on the basis of authentic language data retrieved from the British National Corpus (BNC). The corpus-based approach allows me to examine not only the possible but also the most typical uses of the construction. Moreover, while previous work has almost exclusively focused on the formal realisations of the construction, I investigate both its forms and functions.
It is demonstrated that, while the construction is remarkably flexible as concerns its possible realisations, its use is governed by probabilistic constraints. For example, some items occur much more frequently inside the degree item slot than others (as, too and so stand out for their particularly high frequency). Contrary to what is assumed in most previous descriptions, the slot is not restricted in its realisation to a fixed number of items. Rather than representing a specialised structure, the construction is furthermore shown to be distributed over a wide range of possible text types and syntactic functions. On the other hand, it is found to be much less typical of spontaneous conversation than of written language; Big Mess NPs further display a strong preference for the function of subject complement. Investigations of the internal structural complexity of the construction indicate that its obligatory components can optionally be enriched by a remarkably wide range of optional (if infrequent) elements. In an additional analysis of the realisations of the obligatory but lexically variable slots (head noun and head of AP), the construction is highlighted to represent a productive pattern. With the help of the methods of Collexeme Analysis (Stefanowitsch and Gries 2003) and Co-varying Collexeme Analysis (Gries and Stefanowitsch 2004b, Stefanowitsch and Gries 2005), the two slots are, however, revealed to be strongly associated with general nouns and ‘evaluative’ and ‘dimension’ adjectives, respectively. On the basis of an inspection of the most typical adjective-noun combinations, I identify the prototypical semantics of the Big Mess Construction.
The analyses of the constructional functions centre on two distinct functional areas. First, I investigate Bolinger’s (1972) hypothesis that the construction fulfils functions in line with the Principle of Rhythmic Alternation (e.g. Selkirk 1984: 11, Schlüter 2005). It is established that rhythmic preferences co-determine the use of the construction to some extent, but that they clearly do not suffice to explain the phenomenon under study. In a next step, the discourse-pragmatic functions of the construction are scrutinised. Big Mess NPs are demonstrated to perform distinct information-structural functions in that the non-canonical position of the AP serves to highlight focal information (compare De Mönnink 2000: 134-35). Additionally, the construction is shown to place emphasis on acts of evaluation. I conclude the construction to represent a contrastive focus construction.
My investigations of the formal and functional characteristics of Big Mess NPs each include analyses which compare individual versions of the construction to one another (e.g. the As Big a Mess, Too Big a Mess and So Big a Mess Constructions). It is revealed that the versions are united by a shared core of properties while differing from one another at more abstract levels of description. The question of the status of the constructional versions as separate constructions further receives special emphasis as part of a discussion in which I integrate my results into the framework of usage-based Construction Grammar (e.g. Goldberg 1995, 2006).
In den letzten Jahren führte die intensive Forschung im Bereich der Hochleistungskommunikationsnetze zu kontinuierlichen technologischen Verbesserungen. Gegenwärtig ist eine schnell wachsende Nachfrage nach mobilen Kommunikationssystemen wie Mobiltelefonen oder kabellosen Computernetzen zu verzeichnen. Parallel zu diesen Entwicklungen stiegen die Anforderungen an die Methoden zur Leistungsanalyse derartiger Systeme. Die Warteschlangentheorie stellt klassische Modelle zur Analyse von Kommunikationsnetzen bereit. Ein Bereich in der modernen Warteschlangentheorie sind die Matrixanalytischen Methoden. Hier konzentriert sich die Forschung auf den Batch Markovian Arrival Process (BMAP), welcher äquivalent zu Neuts Versatile Markovian Point Process ist, und Warteschlangensysteme mit diesem Ankunftsprozeß. Der BMAP ist eine Verallgemeinerung des Poisson Prozesses, des Markov Modulated Poisson Process (MMPP) und des Markovian Arrival Process (MAP). Das BMAP/G/1 Warteschlangensystem wurde analysiert von Ramaswami (damals noch mit der Bezeichnung N/G/1) und Lucantoni. Weitere Varianten wurden später untersucht. Die bisher betrachteten Ankunftsprozesse sind räumlich homogen und somit unabhängig vom aktuellen Zustand des Warteschlangensystems. In modernen Kommunikationsnetzen, wie z.B. ATM, kann jedoch ein dynamisches Routing erfolgen, so daß der Ankunftsstrom in einen Knoten vom aktuellen Zustand dieses Knotens abhängt. Dies war unser Ausgangspunkt für die Definition eines Level-abhängigen BMAPs und die Analyse des BMAP/G/1 Warteschlangensystems mit Level-abhängigen Ankünften. Letzteres stellt eine Verallgemeinerung des klassischen BMAP/G/1 Warteschlangensystems dar. Es umfaßt auch das BMAP/G/1 Warteschlangensystem mit beschränktem Warteraum. Im ersten Teil dieser Arbeit definieren wir einen Level-abhängigen BMAP und leiten wichtige Eigenschaften der Generatormatrix und der Übergangswahrscheinlichkeiten her. Wir zeigen, daß die Übergangsmatrix des Level-abhängigen BMAPs die Vorwärts- und Rückwärtsdifferentialgleichungen erfüllt und somit als Matrixexponentialfunktion der Generatormatrix darstellbar ist. Der zweite Teil befaßt sich mit der Analyse des BMAP/G/1 Warteschlangensystems mit Level-abhängigen Ankünften. Dieses Warteschlangensystem und die zugehörigen stochastischen Prozesse werden in Kapitel 2 eingeführt. Um die Grenzverteilung der Warteschlangenlänge zu bestimmen, verwenden wir die Methode der eingebetteten Markov Kette. In Kapitel 3 bestimmen wir die Einträge der Übergangsmatrix der eingebetteten Markov Kette und die mittlere Zahl Ankünfte während einer Bedienzeit. Stabilitätsbedingungen für das BMAP/G/1 Warteschlangensystem mit Level- abhängigen Ankünften werden durch Anwendung eines verallgemeinerten Foster Kriteriums hergeleitet. Im Level-unabhängigen Fall spielt die Fundamentalperiodenmatrix G die Hauptrolle bei der Bestimmung der Gleichgewichtsverteilung. In unserem Fall hängen die Fundamentalperioden vom Anfangslevel k ab. Daher erhalten wir verschiedene Fundamentalperiodenmatrizen G ( k ) für alle Level k >= 1 . Wir leiten zwei Algorithmen zur Berechnung dieser Matrizen her. Weiterhin zeigen wir, daß die Vektoren der mittleren Anzahlen Bedienabschlüsse während einer Fundamentalperiode die eindeutige Lösung eines unendlich - dimensionalen Systems linearer Gleichungen bilden. Mit diesen Ergebnissen kann die stationäre Verteilung der Warteschlangenlänge zu Bedienabschlußzeitpunkten bestimmt werden. Wir wenden ein Ergebnis aus der Theorie der Semi-Markov Prozesse an, um die Gleichgewichtswahrscheinlichkeiten für Level 0 zu erhalten. Um die Gleichgewichtswahrscheinlichkeiten der übrigen Level zu berechnen, verallgemeinern wir die Formel von Ramaswami. Die Grenzverteilung der Warteschlangenlänge zu beliebigen Zeitpunkten wird unter Verwendung des Hauptsatzes der Erneuerungstheorie hergeleitet. Im dritten Teil betrachten wir einige Spezialfälle. Zunächst nehmen wir an, daß der Phasenprozeß Level-unabhängig sei. In diesem Fall können wir einige unserer Ergebnisse erweitern. Insbesondere leiten wir eine stärkere Stabilitätsbedingung her. Wir beenden diesen Teil, indem wir zeigen, daß unsere Ergebnisse mit den für das klassische BMAP/G/1 Warteschlangensystem und das BMAP/G/1 Warteschlangensystem mit beschränktem Warteraum übereinstimmen. Zum Abschluß dieser Arbeit geben wir einige Hinweise für weitere Forschungen.
The changing views on the evolutionary relationships of extant Salamandridae (Amphibia: Urodela)
(2018)
The phylogenetic relationships among members of the family Salamandridae have been repeatedly investigated over the last 90 years, with changing character and taxon sampling. We review the changing composition and the phylogenetic position of salamandrid genera and species groups and add a new phylogeny based exclusively on sequences of nuclear genes. Salamandrina often changed its position depending on the characters used. It was included several times in a clade together with the primitive newts (Echinotriton, Pleurodeles, Tylototriton) due to their seemingly ancestral morphology. The latter were often inferred as a monophyletic clade. Respective monophyly was almost consistently established in all molecular studies for true salamanders (Chioglossa, Lyciasalamandra, Mertensiella, Salamandra), modern Asian newts (Cynops, Laotriton, Pachytriton, Paramesotriton) and modern New World newts (Notophthalmus, Taricha). Reciprocal non-monophyly has been established through molecular studies for the European mountain newts (Calotriton, Euproctus) and the modern European newts (Ichthyosaura, Lissotriton, Neurergus, Ommatotriton, Triturus) since Calotriton was identified as the sister lineage of Triturus. In pre-molecular studies, their respective monophyly had almost always been assumed, mainly because a complex courtship behaviour shared by their respective members. Our nuclear tree is nearly identical to a mito-genomic tree, with all but one node being highly supported. The major difference concerns the position of Calotriton, which is no longer nested within the modern European newts. This has implications for the evolution of courtship behaviour of European newts. Within modern European newts, Ichthyosaura and Lissotriton changed their position compared to the mito-genomic tree. Previous molecular trees based on seemingly large nuclear data sets, but analysed together with mitochondrial data, did not reveal monophyly of modern European newts since taxon sampling and nuclear gene coverage was too poor to obtain conclusive results. We therefore conclude that mitochondrial and nuclear data should be analysed on their own.
The last decades of stress research have yielded substantial advancements highlighting the importance of the phenomenon for basic psychological functions as well as physical health and well-being. Progress in stress research heavily relies on the availability of suitable and well validated laboratory stressors. Appropriate laboratory stressors need to be able to reliably provoke a response in the relevant parameters and be applicable in different research settings or experimental designs. This thesis focuses on the Cold Pressor Test (CPT) as a stress induction technique. Three published experiments are presented that show how the advantages of the CPT can be used to test stress effects on memory processes and how some of its disadvantages can be met by a simple modification that retains its feasibility and validity. The first experiment applies the CPT in a substantial sample to investigate the consolidation effects of post-learning sympathetic arousal. Stressed participants with high increases in heart rate during the CPT showed enhanced memory performance one day after learning compared to both the warm water control group and low heart rate responders. This finding suggests that beta-adrenergic activation elicited shortly after learning enhances memory consolidation and that the CPT induced heart rate response is a predictor for this effect. Moreover, the CPT proved to be an appropriate stressor to test hypothesis about endogenous adrenergic effects on memory processes. The second experiment addresses known practical limitations of the standard dominant hand CPT protocol. A bilateral feet CPT modification is presented, the elicited neuroendocrine stress response assessed and validated against the standard CPT in a within-subjects design. The bilateral feet CPT elicited a substantial neuroendocrine stress response. Moreover, with the exception of blood pressure responses, all stress parameters were enhanced compared to the standard CPT. This shows that the bilateral feet CPT is a valid alternative to the standard CPT. The third experiment further validates the bilateral feet CPT and its corresponding control procedure by employing it in a typical application scenario. Specifically, the bilateral feet CPT was used to modulate retrieval of event files in a distractor-response binding paradigm that required lateralized bimanual responses. Again, the bilateral feet CPT induced significant increases in heart rate, blood pressure and cortisol, no such increases could be observed in the warm water control condition. Moreover, stressed participants showed diminished retrieval compared to controls. These results provide further evidence for the feasibility and validity of the bilateral feet CPT and its warm water control procedure. Together the experiments presented here highlight the usefulness of the CPT as a tool in psychophysiological stress research. It is especially well suited to test hypothesis concerning stress effects on memory processes and its applicability can be further increased by the bilateral feet modification.
The Constitution of Latvia
(2004)
The article offers a concise view on the constitution of the Baltic state of Latvia. After an introduction focusing on constitutional history, the author explores basic principles and human rights in the text of the constitution and explains the main constitutional bodies and their functions in legislative, executive and judiciary. Chapters on citizenship and religious rights round up this introduction to the Latvian Constitution.
Although geographically it belongs to Europe, as far as the constitutionality control of the statutory provisions is concerned, Greece follows the American system. That means that there is no Constitutional Court and, on the contrary, every court (even those of first instance) are entitled, and indeed obliged, to control the constitutionality of the laws (Articles 87 par. 2 and 93 par. 4 of the Greek Constitution). The Greek Courts examine only the substantial and not the formal constitutionality of the statutory provisions. If a court comes to the result of the unconstitutionality, then the statutory provision is not annulled and removed from the legal order, but it is not applied by the court in the relevant court procedure. The only – rather rare – case where a statutory provision is erga omnes annulled is when this is ordered by a decision of the Highest Special Court (Article 100 of the Greek Constitution), following a disagreement between two of the three highest Courts, namely between Symvoulio tis Epikrateias (highest Administrative Court), Areios Pagos (Cassations Court in Civil and Criminal procedures) and Elegtiko Synedrio (Court of Audit).
The presentation is going to examine the origins of the Greek system of the constitutionality control. It will also focus on the advantages and disadvantages of the Greek system and on the scientific and political discussion. Last but not least, the presentation will examine the role of the Council of State, which, although formally not a Constitutional Court, in practice issues the vast majority of the court decisions which accept the unconstitutionality of statutory provisions.
Academic achievement is a central outcome in educational research, both in and outside higher education, has direct effects on individual’s professional and financial prospects and a high individual and public return on investment. Theories comprise cognitive as well as non-cognitive influences on achievement. Two examples frequently investigated in empirical research are knowledge (as a cognitive determinant) and stress (as a non-cognitive determinant) of achievement. However, knowledge and stress are not stable, what raises questions as to how temporal dynamics in knowledge on the one hand and stress on the other contribute to achievement. To study these contributions in the present doctoral dissertation, I used meta-analysis, latent profile transition analysis, and latent state-trait analysis. The results support the idea of knowledge acquisition as a cumulative and long-term process that forms the basis for academic achievement and conceptual change as an important mechanism for the acquisition of knowledge in higher education. Moreover, the findings suggest that students’ stress experiences in higher education are subject to stable, trait-like influences, as well as situational and/or interactional, state-like influences which are differentially related to achievement and health. The results imply that investigating the causal networks between knowledge, stress, and academic achievement is a promising strategy for better understanding academic achievement in higher education. For this purpose, future studies should use longitudinal designs, randomized controlled trials, and meta-analytical techniques. Potential practical applications include taking account of students’ prior knowledge in higher education teaching and decreasing stress among higher education students.
The daily dose of health information: A psychological view on the health information seeking process
(2021)
The search for health information is becoming increasingly important in everyday life, as well as socially and scientifically relevant Previous studies have mainly focused on the design and communication of information. However, the view of the seeker as well as individual
differences in skills and abilities has been a neglected topic so far. A psychological perspective on the process of searching for health information would provide important starting points for promoting the general dissemination of relevant information and thus improving health behaviour and health status. Within the present dissertation, the process of seeking health information was thus divided into sequential stages to identify relevant personality traits and skills. Accordignly, three studies are presented that focus on one stage
of the process respectively and empirically test potential crucial traits and skills: Study I investigates possible determinants of an intention for a comprehensive search for health information. Building an intention is considered as the basic step of the search process.
Motivational dispositions and self-regulatory skills were related to each other in a structural equation model and empirically tested based on theoretical investigations. Model fit showed an overall good fit and specific direct and indirect effects from approach and avoidance
motivation on the intention to seek comprehensively could be found, which supports the theoretical assumptions. The results show that as early as the formation of intention, the psychological perspective reveals influential personality traits and skills. Study II deals with the subsequent step, the selection of information sources. The preference for basic characteristics of information sources (i.e., accessibility, expertise, and interaction) is related to health information literacy as a collective term for relevant skills and intelligence as a personality trait. Furthermore, the study considers the influence of possible over- or underestimation of these characteristics. The results show not only a different predictive
contribution of health literacy and intelligence, but also the relevance of subjective and objective measurement.
Finally, Study III deals with the selection and evaluation of the health information previously found. The phenomenon of selective exposure is analysed, as this can be considered problematic in the health context. For this purpose, an experimental design was implemented in which a varying health threat was suggested to the participants. Relevant information was presented and the selective choice of this information was assessed. Health literacy was tested
as a moderator in a function of the induced threat and perceived vulnerability, triggering defence motives on the degree of bias. Findings show the importance of the consideration of the defence motives, which could cause a bias in the form of selective exposure. Furthermore, health literacy even seems to amplify this effect.
Results of the three studies are synthesized, discussed and general conclusions are drawn and implications for further research are determined.
This dissertation details how Zeami (ca. 1363 - ca.1443) understood his adoption of the heavenly woman dance within the historical conditions of the Muromachi period. He adopted the dance based on performances by the Ōmi troupe player Inuō in order to expand his own troupe’s repertoire to include a divinely powerful, feminine character. In the first chapter, I show how Zeami, informed by his success as a sexualized child in the service of the political elite (chigo), understood the relationship between performer and audience in gendered terms. In his treatises, he describes how a player must create a complementary relationship between patron and performer (feminine/masculine or yin/yang) that escalates to an ecstasy of successful communication between the two poles, resembling sexual union. Next, I look at how Zeami perceived Inuō’s relationships with patrons, the daimyo Sasaki Dōyo in chapter two and shogun Ashikaga Yoshimitsu in chapter three. Inuō was influenced by Dōyo’s masculine penchant for powerful, awe-inspiring art, but Zeami also recognized that Inuō was able to complement Dōyo’s masculinity with feminine elegance (kakari and yūgen). In his relationship with Yoshimitsu, Inuō used the performance of subversion, both in his public persona and in the aesthetic of his performances, to maintain a rebellious reputation appropriate within the climate of conflict among the martial elite. His play “Aoi no ue” draws on the aristocratic literary tradition of the Genji monogatari, giving Yoshimitsu the role of Prince Genji and confronting him with the consequences of betrayal in the form of a demonic, because jilted, Lady Rokujō. This performance challenged Zeami’s early notion that the extreme masculinity of demons and elegant femininity as exemplified by the aristocracy must be kept separate in character creation. In the fourth chapter, I show how Zeami also combined dominance (masculinity) and submission (femininity) in the corporal capacity of a single player when he adopted the heavenly woman dance. The heavenly woman dance thus complemented not only the masculinity of his male patrons with femininity but also the political power of his patrons with another dominant power, which plays featuring the heavenly woman dance label divine rather than masculine.
The catechol-O-methyltransferase gene (COMT) plays a crucial role in the metabolism of catecholamines in the frontal cortex. A single nucleotide polymorphism (Val158Met SNP, rs4680) leads to either methionine (Met) or valine (Val) at codon 158, resulting in a three- to fourfold reduction in COMT activity. The aim of the present study was to assess the COMT Val158Met SNP as a risk factor for attention-deficit/hyperactivity disorder (ADHD), ADHD symptom severity and co-morbid conduct disorder (CD) in 166 children with ADHD. The main finding of the present study is that the Met allele of the COMT Val158Met SNP was associated with ADHD and increased ADHD symptom severity. No association with co-morbid CD was observed. In addition, ADHD symptom severity and early adverse familial environment were positive predictors of lifetime CD. These findings support previous results implicating COMT in ADHD symptom severity and early adverse familial environment as risk factors for co-morbid CD, emphasizing the need for early intervention to prevent aggressive and maladaptive behavior progressing into CD, reducing the overall severity of the disease burden in children with ADHD.
The equity premium (Mehra and Prescott, 1985) is still a puzzle in the sense that there are still no convincing explanations for the size of the equity premium. In this dissertation, we study this long-standing puzzle and several possible behavioral explanations. First, we apply the IRR methodology proposed by Fama and French (1999) to achieve large firm level data on the equity premia for N = 28,256 companies in 54 countries around the world. Second, by using preferences data from the INTRA study (Rieger et. al., 2014), we could test the relevant risk factors together with time cognition to explain the equity premium. We document the failure of the Myopic Loss Aversion hypothesis by Benartzi and Thaler (1995) but provides rigorous empirical evidence to support the behavioral theory of ambiguity aversion to account for the equity premium. The observations shed some light on the new approach of integrating risk and ambiguity (together with time preferences) into a more general model of uncertainty, in which both risk premium and ambiguity premium play roles in asset pricing models.
My study attempts to illustrate the generic development of the family novel in the second half of the twentieth century. At its beginning stands a preliminary classification of the various types of family fiction as they are referred to in secondary literature, which is then followed by a definition of the family novel proper. With its microscopic approach to novels featuring the American family and its (post-)postmodern variations, my study marks a first step into as yet uncharted territory. Assuming that the family novel has emerged as a result of the twentieth century's emphasis on the modern nuclear family, focuses on the family as a gestalt rather than on a single protagonist, and is concerned with issues of social and cultural significance, this study examines how the family, its forms and its conflicts are functionalized for the respective author's cultural critique. From post-war to post-millennium, family novelists have sketched the American family in various precarious conditions, and their texts are critical assessments of contemporary socioeconomic and cultural conditions. My close reading of John Cheever's The Wapshot Chronicle (1957), Don DeLillo's White Noise (1985) and Jonathan Franzen's The Corrections (2001) intends to reveal, shared values as well as significant differences on a formal as well as on a thematic level. As my examination of the respective novel shows, authors react to social and cultural change with new functionalizations of the family in fiction. Unlike the general assumption of literary crticism, family novels do not approach new cultural developments in a conventional or even traditionalist manner. A comparison of White Noise with The Wapshot Chronicle demonstrates that DeLillo's postmodern family novel transcends the rather nostalgic perspective of Cheever's 1950s work. Similarly, Jonathan Franzen's fin de millennium family novel The Corrections holds a post-postmodern position, which can be aptly described by Franzen's own term 'tragical realism'. The significant changes and developments of the family novel in the past five decades demonstrate the need for a continuous reassessment of the genre, and in this respect, my study is merely a beginning.
The Firepower of Work Craving: When Self-Control Is Burning under the Rubble of Self-Regulation
(2017)
Work craving theory addresses how work-addicted individuals direct great emotion-regulatory efforts to weave their addictive web of working. They crave work for two main emotional incentives: to overcompensate low self-worth and to escape (i.e., reduce) negative affect, which is strategically achieved through neurotic perfectionism and compulsive working. Work-addicted individuals" strong persistence and self-discipline with respect to work-related activities suggest strong skills in volitional action control. However, their inability to disconnect from work implies low volitional skills. How can work-addicted individuals have poor and strong volitional skills at the same time? To answer this paradox, we elaborated on the relevance of two different volitional modes in work craving: self-regulation (self-maintenance) and self-control (goal maintenance). Four hypotheses were derived from Wojdylo- work craving theory and Kuhl- self-regulation theory: (H1) Work craving is associated with a combination of low self-regulation and high self-control. (H2) Work craving is associated with symptoms of psychological distress. (H3) Low self-regulation is associated with psychological distress symptoms. (H4) Work craving mediates the relationships between self-regulation deficits and psychological distress symptoms at high levels of self-control. Additionally, we aimed at supporting the discriminant validity of work craving with respect to work engagement by showing their different volitional underpinnings. Results of the two studies confirmed our hypotheses: whereas work craving was predicted by high self-control and low self-regulation and associated with higher psychological distress, work engagement was predicted by high self-regulation and high self-control and associated with lower symptoms of psychological distress. Furthermore, work styles mediated the relationship between volitional skills and symptoms of psychological distress. Based on these new insights, several suggestions for prevention and therapeutic interventions for work-addicted individuals are proposed.
When humans encounter attitude objects (e.g., other people, objects, or constructs), they evaluate them. Often, these evaluations are based on attitudes. Whereas most research focuses on univalent (i.e., only positive or only negative) attitude formation, little research exists on ambivalent (i.e., simultaneously positive and negative) attitude formation. Following a general introduction into ambivalence, I present three original manuscripts investigating ambivalent attitude formation. The first manuscript addresses ambivalent attitude formation from previously univalent attitudes. The results indicate that responding to a univalent attitude object incongruently leads to ambivalence measured via mouse tracking but not ambivalence measured via self-report. The second manuscript addresses whether the same number of positive and negative statements presented block-wise in an impression formation task leads to ambivalence. The third manuscript also used an impression formation task and addresses the question of whether randomly presenting the same number of positive and negative statements leads to ambivalence. Additionally, the effect of block size of the same valent statements is investigated. The results of the last two manuscripts indicate that presenting all statements of one valence and then all statements of the opposite valence leads to ambivalence measured via self-report and mouse tracking. Finally, I discuss implications for attitude theory and research as well as future research directions.
The forward effect of testing refers to the finding that retrieval practice of previously studied information increases retention of subsequently studied other information. It has recently been hypothesized that the forward effect (partly) reflects the result of a reset-of-encoding (ROE) process. The proposal is that encoding efficacy decreases with an increase in study material, but testing of previously studied information resets the encoding process and makes the encoding of the subsequently studied information as effective as the encoding of the previously studied information. The goal of the present study was to verify the ROE hypothesis on an item level basis. An experiment is reported that examined the effects of testing in comparison to restudy on items’ serial position curves. Participants studied three lists of items in each condition. In the testing condition, participants were tested immediately on non-target lists 1 and 2, whereas in the restudy condition, they restudied lists 1 and 2. In both conditions, participants were tested immediately on target list 3. Influences of condition and items’ serial learning position on list 3 recall were analyzed. The results showed the forward effect of testing and furthermore that this effect varies with items’ serial list position. Early target list items at list primacy positions showed a larger enhancement effect than middle and late target list items at non-primacy positions. The results are consistent with the ROE hypothesis on an item level basis. The generalizability of the ROE hypothesis across different experimental tasks, like the list-method directed-forgetting task, is discussed.
The forward testing effect refers to the finding that retrieval practice of previously studied information enhances learning and retention of subsequently studied other information. While most of the previous research on the forward testing effect examined group differences, the present study took an individual differences approach to investigate this effect. Experiment 1 examined whether the forward effect has test-retest reliability between two experimental sessions. Experiment 2 investigated whether the effect is related to participants’ working memory capacity. In both experiments (and each session of Experiment 1), participants studied three lists of items in anticipation of a final cumulative recall test. In the testing condition, participants were tested immediately on lists 1 and 2, whereas in the restudy condition, they restudied lists 1 and 2. In both conditions, participants were tested immediately on list 3. On the group level, the results of both experiments demonstrated a forward testing effect, with interim testing of lists 1 and 2 enhancing immediate recall of list 3. On the individual level, the results of Experiment 1 showed that the forward effect on list 3 recall has moderate test-retest reliability between two experimental sessions. In addition, the results of Experiment 2 showed that the forward effect on list 3 recall does not depend on participants’ working memory capacity. These findings suggest that the forward testing effect is reliable at the individual level and affects learners at a wide range of working memory capacities alike. The theoretical and practical implications of the findings are discussed.
"Culture", in addition to its ethnic signification, can also express various groups' and communities' political and economic situation in society. As well as signifying the accommodation of ethnic diversity, the integration of dissimilar cultures in South Africa has to do with both the former oppressors and the formerly oppressed coming to terms with the oppression of the past, and with the equitable distribution of material means. Constitutional and other legal means have been designed to facilitate a process of integration dealing with the abovementioned issues. Some of these measures will be looked at. The speaker will argue that the integration of different cultures in South Africa cannot and will not be achieved if the law is invoked, in a strong arm fashion, trying to concoct a melting pot. The law can do no more than aiding the facilitation of a process of consolidation as precondition to nation building. Deep-seated, cultural differences among various sections of the population cannot and should not be denied or simply thought away.
Stress represents a significant problem for Western societies inducing costs as high as 3-4 % of the European gross national products, a burden that is continually increasing (WHO Briefing, EUR/04/5047810/B6). The classical stress response system is the hypothalamic-pituitary-adrenal (HPA) axis which acts to restore homeostasis after disturbances. Two major components within the HPA axis system are the glucocorticoid receptor (GR) and the mineralocorticoid receptor (MR). Cortisol, released from the adrenal glands at the end of the HPA axis, binds to MRs and with a 10 fold lower affinity to GRs. Both, impairment of the HPA axis and an imbalance in the MR/GR ratio enhances the risk for infection, inflammation and stress related psychiatric disorders. Major depressive disorder (MDD) is characterised by a variety of symptoms, however, one of the most consistent findings is the hyperactivity of the HPA axis. This may be the result of lower numbers or reduced activity of GRs and MRs. The GR gene consists of multiple alternative first exons resulting in different GR mRNA transcripts whereas for the MR only two first exons are known to date. Both, the human GR promoter 1F and the homologue rat Gr promoter 1.7 seem to be susceptible to methylation during stressful early life events resulting in lower 1F/1.7 transcript levels. It was proposed that this is due to methylation of a NGFI-A binding site in both, the rat promoter 1.7 and the human promoter 1F. The research presented in this thesis was undertaken to determine the differential expression and methylation patterns of GR and MR variants in multiple areas of the limbic brain system in the healthy and depressed human brain. Furthermore, the transcriptional control of the GR transcript 1F was investigated as expression changes of this transcript were associated with MDD, childhood abuse and early life stress. The role of NGFI-A and several other transcription factors on 1F regulation was studied in vitro and the effect of Ngfi-a overexpression on the rat Gr promoter 1.7 in vivo. The susceptibility to epigenetic programming of several GR promoters was investigated in MDD. In addition, changes in methylation levels have been determined in response to a single acute stressor in rodents. Our results showed that GR and MR first exon transcripts are differentially expressed in the human brain, but this is not due to epigenetic programming. We showed that NGFI-A has no effect on endogenous 1F/1.7 expression in vitro and in vivo. We provide evidence that the transcription factor E2F1 is a major element in the transcriptional complex necessary to drive the expression of GR 1F transcripts. In rats, highly individual methylation patterns in the paraventricular nucleus of the hypothalamus (PVN) suggest that this is not related to the stressor but can rather be interpreted as pre-existing differences. In contrast, the hippocampus showed a much more uniform epigenetic status, but still is susceptible to epigenetic modification even after a single acute stress suggesting a differential "state‟ versus "trait‟ regulation of the GR gene in different brain regions. The results of this thesis have given further insight in the complex transcriptional regulation of GR and MR first exons in health and disease. Epigenetic programming of GR promoters seems to be involved in early life stress and acute stress in adult rats; however, the susceptibility to methylation in response to stress seems to vary between brain regions.
This guide is meant to provide some initial bibliographical assistance to those who want to study the historical evolution of ecological thinking in Canada on the basis of poetry. A major theoretical assumption underlying this project is that literature gives privileged access to a nation's cultural memory. Even a cursory survey of Canadian literary history supplies ample evidence for the marked presence of ecological attitudes in Canada's mental history. The origin of these attitudes can be traced back to at least the 18th century. By way of generalising, one could argue that literature reflects, and provides subtle insights into, how both native Canadians and immigrant settlers have responded to their 'eco-sphere'. For many Canadian texts bear witness to a thematic preoccupation with the Canadian oikos-area (oikos signifying 'house' in a narrower sense but also 'habitat' in a wider), to which its inhabitants have established a meaningful relationship. No doubt, even a preliminary attempt to explore ecological attitudes in Canadian literature more systematically would be a multi-facetted and difficult task. One of the major practical problems that poses itself immediately is: Which texts could, and ought to be examined? For there are innumerous references to environmental attitudes and ideas in all literary genres -- also in a great many fictional texts, both traditional and contemporary. For the purpose of research and study it would be extremely helpful indeed, if there were comprehensive bibliographical aids that would enable us to approach, and familiarize ourselves with, all these texts more conveniently. But the challenge of collecting pertinent data of this general kind would have been far beyond my scope and resources. This is why the present guide limits its focus to poetry. The working hypotheses motivating this tentative compilation are: i. Poetry is a more ubiquitous literary genre than fiction and drama. According to available evidence, more writers seem to have tried out their skills on poetry than on fiction and drama. Therefore poetry is likely to mirror a greater variety of voices and sentiments. ii. Poems are still a relatively untapped source in the current discussion about the environment. However, a great many poetic texts lend themselves to supplying relevant arguments that could be used in various fields of action such as environmental ethics, evironmental education and, last but not least, conservation. iii. Apart from smaller pieces of the "nature writing" variety, poems dealing with nature and environmental issues are comparatively short, aiming as they do at a single focus and effect. This is why they can be opened up for critical inspection more easily than selected passages from, say, a novel, which would have to be related to the context of the whole work. iv. This guide attempts to direct the user's attention to poems that are accessible in anthologies. A strong argument for selecting poems from anthologies rather than from individual writers' collections is that the anthology editors are likely to have selected precisely those poems of whose appeal to their respective readerships they must have been thoroughly convinced. Thus the mere fact that a poem has been anthologized suggests that it can be considered an important element in the process of Canadian culture building. Therefore, the very poems that have been frequently anthologized could perhaps serve as special barometers of the Canadian ecological sensibility at a given historical moment.
The thesis studies the question how universal behavior is inherited by the Hadamard product. The type of universality that is considered here is universality by overconvergence; a definition will be given in chapter five. The situation can be described as follows: Let f be a universal function, and let g be a given function. Is the Hadamard product of f and g universal again? This question will be studied in chapter six. Starting with the Hadamard product for power series, a definition for a more general context must be provided. For plane open sets both containing the origin this has already been done. But in order to answer the above question, it becomes necessary to have a Hadamard product for functions that are not holomorphic at the origin. The elaboration of such a Hadamard product and its properties are the second central part of this thesis; chapter three will be concerned with them. The idea of the definition of such a Hadamard product will follow the case already known: The Hadamard product will be defined by a parameter integral. Crucial for this definition is the choice of appropriate integration curves; these will be introduced in chapter two. By means of the Hadamard product- properties it is possible to prove the Hadamard multiplication theorem and the Borel-Okada theorem. A generalization of these theorems will be presented in chapter four.
The harmonic Faber operator
(2018)
P. K. Suetin points out in the beginning of his monograph "Faber Polynomials and Faber Series" that Faber polynomials play an important role in modern approximation theory of a complex variable as they are used in representing analytic functions in simply connected domains, and many theorems on approximation of analytic functions are proved with their help [50]. In 1903, the Faber polynomials were firstly discovered by G. Faber. It was Faber's aim to find a generalisation of Taylor series of holomorphic functions in the open unit disc D in the following way. As any holomorphic function in D has a Taylor series representation f(z)=\sum_{\nu=0}^{\infty}a_{\nu}z^{\nu} (z\in\D) converging locally uniformly inside D, for a simply connected domain G, Faber wanted to determine a system of polynomials (Q_n) such that each function f being holomorphic in G can be expanded into a series
f=\sum_{\nu=0}^{\infty}b_{\nu}Q_{\nu} converging locally uniformly inside G. Having this goal in mind, Faber considered simply connected domains bounded by an analytic Jordan curve. He constructed a system of polynomials (F_n) with this property. These polynomials F_n were named after him as Faber polynomials. In the preface of [50], a detailed summary of results concerning Faber polynomials and results obtained by the aid of them is given. An important application of Faber polynomials is e.g. the transfer of known assertions concerning polynomial approximation of functions belonging to the disc algebra to results of the approximation of functions being continuous on a compact continuum K which contains at least two points and has a connected complement and being holomorphic in the interior of K. In this field, the Faber operator denoted by T turns out to be a powerful tool (for an introduction, see e.g. D. Gaier's monograph). It
assigns a polynomial of degree at most n given in the monomial basis \sum_{\nu=0}^{n}a_{\nu}z^{\nu} with a polynomial of degree at most n given in the basis of Faber polynomials \sum_{\nu=0}^{n}a_{\nu}F_{\nu}. If the Faber operator is continuous with respect to the uniform norms, it has a unique continuous extension to an operator mapping the disc algebra onto the space of functions being continuous on the whole compact continuum and holomorphic in its interior. For all f being element of the disc algebra and all polynomials P, via the obvious estimate for the uniform norms ||T(f)-T(P)||<= ||T|| ||f-P||, it can be seen that the original task of approximating F=T(f) by polynomials is reduced to the polynomial approximation of the function f. Therefore, the question arises under which conditions the Faber operator is continuous and surjective. A fundamental result in this regard was established by J. M. Anderson and J. Clunie who showed that if the compact continuum is bounded by a rectifiable Jordan curve with bounded boundary rotation and free from cusps, then the Faber operator with respect to the uniform norms is a topological isomorphism. Now, let f be a harmonic function in D. Similar as above, we find that f has a uniquely determined representation f=\sum_{\nu=-\infty}^{\infty}a_{\nu}p_{\nu}
converging locally uniformly inside D where p_{n}(z)=z^{n} for n\in\N_{0} and p_{-n}(z)=\overline{z}^{n} for n\in\N}. One may ask whether there is an analogue for harmonic functions on simply connected domains G. Indeed, for a domain G bounded by an analytic Jordan curve, the conjecture that each function f being harmonic in G has a uniquely determined representation f=\sum_{\nu= \infty}^{\infty}b_{\nu}F_{\nu} where F_{-n}(z)=\overline{F_{n}(z\)} for n\inN, converging locally uniformly inside G, holds true. Let now K be a compact continuum containing at least two points and having a connected complement. A main component of this thesis will be the examination of the harmonic Faber operator mapping a harmonic polynomial given in the basis of the harmonic monomials \sum_{\nu=-n}^{n}a_{\nu}p_{\nu} to a harmonic polynomial given as \sum_{\nu=-n}^{n}a_{\nu}F_{\nu}.
If this operator, which is based on an idea of J. Müller, is continuous with respect to the uniform norms, it has a unique continuous extension to an operator mapping the functions being continuous on \partial\D onto the continuous functions on K being
harmonic in the interior of K. Harmonic Faber polynomials and the harmonic Faber operator will be the objects accompanying us throughout
our whole discussion. After having given an overview about notations and certain tools we will use in our consideration in the first chapter, we begin our studies with an introduction to the Faber operator and the harmonic Faber operator. We start modestly and consider domains bounded by an analytic Jordan curve. In Section 2, as a first result, we will show that, for such a domain G, the harmonic Faber operator has a unique continuous extension to an operator mapping the space of the harmonic functions in D onto the space
of the harmonic functions in G, and moreover, the harmonic Faber
operator is an isomorphism with respect to the topologies of locally
uniform convergence. In the further sections of this chapter, we illumine the behaviour of the (harmonic) Faber operator on certain function spaces. In the third chapter, we leave the situation of compact continua bounded by an analytic Jordan curve. Instead we consider closures of domains bounded by Jordan curves having a Dini continuous curvature. With the aid of the concept of compact operators and the Fredholm alternative, we are able to show that the harmonic Faber operator is a topological isomorphism. Since, in particular, the main result of the third chapter holds true for closures K of domains bounded by analytic Jordan curves, we can make use of it to obtain new results concerning the approximation of functions being continuous on K and harmonic in the interior of K by harmonic polynomials. To do so, we develop techniques applied by L. Frerick and J. Müller in [11] and adjust them to our setting. So, we can transfer results about the classic Faber operator to the harmonic Faber operator. In the last chapter, we will use the theory of harmonic Faber polynomials
to solve certain Dirichlet problems in the complex plane. We pursue
two different approaches: First, with a similar philosophy as in [50],
we develop a procedure to compute the coefficients of a series \sum_{\nu=-\infty}^{\infty}c_{\nu}F_{\nu} converging uniformly to the solution of a given Dirichlet problem. Later, we will point out how semi-infinite programming with harmonic Faber polynomials as ansatz functions can be used to get an approximate solution of a given Dirichlet problem. We cover both approaches first from a theoretical point of view before we have a focus on the numerical implementation of concrete examples. As application of the numerical computations, we considerably obtain visualisations of the concerned Dirichlet problems rounding out our discussion about the harmonic Faber polynomials and the harmonic Faber operator.
The skin is continuously challenged by environmental antigens that may penetrate and elicit a skin sensitization, which can develop into allergic contact dermatitis. Medical treatment for allergic contact dermatitis is limited - in fact only acute symptoms can be cured and for secondary prevention of the disease a lifelong avoidance of the allergen(s) is necessary. Therefore, the screening of the sensitization potential of substance used in commercially available products is indispensable to prevent such diseases. Hence, risk assessment is deduced from data obtained by murine local lymph node assay predominantly, but there exists a need to develop methods capable of providing the same information that do not require the use of animals in view of legislative initiatives such as REACH (registration, evaluation, authorization of chemicals) as well as the 7th Amendment to the Cosmetics Directive (2003/15/EC). Therefore, a number of promising in silico and in vitro approaches are being developed to address this need. In vitro test systems using the response of dendritic cells, which are the key player in the elicitation process of contact dermatitis, are established, but, although these novel methods for hazard identification might find application in the context of screening, it is not clear whether these approaches are useful for the purposes of risk assessment and risk management to predict allergic potency. Therefore, it was investigated whether on the one hand in vitro generated dendritic cells from primary blood monocytes (MoDC) and on the other hand a continuous monocytic cell line, the THP-1 cells, suggested as dendritic cell surrogate, react to a presumably weak allergen. Ascaridol, predicted as one of the possible causes for tea tree oil contact dermatitis, was studied and its effects in these two in vitro skin sensitization models were explored. Thus, the surface expression of CD86, HLADR, CD54, and CD40, which are known as activation markers in both in vitro models, were measured via flow cytometry. For MoDC, an augmented CD86 and HLADR surface expression in comparison to untreated cells were determined after 24 h exposure with ascaridol. An increased CD54 and CD40 surface expression were found only in some donors. After long term incubation of 96 h, ascaridol-treated MoDC still up-regulated CD86 and additionally an augmented CD40 expression was measured in all studied donors. An enhanced CD54 expression was determined for 50 percentage of all investigated donors. Furthermore, CD80, CD83 and CD209 protein expression were up-regulated in MoDC after 96 h of ascaridol incubation. In addition, it was determined that after 24 h ascaridol-treated MoDC showed an increased capacity to uptake antigens, whereas after 96 h this capacity got lost and antigen-capturing devices were reduced in comparison to non-treated MoDC. Moreover, the cytokine release of ascaridol-treated MoDC were measured after 24 h. Tumor necrosis factor (TNF)alpha, interleukin (IL)-1beta and IL 6 secretion were determined in some donors. Furthermore, IL-8 release was clearly increased after 24 h ascaridol treatment. By the same token, THP-1 cells were analyzed after ascaridol treatment for several activation markers. We found a similar response pattern as measured in MoDC. Ascaridol induced CD86 expression as well as CD54 after 24 h incubation. Additionally, the impact of ascaridol on phosphorylation of p38 mitogen-activated protein kinase, which had been shown to be involved in increased expression of activation markers like CD86 by others, were studied via Western blot analysis. A phosphorylation of p38 was determined after 15 min of ascaridol stimulation. Moreover, an augmented CD40 and HLADR surface expression were measured in a dose-response manner after 24 h ascaridol treatment. Also similar to MoDC an enhanced IL-8 secretion after ascaridol stimulation was observed in THP-1 cells. Hence, for the first time it was shown that ascaridol has immuno-modulating effects. The obtained data from both in vitro systems, MoDC and THP-1 cells, identified ascaridol as a sensitizer. Although for both systems there remain significant challenges to overcome for potency assessment, ascaridol is presumed to be a weak sensitizer probably. Interestingly, ascaridol treatment of THP-1 cells resulted also in an increased augmentation of CD184 and CCR2, two chemokine receptors expressed on monocyte. Therefore, these data encouraged the exploration of chemokine receptors as tools in skin sensitization prediction. Consequently, the combination of chemical assays with in vitro techniques may provide a useful surrogate to animal testing for skin sensitization. Due to the continuously changing environmental conditions, it is necessary to regularly monitor and update the spectrum of sensitizers that elicit contact dermatitis. Therefore, both debated in vitro test systems will become indispensable tools.
Die vorliegende Arbeit umfasst ein Modell der Zusammenhänge zwischen Führungsverhalten und psychologischen Kontrakten als Einflussfaktoren mitarbeiterbezogener Einstellungen. Auf Seiten der Konsequenzen liegt der Fokus insbesondere auf der Entgeltzufriedenheit der Mitarbeiter. Jede der drei in der Dissertation dargestellten Studien trägt zu dem Verständnis bei, wie sich das Führungsverhalten und psychologische Kontrakte auf die Entgeltzufriedenheit auswirken. Die erste Studie stellt den Zusammenhang zwischen transformationaler Führung und Arbeits- und Entgeltzufriedenheit sowie dem Commitment in den Vordergrund. Zusätzlich wird untersucht, inwiefern der Effekt des Führungsverhaltens durch verschiedene Formen des psychologischen Kontrakts vermittelt wird. Auf Basis dieser Ergebnisse wird in einer zweiten Studie geprüft, inwiefern Entgeltzufriedenheit als multidimensionales Konstrukt betrachtet werden kann. Ferner wird transformationales mit transaktionalem Führungsverhalten kontrastiert, um deren differentielle Effekte zu analysieren. In einer dritten Studie werden die kausalen Beziehungen fokussiert, indem eine Stichprobe von 169 Mitarbeitern aus acht caritativen Unternehmen, in denen leistungsabhängige Vergütungssysteme implementiert wurden, analysiert wird. Zusammenfassend zeigen die Ergebnisse, dass die perzeptuellen Variablen Führung und psychologische Kontrakte als entscheidende Einflussfaktoren der Entgeltzufriedenheit dienen. Eine Diskussion der theoretischen und praktischen Implikationen schließt die Arbeit ab.
As an interface between an individual and its environment, the skin is a major site of direct exposure to exogenous substances. Once absorbed, these substances may interact with different biomolecules within the skin. The aryl hydrocarbon receptor (AhR) signaling pathway is one mechanism whereby the skin responds to exposures, predominantly through the induction or upregulation of metabolizing enzymes. One known physiological role of the AhR in many tissues is its involvement in the control of cell cycle progression. In skin, almost nothing is known about this physiological function. Moreover, the question whether frequently used naturally occurring phenolic derivatives like eugenol and isoeugenol impact on the AhR within the skin has rarely been studied so far. Eugenol and isoeugenol are due to their odour referred to as fragrances. The ubiquitous distribution of eugenol and isoeugenol results in an almost unavoidable contact with these substances in our daily lives. Despite this fact, their molecular mechanisms of action in skin are poorly understood. There is evidence supporting the hypothesis that these substances may impact on the AhR. On the one hand, eugenol is shown to induce cytochrome P450 1A1 (CYP1A1), a well-known target gene of the AhR. On the other hand, their known anti-proliferative properties might also be mediated by the AhR, based on its physiological function. In order to proof this hypothesis, it was investigated whether eugenol and isoeugenol impact on the AhR signaling pathway in skin cells. Results revealed that eugenol as well as isoeugenol impact on the AhR signaling pathway in skin cells. Both substances caused the translocation of the AhR into the nucleus, induced the expression of the well-known AhR target genes CYP1A1 and AhR repressor (AhRR) and exhibited impact on cell cycle progression. Both substances caused an AhR-dependent cell cycle arrest in skin cells, modulated protein levels of several cell cycle regulatory proteins, inhibited DNA synthesis and thereby reduced cell numbers. The comparison of wildtype cells to AhR knockdown cells revealed an influence of the AhR on cell cycle progression in skin cells in the absence of exogenous ligands. AhR knockdown cells exhibited a slower progression through the cell cycle caused by an accumulation of cells in the G0/G1 phase of the cell cycle and a decreased DNA synthesis rate. Modulation of cell cycle regulatory proteins involved in the transition from the G0/G1 to the S phase of the cell cycle was altered in AhR knockdown cells as well. To conclude, eugenol as well as isoeugenol were able to impact on the AhR signaling pathway in skin cells. Their molecular mechanisms of action are similar to those of classical AhR ligands, although their structural characteristics strongly differ from that of these ligands. In the absence of exogenous ligands the AhR promotes cell cycle progression in many tissues and this knowledge could be expanded on skin-derived cells within the scope of this thesis.
The Belt and Road Initiative (BRI) has had a significant impact on China in political, economic, and cultural terms. This study focuses on the cultural domain, especially on scholarship students from the countries that signed bilateral cooperation agreements with China under the BRI. Using an integrated approach combining the difference-in-differences method and the gravity model, we explore the correlation between the BRI and the increasing number of international scholarship students funded by the Chinese government, as well as the determinants of students' decision to study in China. The panel data from 2010 to 2018 show that the launch of BRI has had a positive impact on the number of scholarship students from BRI countries. The number of scholarship recipients from non-BRI countries also increased, but at a much slower rate than those from BRI countries. The sole exception is the United States, which has trended downward for both state-funded and self-funded students.
The present dissertation was developed to emphasize the importance of self-regulatory abilities and to derive novel opportunities to empower self-regulation. From the perspective of PSI (Personality Systems Interactions) theory (Kuhl, 2001), interindividual differences in self-regulation (action vs. state orientation) and their underlying mechanisms are examined in detail. Based on these insights, target-oriented interventions are derived, developed, and scientifically evaluated. The present work comprises a total of four studies which, on the one hand, highlight the advantages of a good self-regulation (e.g., enacting difficult intentions under demands; relation with prosocial power motive enactment and well-being). On the other hand, mental contrasting (Oettingen et al., 2001), an established self-regulation method, is examined from a PSI perspective and evaluated as a method to support individuals that struggle with self-regulatory deficits. Further, derived from PSI theory`s assumptions, I developed and evaluated a novel method (affective shifting) that aims to support individuals in overcoming self-regulatory deficits. Thereby affective shifting supports the decisive changes in positive affect for successful intention enactment (Baumann & Scheffer, 2010). The results of the present dissertation show that self-regulated changes between high and low positive affect are crucial for efficient intention enactment and that methods such as mental contrasting and affective shifting can empower self-regulation to support individuals to successfully close the gap between intention and action.